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Organ Specific Killing af a Dispensable Organ or a Cell Population in an Organ - a Successful Design for Cancer Therapy - a Hypothesis

Purpose: This article hypothesizes that designing cancer therapies based on the organ specific toxicity of the normal tissue of the organ from which the tumors originated could be worthwhile. A prerequisite for successful therapy is that the individual can recover from damage done to the organ or cells.Results: Therapeutic examples are given for lymphoma, kidney cancer, melanoma and leukemia.Concl

Mapping the melanoma plasma proteome (MPP) using single-shot proteomics interfaced with the WiMT database

Plasma analysis by mass spectrometry-based proteomics remains a challenge due to its large dynamic range of 10 orders in magnitude. We created a methodology for protein identification known as Wise MS Transfer (WiMT). Melanoma plasma samples from biobank archives were directly analyzed using simple sample preparation. WiMT is based on MS1 features between several MS runs together with custom prote

Schlafen2 is a regulator of quiescence in adult murine hematopoietic stem cells

Even though hematopoietic stem cells (HSC) are characterized by their ability to self-renew and differentiate, they primarily reside in quiescence. Despite the immense importance of this quiescent state, its maintenance and regulation is still incompletely understood. Schlafen2 (Slfn2) is a cytoplasmic protein known to be involved in cell proliferation, differentiation, quiescence, interferon resp

Intensive care patients with preeclampsia – Clinical risk factors and biomarkers for oxidative stress and angiogenic imbalance as discriminators for severe disease

Background: Approximately 180 mothers are treated in Swedish Intensive Care Units (ICU) due to preeclampsia each year. Although several clinical risk factors are known, prediction of critical disease is challenging. Two scavenger proteins, hemopexin (Hpx) and alpha-1-microglobulin (A1M) have been suggested to be associated with the oxidative stress seen in preeclampsia. The ratio of two other biom

Dynamic User Grouping based on Location and Heading in 5G NR Systems

User grouping based on geographic location in fifth generation (5G) New Radio (NR) systems has several applications that can significantly improve network performance, user experience, and service delivery. We demonstrate how Sounding Reference Signals channel fingerprints can be used for dynamic user grouping in a 5G NR commercial deployment based on outdoor positions and heading direction employ

Out of the tropics : Macroevolutionary size trends in an old insect order are shaped by temperature and predators

Aim: Global interspecific body size distributions have been suggested to be shaped by selection pressures arising from biotic and abiotic factors such as temperature, predation and parasitism. Here, we investigated the ecological and evolutionary drivers of global latitudinal size gradients in an old insect order. Location: Global. Taxon: Odonata (dragonflies and damselflies). Methods: We compiled

Population specific annual cycles and migration strategies in a leap-frog migrant

A common migratory pattern in birds is that northerly breeding populations migrate to more southerly non-breeding sites compared to southerly breeding populations (leap-frog migration). Not only do populations experience differences in migration distances, but also different environmental conditions, which may vary spatiotemporally within their annual cycles, creating distinctive selective pressur

Comorbidities in women with polycystic ovary syndrome : a sibling study

BACKGROUND: Polycystic ovary syndrome (PCOS) has previously been associated with several comorbidities that may have shared genetic, epigenetic, developmental or environmental origins. PCOS may be influenced by prenatal androgen excess, poor intrauterine or childhood environmental factors, childhood obesity and learned health risk behaviors. We analyzed the association between PCOS and several rel

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Advancing rights-based climate adaptation in Armenia’s water sector The right to water Advancing rights-based climate adaptation in Armenia’s water sector The right to water Authors: Silva Ayvazyan1, Armine Chakhalyan,2 Mari Chakryan,3 Zaruhi Gharagyozyan,4 Olympia Geghamyan,5 Anush Lokyan,6 Lilit Minasyan,7 Nunufar Stepanyan,8 Arpine Sukiasyan,9 Ani Yeghikian10 Support: Mo Hamza11 and Matthew Sco

https://rwi.lu.se/wp-content/uploads/2025/10/Final-Armenian-Country-Profile-EN.pdf - 2025-12-19

