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Osteoblasts, osteocytes, and osteoclasts (OCs) are involved in the bone production and resorption, which are crucial in bone homeostasis. OC hyperactivation plays a role in the exaggerated bone resorption of diseases such as osteoporosis, rheumatoid arthritis, and osteolytic tumor metastases. This work stems from the finding that OCs can express B7h (ICOS-Ligand), which is the ligand of the ICOS T
Ten years after its introduction, equity in human papillomavirus (HPV) vaccine uptake remains unattained, not least for the groups at highest risk of cervical cancer. In Sweden, three different delivery modes of the vaccine have been in effect since May 2007. We used this as a natural experiment to investigate girls’ HPV vaccine uptake in relation to parental country of birth and socioeconomic cha
Lägg till titel Page 1 of 1 REGULATORY DOCUMENT COVER PAGE Quality Policy for Lund University Type of regulatory document: Policy Definition of the type of regulatory document: Policies express the management’s overall intended direction or values that are to be taken into account within the area covered by the policy, set frameworks for a specific course of action and constitute a strong recommen
https://www.staff.lu.se/sites/staff.lu.se/files/2025-02/quality-policy-for-lund-university.pdf - 2026-07-17
Humans have developed a system of mass production just recently if you compare to Nature’s industry, which has dealt with if for about 3,8 billion years. In some aspects these two systems do not follow the same rules even though we share the same location. Move on is a project that mainly rases the fact that some human products live too long for their made purpose. Life is a state that also includ
Eight Brides for Twenty-Four Brothers Four Brides for Twelve Brothers: How to Dutch Book a Group of Individually Rational Players 1 Luc Bovens London School of Economics and Political Science Dept. of Philosophy, Logic and Scientific Method L.Bovens@LSE.ac.uk You can’t be wise and in love at the same time. (Bob Dylan) Abstract. Wlodek Rabinowicz suggested in an e-mail conversation (2001) to me tha
https://www.fil.lu.se/hommageawlodek/site/papper/BovensLuc.pdf - 2026-07-17
AIMS: Women who deliver pre-term have higher future risks of hypertension and ischaemic heart disease, but long-term risks of heart failure (HF) are unknown. We examined these risks in a large national cohort.METHODS AND RESULTS: All 2 201 284 women with a singleton delivery in Sweden during 1973-2015 were followed up for inpatient or outpatient HF diagnoses through 2015. Cox regression was used t
Objective: This study examined how patterns of repetitive (≥5 instances) nonsuicidal self-injury (NSSI) associate with measures of resilience and life events retrospectively reported to have occurred within the last year, 1 to Method: Life events reported by 557 young adults (mean [SD] age 25.3 [0.68]; 59.2% women) were classified as positive, negative, or profoundly negative based on their relati
Introduction: The inspiratory flow pattern influences CO2 elimination by affecting the time the tidal volume remains resident in alveoli. This time is expressed in terms of mean distribution time (MDT), which is the time available for distribution and diffusion of inspired tidal gas within resident alveolar gas. In healthy and sick pigs, abrupt cessation of inspiratory flow (that is, high end-insp
Objective To avoid ventilator induced lung injury, tidal volume should be low in acute lung injury (ALI). Reducing dead space may be useful, for example by using a pattern of inspiration that prolongs the time available for gas distribution and diffusion within the respiratory zone, the mean distribution time (MDT). A study was conducted to investigate how MDT affects CO2 elimination in pigs at he
Inherited retinal degeneration (RD) is a devastating and currently untreatable neurodegenerative condition that leads to loss of photoreceptor cells and blindness. The vast genetic heterogeneity of RD, the lack of “druggable” targets, and the access-limiting blood–retinal barrier (BRB) present major hurdles toward effective therapy development. Here, we address these challenges (i) by targeting cG
In boron neutron capture therapy (BNCT) the absorbed dose to the tumor cells and healthy tissues depends critically on the boron uptake. Pronounced individual variations in the uptake patterns have been observed for two boron compounds currently used in clinical trials. This implies a high uncertainty in the determination of the boron dose component. Ln the present work a technique known as prompt
Excited states in the proton drip line nucleus 61Ga were populated via the fusion-evaporation reaction 24Mg(40Ca,p2n)61Ga. The experimental setup at Argonne National Laboratory comprised a novel combination of the Gammasphere array with two CD-shaped double-sided Si-strip detectors inside the Microball CsI(Tl) charged-particle detection array, as well as the Neutron-Shell liquid scintillators and
