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This study aimed to engineer and characterize a series of Amelogenin-ELP fusion proteins to explore their potential as biomaterials with enhanced properties. Eleven constructs (176-186) were designed and expressed in E. coli BL21(DE3) cells, with successful purification confirmed by SDS-PAGE. Dynamic Light Scattering (DLS) revealed that constructs 181, 185, and 186 formed nanospheres similar to fu
This Master Thesis describes the mathematical modeling of a Delta-3 robot actuated by motors and drive units developed by ELAU GmbH. A given model of the ELAU GmbH drive unit and motor is used when building the Delta-3 robot model including three drive units, one for each motor to be able to actuate the three upper arms. The Delta-3 robot model is divided into kinematics and dynamics parts. The ki
In dealing with calorimetry, safety aspects are very important. It is therefore very useful to be able to study a process before carrying out experiments on it. A computer model can then be very useful to save time and money. The purpose of this thesis was to construct a computer model of the Chemisens reaction calorimeter, in the modeling software Dymola. For the purpose of the modeling, a new Dy
Gambro is one of the biggest developers and manufactures of machines for hemodialysis treatments in the world. One component on their machines, the air level detector (ALD), has been identified to have a possibility to be further improved from usability perspective. The ALD is located at the front of the machine and has the function to hold the venous drip chamber in place and detect whether or no
An exploratory study of the forces and actors influencing the marketing of functional foods in Finland and Estonia Empirical example: Fazer Bakery's iLove products
My primary objective in this study was to investigate the impact of the upbringing environment on the development of children’s effortful control and achievement motivation. Twenty-five SOS Children’s Village- and 33 family-raised children reported on achievement motivation, whereas SOS Village and family mothers assessed children’s effortful control along with emotion regulation as an additional
Ultraviolet radiation (UVR), specifically of UVA and UVB, has been associated with the development of both photoaging and photo-carcinogenesis, potentially leading to cancer. The use of sun protection in the form of UV filters is known to minimize these damages. By introducing an enzyme-based sunscreen for daily facial use these damages may be reduced while also providing exfoliation and hydration
This article examines the asymptotic behavior of the Widom factors, denoted Wn, for Chebyshev polynomials of finite unions of Jordan arcs. We prove that, in contrast to Widom’s proposal in Widom (Adv Math 3:127–232, 1969), when dealing with a single smooth Jordan arc, Wn converges to 2 exclusively when the arc is a straight line segment. Our main focus is on analysing polynomial preimages of the i
This article discusses another important class of new compatibilist theories of agency and responsibility, frequently referred to as reactive attitude theories. Such theories have their roots in another seminal essay of modern free-will debates, P. F. Strawson's “Freedom and Resentment” (1962). This article disentangles three strands of Strawson's argument—rationalist, naturalist, and pragmatic. I
Simultaneous digital breast tomosynthesis and mechanical imaging (DBTMI), a novel screening approach, combines anatomic DBT with functional analysis of the stress distribution on the compressed breast by mechanical imaging (MI). Preliminary studies suggest potential to reduce false positive findings. DBTMI requires to align DBT and MI images. In this study, we have analyzed robustness to alignment
This article unpacks the politics of disinformation attribution as deterrence. Research and policy on disinformation deterrence commonly draw on frameworks inspired by cyber deterrence to address the ‘attribution problem’, thereby overlooking the political aspects underpinning attribution strategies in liberal democracies. Addressing this gap and bringing together disinformation studies and the fo
Background: Myocardial perfusion SPECT (MPS) and exercise electrocardiography (Ex-ECG) results are of prognostic importance for short-term follow up duration. However, the value of MPS or Ex-ECG findings for long-term risk assessment is less evident as underlying risk factors for ischemic heart disease (IHD) gain in importance. Objectives: To assess the short- and long-term prognostic value of MPS
There is currently intensive research on the development of biobased polymers as potential alternatives to the environmentally hazardous isocyanate-based polyurethanes. In this context, polythioureas (PTUs) form a particularly attractive target because they can be synthesized by using isothiocyanates, a class of molecules that can be found in nature with expected low toxicity. Herein, a serie
Objectives: Lung squamous cell carcinoma (LUSC) is associated with a poor prognosis and a lack of specific treatment options. The dysregulation of activin A (ActA) has been reported in various malignancies. Herein, we investigated the diagnostic and prognostic significance of ActA in LUSC. Materials and methods: ActA concentrations were measured using ELISA in plasma samples of 128 LUSC patients (
We recently introduced the concept of thermoacoustic streaming in microchannels wherein a thermal field is generated inside an acoustic cavity. The result is a fast and controllable streaming for which the thermal energy is provided either by an LED light source [1], or a laser [2]. While in previous works we have measured this effect at steady state, we now present measurements of the build-up an
