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Identification of Non-HLA Genes Associated with Celiac Disease and Country-Specific Differences in a Large, International Pediatric Cohort RESEARCH ARTICLE Identification of Non-HLA Genes Associated with Celiac Disease and Country-Specific Differences in a Large, International Pediatric Cohort Ashok Sharma1, Xiang Liu2, David Hadley2,3, William Hagopian4, Edwin Liu5, Wei- Min Chen6, Suna Onengut-G

https://www.teddy.lu.se/sites/teddy.lu.se/files/2021-11/55%2006032016_679_55_Sharma_PlosOne_2016.pdf - 2026-07-17

I februari 2018 meddelades en friande misshandelsdom från Solna tingsrätt som väckte stor uppståndelse. Avgörandet var en så kallad nämndemannadom, alltså en dom där nämndemännen (lekmännen) i rätten bestämt utgången i målet i strid med den lagfarne domarens mening. Utöver omfattande kritik i media väckte domen även på nytt upp diskussionen om nämndemännens vara eller inte vara. Denna uppsats utreIn February 2018, a Swedish district court passed a sentence in an assault case that was heavily criticized by the public. The sentence was decided by lay judges contrary to the opinion of the professional judge in the case. The ruling reignited a debate in Sweden about its legal system with lay judges, who serve as part of the bench and are used instead of a jury in criminal cases in district cou

Syftet med denna uppsats har varit att utvärdera effekten av korttidsfamiljebehandling med fokus på förändringar i familjens känslomässiga klimat och förändringar av symtom hos det barn som är identifierad patient. Arbetet utgick från frågorna: Hur förändras upplevelsen hos de olika familjemedlemmarna avseende familjens känslomässiga klimat? Upplever barnet en symtomminskning? Upplever föräldrarnaThe purpose of this paper was to evaluate the effect of a short-term family treatment regarding changes in the family's emotional climate and changes in the symptoms of the child. The work was based on the questions: How does family members experience the family's emotional climate? Does the child experience a decrease in symptoms? Do the parents experience a decrease in the symptoms of th

Bakgrund: Studier har visat att partners som blev involverade i den perinatala vården hade mer positiv upplevelse av förlossningen. Barnmorskan har en betydelsefull uppgift med att inkludera och stödja partners i samband med förlossning. Covid- 19 pandemi har lett till att partners närvaro begränsats av besöksförbud. Syfte: Att belysa partners upplevelse i samband med graviditet och barnafödande

In this paper we report that single-walled carbon nanotubes (SWNTs) can protect surface adsorbed Rhodamine B (RhB) molecules from permanent photo-oxidation via a reversible reaction. Upon strong light irradiation at 514 nm, the SWNT-adsorbed RhB molecules were switched to a non-fluorescent form, which looked like ordinary bleaching behavior. However, after staying without light for several hours t

OBJECTIVE: To identify how the gp130-signaling cytokine oncostatin M (OSM), acting alone or in concert with IL-1beta or TNFalpha, affects synovial fibroblast expression of genes relevant to inflammation and bone erosion in inflammatory arthritis. METHODS: Synovial fibroblasts (SFs) were isolated from non-arthritic wild type (WT) or OSM receptor deficient (OSMR(-/-)) mice and stimulated with OSM, I

Background: Research in recent decades increasingly indicates the importance of conditions in early life for health in adulthood. Only few studies have investigated socioeconomic conditions in both childhood and adulthood in relation to health testing the risk accumulation, critical period, and social mobility hypotheses within the same setting. This study investigates the associations between eco

Recently there has been growing interest in the role of coherence in electronic dynamics. Coherent multidimensional spectroscopy has been used to reveal coherent phenomena in numerous material systems. Here we utilize a recent implementation of coherent multidimensional spectroscopy-two-dimensional photocurrent spectroscopy-in which we detect the photocurrent from a PbS quantum dot photocell resul

A fundamental precept of geochemistry is that arsenate coordinates at mineral surfaces in a predominately bridging-bidentate fashion. We show that this is incorrect for the model system, arsenate adsorbed at the surface of goethite (alpha-FeOOH), using a combination of XRD, EXAFS, and IR spectroscopic results. We report the crystal structure of pentaamminecobalt(III) arsenate, which consists of mo

Purposes To assess predictors of presenteeism (reduced productivity at work) and activity impairment outside work in patients with spondyloarthritis (SpA). Methods Multivariate logistic regression analysis was used to study predictors of presenteeism and activity impairment in 1,253 patients with SpA based on a 2.5 year follow-up questionnaire. The Work Productivity and Activity Impairment (WPAI)

The insulin-like growth factor (IGF) pathway has been implicated as risk modifier in premenopausal breast cancer. In this study, associations between single nucleotide polymorphisms (SNPs) and diplotypes in the IGFBP1 and IGFBP3 genes and circulating IGFBP-3 levels, BRCA family status and breast cancer among women from high-risk breast cancer families were investigated. Nine IGFBP1 and IGFBP3 SNPs

The concept of a digital cavity is presented. The functionality of a tunable radio-frequency/microwave cavity with unrestricted Q-factor is implemented. The theoretical aspects of the cavity and its potential applications in high resolution spectroscopy and synchronization of clocks together with examples in signal processing and data acquisition are discussed.

A third generation glucose biosensor working under physiological conditions with a linear range of 0.1-30 mM, a detection limit of 0.05 mM, and a sensitivity of 222 nA microM(-1) cm(-2) has been developed by co-adsorption of cellobiose dehydrogenase (CDH) from the ascomycete Corynascus thermophilus (CtCDH) and oxidatively shortened single-walled carbon nanotubes (SWCNTs).

Exposure to diesel exhaust causes inflammatory responses. Previous controlled exposure studies at a concentration of 300 μg/m(3) of diesel exhaust particles mainly lasted for 1 h. We prolonged the exposure period and investigated how quickly diesel exhaust can induce respiratory and systemic effects.

Background: Low blood levels of vitamin D (25-hydroxy D3, 25OHD3) in women have been associated with an increased risk of several diseases. A large part of the population may have suboptimal 25OHD3 levels but high-risk groups are not well known. The aim of the present study was to identify determinants for serum levels of 25OHD3 in women, i.e. factors such as lifestyle, menopausal status, diet and

One classical feature of cancer cells is their metabolic acquisition of a highly glycolytic phenotype. Carbon monoxide (CO), one of the products of the cytoprotective molecule heme oxygenase-1 (HO-1) in cancer cells, has been implicated in carcinogenesis and therapeutic resistance. However, the functional contributions of CO and HO-1 to these processes are poorly defined. In human prostate cancers

This study analyzed predictors of psychiatric hospitalization in ex-prisoners with substance use problems (N = 4,081) assessed with the Addiction Severity Index and followed post-release for hospitalizations with psychiatric diagnoses (including suicide attempts). Thirty-four percent were hospitalized, and in Cox regression, several substance-related variables predicted hospitalization, including

Single chains of conjugated polymers e.g. MEH-PPV (poly(2-methoxy-5-(2'-ethylhexyloxy)-1,4-phenylenevinylene) have become interesting objects for single molecule spectroscopy (SMS) studies. However, most of the experiments so far were performed without full awareness of the isolation status of the polymer chains in host matrices. We used steady-state and time-resolved fluorescence methods and 2D p