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Rationale: Plasma apolipoprotein (apo)M is mainly associated with high-density lipoprotein (HDL). HDL-bound apoM is antiatherogenic in vitro. However, plasma apoM is not associated with coronary heart disease in humans, perhaps because of a positive correlation with plasma low-density lipoprotein (LDL). Objective: We explored putative links between apoM and very-low-density (VLDL)/LDL metabolism a
The main objective of this investigation is to determine the effect of different physical parameters on the performance of biofilters, treating hydrophobic compounds. In this respect, the effects of irrigation and water content of packings on the removal efficiency of bed in different pollutant loading rates, and gas phase flow rates, is studied. Alpha-pinene, which is produced from variety of ind
Hairy cell leukemia is often reported as a disease of young males. The male predominance is strong, 4:1, but the median age in the Swedish national compulsory cancer registry is similar to that of follicular lymphoma, i.e. 62 years. The overall 6-year survival in the Swedish registry of patients diagnosed since 2000 is 80%, 93% of patients <60 years, and 68% of those >60 years. The yearly risk of
The analysis is focused on attitudes towards nuclear power and public risk perceptions in Sweden and Lithuania. Recent theories of risk-society, reflexive modernization as well as social-psychological approaches are used.
Purpose: According to the World Health Organization (WHO), hearing loss (HL) affects up to 15% of the world’s adult population. Coping and personality are hypothesized to underlie quality of life (QoL) and distress scores. We aimed to study the importance of personality and coping in persons with HL for self-reported hearing disability, QoL, and distress. Methods: A cross-sectional survey was carr
Solid-state klystron modulators are typically based on oil-immersed high-voltage (HV) pulse transformers because of their high performance, robustness, simplicity, and straightforward design. However, pulse transformer size is fundamentally linked to application pulse length, pulse power, and pulse rise time. For high-power applications transformer size quickly becomes very problematic when approa
ApoE is a well-known lipid-binding protein that plays a main role in the metabolism and transport of lipids. More recently, apoE-derived peptides have been shown to exert antimicrobial effects. Here, we investigated the antibacterial activity of apoE using in vitro assays, advanced imaging techniques, and in vivo mouse models. The formation of macromolecular complexes of apoE and endotoxins from G
The core of this Doctoral thesis is mainly based in the studies of one-dimensional initial-boundary value problems, which are given by a single non-linear hyperbolic partial differential equation (PDE) with non-convex flux function, or by a system of strongly degenerate parabolic PDEs, for the simulation of sedimentation processes of solid particles immersed in a fluid. Particular attention is pai
Priming mice with a chicken gamma globulin (CGG) carrier protein significantly accelerated the onset of somatic mutation in the V chi Ox1 gene when the mice were subsequently immunized with 2-phenyl-5-oxazolone (phOx) coupled to CGG. The first mutations were already detected 7 days after immunization, while in the true primary response, they are not apparent until day 10. It was also found that co
Aims: The HERMES (HEart failure Molecular Epidemiology for Therapeutic targetS) consortium aims to identify the genomic and molecular basis of heart failure. Methods and results: The consortium currently includes 51 studies from 11 countries, including 68 157 heart failure cases and 949 888 controls, with data on heart failure events and prognosis. All studies collected biological samples and perf
Effect of aluminium on microstructure and properties of austenitic heat resistant steel was investigated. The results showed that Al addition led to formation of spheroidal and dispersed Ni3Al. After solution treatment, Ni3Al particles experienced a significant refinement from 1.5 μm to nanoscale (∼80 nm). Matrix transformed from austenite to ferrite when addition of Al was >4.72%. Oxidation resis
The wheel-rail system operates in an open environment where the weather condition varies constantly. In this laboratory study, an investigation using a pin-on-disc tribometer placed in a temperature-controlled room was conducted to examine the effect of subzero temperature and snow on friction and wear at the wheel-rail contact. In temperature range from 3 to-15 °C (without snow) friction and wear
Burr formation is a problematic aspect in the machining of ductile metals. Understanding the formation mechanism and being able to model the plastic workpiece behavior during tool exits is key to burr minimization. A 3D finite element model is used to simulate burr formation during the exit phase of intermittent turning of AISI 4140, using a nose radiused insert. The model is validated by experime
