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AbstractIntroductionWork environments are rapidly changing in Europe, with climate change, the transition to the circular economy, and expansion of work in green jobs among key factors. Research and interventions are urgently needed to promote worker health and well-being. The European Union (EU) INTERCAMBIO project is the first large-scale initiative to systematically assess mental and physical h

Purpose of review – Aging is associated with impaired B lymphopoiesis and T lymphopoiesis, contributing to immunosenescence and poor immune recovery. Although this decline can be attributed to intrinsic hematopoietic stem cell aging, growing evidence indicates that lymphoid failure reflects constraints operating across multiple levels of the hematopoietic system. This review frames age-associated

Compacted graphite iron (CGI) is an intermediate material between conventional grey cast iron and the stronger, more wear resistant ductile iron, making it a suitable material choice for different automotive applications. The improved material properties of CGI as to conventional grey cast iron makes it more difficult to machine, and finding a suitable tool material with low wear rates is a challe

Objective. Prior incidence estimates of psoriatic arthritis (PsA) vary considerably. We aimed to assess the annual incidence of clinically diagnosed PsA among adults in Sweden in 2014-2016, overall and stratified by age/sex/education/geography, and to investigate potential time trends in incidence in 2006-2018. Use of disease-modifying antirheumatic drugs (DMARDs) during the 2 years after diagnosi

We study the association between childhood neighborhood socioeconomic status (SES) (ages 1-15) and hospitalization with preventable-type disease in adulthood, using geocoded longitudinal microdata for a Swedish city (1939-1967) linked to national registers (1973-2015). Observing the full residential histories at the address level for the entire population, we construct dynamic and cumulative indiv

BackgroundCritical COVID-19 is associated with high mortality, and acute kidney injury (AKI) is common. Endostatin has emerged as a promising prognostic biomarker for predicting AKI and mortality in intensive care. This study aimed to investigate plasma endostatin at intensive care unit (ICU) admission as a biomarker for AKI, renal replacement therapy (RRT), and 90-day mortality in COVID-19.Method

Background: Certain species from the normal respiratory tract microbiota have recently been proposed to positively influence human health. Corynebacterium propinquum and C. pseudodiphtheriticum (Corynebacteria) are two Gram-positive species that frequently colonize the upper respiratory tract and strongly associate with a reduced incidence of respiratory tract infections. The specific role of Cory

Bimetallic nanoparticles exhibit unique physicochemical characteristics that often translateinto functional properties surpassing those of their monometallic counterparts. The abilityto precisely tailor these characteristics enables fine-tuning of their properties for targetedapplications. This doctoral thesis investigates the engineering of bimetallic nanoparticlesvia spark ablation, a continuous

The functionalization of cubosomes for their use in drug delivery, bioimaging, and biosensing can be achieved by incorporating molecules that are sensitive to physiological conditions, such as phospholipids. Considering this, it is relevant to investigate the interaction between phospholipid-containing cubosomes and phospholipase A2 (PLA2), a ubiquitous enzyme associated with inflammatory diseases

Overtourism has emerged as a pressing challenge for many destinations, but its manifestations and impacts vary in different geographical and socio-political contexts. This chapter examines overtourism as a situated phenomenon from a Nordic perspective, focusing on how place-based conflicts arise in urban and peri-urban areas. Drawing on instances from different locations, we analyse the ways in wh

Introduction: Exposure to environmental chemicals during fetal development may increase the risk of testicular germ cell cancer (TGCC), but few studies have tested the hypothesis. We focused on organochlorine pesticides (OCPs) and polychlorinated biphenyls (PCBs), previously investigated in relation to other male reproductive health outcomes. Methods: We conducted a nested case-control study of 33

ObjectiveTo identify factors associated with velopharyngeal competence at 10 years of age in children with cleft palate, and examine the longitudinal development of velopharyngeal competence.DesignRegistry-based cohort study.SettingRegional public care university hospitals in Sweden.ParticipantsA total of 507 children born with a cleft palate with or without cleft lip/alveolus.Main Outcome Measure

This chapter outlines the opportunities and current developments of label-free separation of circulating tumor cell (CTC) from blood cells using acoustophoresis. It describes two platforms that have been developed to enable subsequent evaluation of acoustophoresis in clinical settings. All nucleated cells in suspension flow along a microchannel wherein the cells are exposed to an acoustic field. T

Background: Registry data used to monitor clinical care need to be reliable, and the process for assuring data quality transparent. Here the auditing process of the Swedish quality registry for cardiac disease, SWEDEHEART, is described. Methods: SWEDEHEART audits have been performed at 4 time-points in 2011 to 2018, with data quality audited in the 3 largest subregistries covering acute coronary s