Överslagsdimensionering av fackverksbroar i stål för gång- och cykeltrafik LTH Ingenjörshögskolan vid Campus Helsingborg Institutionen för byggvetenskaper / Byggnadsmekanik Examensarbete: Dawid Rozwadowski Magnus Krysell  Copyright Dawid Rozwadowski, Magnus Krysell LTH Ingenjörshögskolan vid Campus Helsingborg Lunds universitet Box 882 251 08 Helsingborg LTH School of Engineering Lund Uni

https://www.byggmek.lth.se/fileadmin/byggnadskonstruktion/publications/THID/THID3043.pdf - 2025-12-19

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LionSealWhite Lecture 5 LTV stability concepts Quadratic Lyapunov functions Feedback, Well-posedness, Internal Stability Rugh Ch 6,7,12 (skip proofs of 12.6 and 12.7),14 (pp240-247) + (22,23,24,28) Zhou, Doyle, Glover pp 117-124 1 / 31 LionSealWhite Stability For LTI systems ẋ = Ax the stability concept was easy, we had the two concepts i) Stability: x(t) remains bounded ii) Asymptotic stability:

https://www.control.lth.se/fileadmin/control/Education/DoctorateProgram/2019LinearSystem/2019_Linear_System_Lecture_5.pdf - 2025-12-19

Plasticity in Daphnia eye size is determined by intra-generational environmental conditions

Variation in the structure and size of the eye in relation to light environments is well-documented across animal taxa. However, the long-term effects of ultraviolet radiation (UVR) on eye size across generations remain understudied, despite natural fluctuations in UVR being common in aquatic habitats. Here, we used Daphnia magna to test whether an evolutionary history of UVR threat modifies plast

IGFBP1 and IGFBP3 polymorphisms predict circulating IGFBP-3 levels among women from high-risk breast cancer families.

The insulin-like growth factor (IGF) pathway has been implicated as risk modifier in premenopausal breast cancer. In this study, associations between single nucleotide polymorphisms (SNPs) and diplotypes in the IGFBP1 and IGFBP3 genes and circulating IGFBP-3 levels, BRCA family status and breast cancer among women from high-risk breast cancer families were investigated. Nine IGFBP1 and IGFBP3 SNPs

Kondratenko yuri

Introduction LUMES Master Thesis 2002-2003 How Can Systems Thinking Be Used to Support Rural Development Decisions in Latvia Submitted in partial fulfilment of the requirements of the International Master in Environmental Sciences degree, Lund University, Sweden Submitted by: Yuri Kondratenko Ganu 4-10 Riga LV-1010 Latvia Phone: +371 7 33 10 97 jurijs.kondratenko.197@student.lu.se Supervisor: Ande

https://www.lumes.lu.se/sites/lumes.lu.se/files/kondratenko_yuri.pdf - 2025-12-20

Elevations In Blood Glucose Before And After The Appearance Of Islet Autoantibodies In Children.

Elevations in blood glucose before and after the appearance of islet autoantibodies in children Katharina Warncke, … , Anette-G. Ziegler, for the GPPAD and POInT Study Groups J Clin Invest. 2022;132(20):e162123. https://doi.org/10.1172/JCI162123. Graphical abstract Research Article Immunology Find the latest version: https://jci.me/162123/pdf http://www.jci.org http://www.jci.org/132/20?utm_campai

https://www.gppad.lu.se/sites/gppad.lu.se/files/2022-12/Elevations%20in%20blood%20glucose%20before%20and%20after%20the%20appearance%20of%20islet%20autoantibodies%20in%20children..pdf - 2025-12-20

Kommentarmaterial Till Kursplanen I Fysik 2022

Kommentarmaterial till kursplanen i fysik Skolverket publikation Kommentarmaterial till kursplanen i fysik Grundskolan K O M M E N T A R M A T E R IA L Publikationen finns att ladda ner som kostnadsfri PDF från Skolverkets webbplats: www.skolverket.se/publikationer ISBN: 978-91-7559-386-9 Skolverket, Stockholm 2021 http://www.skolverket.se/publikationer 3 KOMMENTARMATERIAL TILL KURSPLANEN I FYSIK

https://www.nrcf.lu.se/sites/nrcf.lu.se/files/2024-09/Kommentarmaterial%20till%20kursplanen%20i%20fysik%202022.pdf - 2025-12-20