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To determine if an inhibition of the endocannabinoid-degrading enzyme fatty acid amide hydrolase (FAAH) can counteract the changes in urodynamic parameters and bladder afferent activities induced by intravesical prostaglandin E2 (PGE2 )-instillation, we studied effects of URB937, a peripherally-restricted FAAH inhibitor, on single-unit afferent activity (SAA) during PGE2 -induced bladder overactiv
Popular Abstract in Swedish Bibelhebreiskans verbsystem (som radikalt skiljer sig från den moderna hebreiskans) har fascinerat exegeter, lingvister, teologer och översättare under århundraden, ja, årtusenden. Liksom många språk av utomeuropeiskt ursprung har den klassiska hebreiskan inte riktigt passat i den kostym som traditionell grammatik försett den med. Den traditionella grammatiken är modelThe verbal system of Biblical Hebrew has intrigued the minds of exegetes, linguists, theologians, and translators for centuries. With regard to the verbal system, Biblical Hebrew is radically different from Modern Hebrew. Furthermore, it doesn't fit the traditional structure of grammar modelled on Latin. It is argued that the interpretive categories of aspect, temporal location, and modality shou
Repetitive work and work in constrained postures are risk factors for developing musculoskeletal disorders. Low-cost, user-friendly technical methods to quantify these risks are needed. The aims were to validate inclination angles and velocities of one model of the new generation of accelerometers with integrated data loggers against a previously validated one, and to compare meaurements when usin
This thesis investigates the European Union’s Carbon Border Adjustment Mechanism (CBAM) as a novel intersection between climate regulation and international trade law. It explores the extent to which CBAM serves as a legitimate environmental measure under EU and World Trade Organization (WTO) legal frameworks or whether it risks functioning as a de facto instrument of protectionism. This is partic
Kelp forests are among the most productive ecosystems on Earth, releasing detritus year-round through direct blade erosion, storm-induced detachment, wave breakage, seasonal shedding, as well as indirect urchin grazing. Fragmental kelp detritus is transported from the euphotic zone to deeper parts of the ocean such as fjords, where decomposition rates are very low and detritus may contribute to lo
This thesis examines whether the partially owned parent entity (POPE) rule in the Directive (EU) 2022/2523 (P2D) creates a restriction on the free movement of capital under Article 63 TFEU, and if so, whether that restriction be justified and regarded as proportionate under EU law. The POPE rule forms part of the EU implementation of Pillar Two, which aims to ensure a global minimum level of taxa
This thesis is motivated by the aim of ascertaining whether the ECtHR is limiting the ECHR’s potential, if any, to contribute to the curbing of child welfare disproportionality rates in CoE MSs. It provides a critical analysis of ECtHR jurisprudence on child protection interventions involving minority children – namely, children belonging to ethnic, religious, or linguistic minority groups or whos
This qualitative study examines how professionals describe support provided by selected support services for men who have been subjected to sexual violence and analyses how these descriptions can be understood in relation to norms of masculinity. The study is based on seven semi-structured interviews with professionals from different support services, including health care, social services, and lo
Proteins are useful chiral selectors. In order to understand the recognition mechanism and chiral discrimination, the binding of the (R)- and (S)-enantiomers of a series of designed amino alcohol inhibitors based on propranolol to cellobiohydrolase Cel7A (Trichoderma reesei) has been studied more closely. X-ray crystal structures were determined of the protein complex with the (R)- and (S)-enantio
Introduction The Problematic Experience of Therapy Scale (PETS) identifies barriers to home-based exercise programs but has not been validated in hand therapy populations. This study aimed to translate the extended PETS into Swedish and evaluate its content and construct validity in patients undergoing early sensory relearning following peripheral nerve injury.Methods The PETS was translated into
A search for pair production of vector-like leptons coupling to first- and second-generation Standard Model leptons is presented. The search is based on a dataset of proton-proton collisions at s = 13 TeV recorded with the ATLAS detector during Run 2 of the Large Hadron Collider, corresponding to an integrated luminosity of 140 fb−1. Events are categorised depending on the flavour and multiplicity
A search is performed for light, spin-0 bosons decaying into two photons in the 66 to 110 GeV mass range, using 140 fb−1 of proton-proton collisions at s = 13 TeV produced by the Large Hadron Collider and collected by the ATLAS detector. Multivariate analysis techniques are used to define event categories that improve the sensitivity to new resonances beyond the Standard Model. A model-independent
