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Climate change pushes species toward higher latitudes and altitudes, but the proximate drivers of range expansions vary, and it is unclear whether evolution facilitates climate change–induced range changes. In a temporally replicated field experiment, we trans-located wall brown butterflies (Lasiommata megera) descending from range interior and range margin populations to sites at 1) the range int

This study utilizes a novel analytical framework to examine large-scale development-focused scholarship programs for international higher education. The Indonesia Endowment Fund for Education (LPDP) is systematically analyzed here utilizing its 2013–2022 annual reports. Applying the orders of worth approach, LPDP’s claims and justifications towards the common good are studied, alongside the organi

This chapter is a micro-sociological exploration of the justifications that Danish general practitioners adopt to support antibiotic usage in their clinical practices. Based on qualitative in-depth interviews with 21 general practitioners in Denmark, the chapter looks upon the clinic as a particular social world (a justificatory regime) in which different antibiotic treatment strategies are qualif

Objectives: To investigate: (i) changes in sick-leave benefits from 1 year prior to multimodal rehabilitation to 1 and 2 years after rehabilitation; (ii) sex differences in sick leave; and (iii) the impact of policy changes on sick leave. Methods: All patients undergoing multimodal rehabilitation registered in a national pain database for 2007–11 (n?=?7,297) were linked to the Swedish Social I

Background: Self-reported smoking is the principal measure used to assess lung cancer risk in epidemiological studies. We evaluated if circulating cotinine-a nicotine metabolite and biomarker of recent tobacco exposure-provides additional information on lung cancer risk. Methods: The study was conducted in the Lung Cancer Cohort Consortium (LC3) involving 20 prospective cohort studies. Pre-diagnos

In a costal aquifer, saltwater intrusion is frequently observed due to an excess exploitation. There are many researches focused on the saltwater intrusion. However, there are few researches, which take into consideration the mixing processes in a stratified heterogeneous aquifer. In the present study, a laboratory experiment and numerical simulation are made in order to understand the phenomena i

The aggregation of the amyloid-β (Aβ) peptide is linked to the pathogenesis of Alzheimer’s disease (AD). In particular, some point mutations within Aβ are associated with early-onset familial Alzheimer’s disease. Here we set out to explore how the physical properties of the altered side chains, including their sizes and charges, affect the molecular mechanisms of aggregation. We focus on Aβ42 with

Aims: Chronic left atrial enlargement (LAE) increases the risk of atrial fibrillation. Electrocardiogram (ECG) criteria might provide a means to diagnose LAE and identify patients at risk; however, current criteria perform poorly. We seek to characterize the potentially differential effects of atrial dilation vs. hypertrophy on the ECG P-wave. Methods and results: We predict effects on the P-wave

Although the projected changes in the climate include considerable uncertainties, especially with downscaling, there is irrefutable evidence that the climate is changing at an unprecedented and alarming rate. In recent studies, some of the potential climate-change risks on bridges have been identified. The sheer number of these potential risks provokes two questions. Firstly, for a certain risk of

Context Symptom relief is a key goal of palliative care. There is a need to consider complexities in symptom relief patterns for groups of people to understand and evaluate symptom relief as an indicator of quality of care at end of life. Objectives The aims of this study were to distinguish classes of patients who have different symptom relief patterns during the last week of life and to identify

In this work, we numerically study a self-guiding process in which ionization plays a dominant role and analyze its effect on high-order harmonic generation (HHG) in gases. Although this type of self-guiding-termed "plasmacore- induced self-guiding" in previous works-limits the achievable cutoff by regulating the intensity of the laser beam, it provides favorable conditions for phase matching, whi