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Dyskinesias are a major complication of long-term l-3,4-dihydroxyphenylalanine (L-DOPA) treatment in Parkinson's disease, and are believed to result from the intermittent and pulsatile supply of L-DOPA. Daily injections of L-DOPA can prime similar abnormal involuntary movements of the limb, orolingual and axial muscles in rats rendered parkinsonian by destruction of the nigrostriatal dopamine (DA)
Streptococcus pyogenes is one of the most common bacteria infecting humans. One of the factors contributing to the disease-causing properties is the secreted streptococcal cysteine proteinase, SpeB, which degrades several host proteins in connective tissue and circulation. SpeB activity depends on the transformation from an inactive precursor, zymogen, into a mature proteinase. We show that
Streptococcus pyogenes (Group A streptococcus; GAS) is an important human pathogen responsible for mild to severe, life-threatening infections. GAS expresses a wide range of virulence factors, including the M family proteins. The M proteins allow the bacteria to evade parts of the human immune defenses by triggering the formation of a dense coat of plasma proteins surrounding the bacteria, includi
Objective: To assess available evidence on the use of end-points ( outcome measures) in clinical trials in systemic lupus erythematosus (SLE), as a part of the development of evidence-based recommendations for points to consider in clinical trials in SLE. Methods: The European League Against Rheumatism (EULAR) Task Force on SLE comprised 19 specialists, a clinical epidemiologist and a research fel
Iron oxide nanoparticles are involved in several important biogeochemical processes. The interfaces between aqueous solutions and iron oxide nanoparticle surfaces are found everywhere in nature, and the chemical and microbial processes occurring at these complex interfaces control e.g. nutrient and contaminant availability and transport. Recently, it has been shown that certain ectomycorrhizal (EC
Institutionen för handelsrätt Uppd: 2024-02-09 Tentamensschema februari 2024 - augusti 2024 Datum Kurskod Kursnamn Tid Lokal Tors 1 feb HARG06 Arbetsrätt II, Dugga 8-10 MA9 Ons 7 feb HARN53 Trade, Investment and Sustainability 8-13 EC2:063 HARN54 Intellectual Property and Trade Ons 28 feb HARA71 Kommersiella avtal och köp 8-13 MA8 HARG15 Compliance och risk i affärslivet HARG03 Kommersiell avtalsr
11 september 2025 08:30 till 13:00 | Konferens Ekonomihögskolan och Hållbarhetsforum bjuder in till en hubb för den digiloga hållbarhetskonferensen A Sustainable Tomorrow!Årets tema är: Mobilisera med mod och mångfald. I en tid när hållbarhetsutmaningarna är större än någonsin är samarbete avgörande. Därför är vi stolta över att samarbeta med A Sustainable Tomorrow för att ta årets tema på allvar:
https://www.medarbetarwebben.lu.se/evenemang/sustainable-tomorrow-2025 - 2026-07-24
The blood/plasma protein biomarker profile represents the pathological and physiological changes relating to human diseases. However, the plasma proteome reflects a high degree of complexity that results in a challenge for most analytical methods in clinical diagnostics. The focus in this thesis is the development and application of several integrated platforms to detect already established protei
Institutionen för handelsrätt Uppd: 2024-01-22 Tentamensschema februari 2024 - augusti 2024 Datum Kurskod Kursnamn Tid Lokal Tors 1 feb HARG06 Arbetsrätt II, Dugga 8-10 MA9 Ons 7 feb HARN53 Trade, Investment and Sustainability 8-13 EC2:063 HARN54 Intellectual Property and Trade Ons 28 feb HARA71 Kommersiella avtal och köp 8-13 MA8 HARG15 Compliance och risk i affärslivet HARG03 Kommersiell avtalsr
Institutionen för handelsrätt Uppd: 2024-02-28 Tentamensschema februari 2024 - augusti 2024 Datum Kurskod Kursnamn Tid Lokal Tors 1 feb HARG06 Arbetsrätt II, Dugga 8-10 MA9 Ons 7 feb HARN53 Trade, Investment and Sustainability 8-13 EC2:063 HARN54 Intellectual Property and Trade Ons 28 feb HARA71 Kommersiella avtal och köp 8-13 MA8 HARG15 Compliance och risk i affärslivet HARG03 Kommersiell avtalsr
Objective: To describe the short- and long-term outcomes of infants with early-onset fetal growth restriction (FGR) and umbilical artery absent or reversed end-diastolic flow (AREDF), delivered before 30 weeks' gestation and managed proactively. Methods: This was a retrospective cohort study of fetuses delivered for fetal indication before 30 completed weeks' gestation that had early-onset FGR (de
This paper addresses the issue of coalescence of frequent collocations and its consequences for their realization and mental representation. The items examined are ‘semi-modal’ instantiations of the type V-to-Vinf, namely have to, used to, trying to and need to, in American English. We explore and compare their realization variants in speech, considering the effects of speech-internal and extra-li
