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Synchrotron-radiation nano-X-Ray Fluorescence (XRF) is a cutting-edge technique offering high-resolution insights into the elemental composition of biological tissues, shedding light on metabolic processes and element localization within cellular structures. In the context of Idiopathic Pulmonary Fibrosis (IPF), a debilitating lung condition associated with respiratory complications and reduced li
BACKGROUND: Perfluoroalkyl substances (PFAS) are stable chemicals used in various applications. PFAS exposure has been associated with lower birth weight and immunological effects in children, and limited evidence further suggests adverse neurodevelopmental effects. Previous studies show that PFAS cross the placental barrier during pregnancy leading to prenatal exposure of the fetus. Research on t
Background and objective: There is limited literature on the relationship between cardiovascular health (CVH) and kidney stones. This study aims to compare the association of Life's Simple 7 (LS7) and Life's Essential 8 (LE8) with kidney stone prevalence. Methods: A cross-sectional analysis was conducted utilizing NHANES data (2007–2018). Participants aged ≥20 yr with a history of kidney stones an
Diabetes is an escalating health concern affecting approximately 152.6 million people globally in rural areas, with a significant rise in low- and middle-income countries where over 75% of affected adults live. These populations face unique challenges, including delayed diagnosis, limited access to specialized care, and economic hardships, leading to severe complications such as cardiovascular dis
Introduction: The infarcted heart is energetically compromised exhibiting a deficient production of adenosine triphosphate (ATP) and the ensuing impaired contractile function. Short-term blockade of the protein S100A9 improves cardiac performance in mice after myocardial infarction (MI). The implications upon ATP production during this process are not known. Objectives: This study evaluates whethe
Epilepsy is a chronic neurological disorder marked by recurrent seizures, significantly impacting individuals worldwide. Current treatments are often ineffective for a third of patients and can cause severe side effects, necessitating new therapeutic approaches. Glial cells, particularly astrocytes, microglia, and oligodendrocytes, are emerging as crucial targets in epilepsy management. Astrocytes
This paper aims to explore and conceptualise the marketing work of e-commerce managers. It draws on an ethnographically inspired study involving 21 e-commerce managers and approaches marketing work as a set of socio-material practices. The analysis shows that the marketing work of e-commerce managers centres on assembling, adjusting, and maintaining ‘marketing machines’ – complex market devices de
BACKGROUND: The study aimed to describe all diagnosed cases of Legionnaire's disease (LD) in south Sweden, regarding incidence, patient characteristics, diagnostics, outcomes, and infection control investigations.METHODS: This population-based retrospective study was conducted in Skåne, on patients with LD between 2011-2021. Inclusion criteria were positive polymerase chain reaction (PCR) for L.
BACKGROUND: The impact of the sustainable EAT-Lancet planetary health diet on brain and cognitive health remains unclear. This study compared the impact of the EAT-Lancet diet with the well-established cognitive-beneficial Mediterranean diet (MeDi) in relation to neuroimaging biomarkers and cognitive performance among older adults.METHODS: The study included 615 dementia-free 70-year-olds from the
Introduction: Contrary to popular belief, there is limited research on sugar intake as a risk factor for cardiovascular disease. While the links between sugar-sweetened beverage intake and cardiovascular disease risk are well-established, little is known about the associations for overall added or free sugar intake and other dietary sources of added sugar. Objective markers of habitual sugar intak
The enhancement and protection of coastal ecosystems that sequester carbon for climate change mitigation have developed over the last 15 years, and today are part of climate governance. After an initially challenging start in terms of policy interest, Blue Carbon is now included in some countries’ national inventories, and as such, enters the global sums of emissions and sinks, and becomes relevan
ObjectivesPatient perceived benefit of treatment for cleft lip and/or palate is of great importance since it is central to development of cleft care. CLEFT-Q is a cleft-specific questionnaire on health-related quality of life. Test-retest reliability, aspects of responsiveness and interpretability are yet to be established for CLEFT-Q. This study aims to investigate these psychometric characterist
PURPOSE: Adding salt to foods, a novel indicator for studying habitual sodium intake, has been positively associated with multiple diseases and mortality. However, little is known about its association with liver-related disorders. This study aimed to investigate the associations of adding salt to foods with risks of metabolic dysfunction-associated steatotic liver disease (MASLD), cirrhosis, and
Objective: Screening for abdominal aortic aneurysm (AAA) defined as an infrarenal aortic diameter (IAD) of ≥30 mm reduces mortality, but managing patients with diameters of 25 to 29 mm is debated. Incorporating body surface area into the diagnostic criteria may improve the identification of those at risk of developing treatment-requiring aneurysms in this group. In a previous study, we defined a r
Background: Survivors of stroke commonly report sleep disturbances. Studies of sleep disturbances after stroke are mostly performed in the acute phase. An increased knowledge of sleep disturbances and its determinants a longer time after stroke is needed to improve treatment and rehabilitation. Objective: To assess survivors of stroke more than 1 year after stroke onset and (1) investigate self-re
OBJECTIVES: Health utilities derived from answers to generic health-related quality of life (HRQoL) questionnaires such as the EuroQol 5-Dimensions (EQ-5D) are often used in cost-utility analyses (CUAs) of new and expensive treatments. Different preference sets (tariffs) used in the computation of utility values and quality-adjusted life-years (QALYs) from questionnaire responses (health states) y
