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Background: The number of people with cognitive impairment, including dementia, in the world is steadily increasing. Although the consumption of isoflavones and soy is associated with a reduced risk of cardiovascular disease, it might also be associated with cognitive impairment. The low number of studies investigating the association between soy/isoflavone intake and cognitive function warrant ad
In this essay the media depictions of the funeral of the former Swedish prime minister Karl Staaff in 1915 are investigated. It shows that, in a pre-democratic state such as early twentieth-century Sweden, media events did not necessarily voice a hegemonic ideology or harmonious sense of community spirit. Rather, mediated public space, even at the commemoration of a former prime minister, could be
Enabling techniques for separating target cells, such as subgroups of white blood cells and cancercells from blood and other body fluids, are necessary for lab work facilitation, inline integration withhigh-end bioanalytical instrumentation, and for point-of-care or home testing. The work of this thesisaddresses this need by further studying an equilibrium-based ultrasonic wave-based technology ca
Data clustering is considered an important component of data mining which aims to split a given dataset into disjoint groups having the same similarities. The developed techniques for clustering have some challenges to cluster entities in complex search space and most of them aim to maximize the sum of inter-cluster distances and minimize the sum of intra-cluster distances. This objective function
During our 15 months of ethnographic fieldwork in Russia from January 2014 through November 2019, we traveled extensively within Moscow, running from one side of the city to another in search of informants.
Selective autophagy of the endoplasmic reticulum (ER), namely ER-phagy, is mediated by ER-localized receptors, which are recognized and sequestered by GABARAP/LC3B-decorated phagophores and transferred to lysosomes for degradation. Being one such receptor, FAM134B plays critical roles in cellular processes such as protein quality control and neuronal survival. FAM134B has also been associated with
Bio-based and patient-specific three-dimensional (3D) scaffolds can present next generation strategies for bone tissue engineering (BTE) to treat critical bone size defects. In the present study, a composite filament of poly lactic acid (PLA) and 45S5 bioglass (BG) were used to 3D print scaffolds intended for bone tissue regeneration. The thermally induced phase separation (TIPS) technique was use
Ambisonics fixed media composition. 2020. 14:00. PLEASE NOTE this is a Headphone version. It will not play properly in speakers. Multi-channel speaker versions of the piece are available from the composer on request.
Europe's relationships with the rest of the world have been, and will be, of crucial importance to understanding the changing nature of global politics and Europe's place on a globalisaing planet. In this chapter we will attempt to explore and explain these relationships froma variety of viewpoints as we consider the links between Europe and the world from fifteenth-century sea travel to twenty-fi
The tenth-century Byzantine hagiographical Life of Theoktiste, written by Niketas Magistros, has been read in various ways, not in the least intertextually and as the life of a non-existing saint. The present article further investigates the motives of the author, the social and cultural vision, as well as generic notions, embedded in the text, and offers a new date of composition for the Life, vi
This article is the concluding essay of the Western and Northern Europe volume of Edinburgh University Press's series on Global Christianity.
The self-assembly of inorganic nanoparticles is a research area of great interest aiming at the fabrication of unique mesostructured materials with intrinsic properties. Although many assembly strategies have been reported over the years, chemically induced self-assembly remains one of the dominant approaches to achieve a high level of nanoparticle organization. In this feature article we will rev
Loss and damage is the “third pillar” of international climate governance alongside mitigation and adaptation. When mitigation and adaptation fail, losses and damages occur. Scholars have been reacting to international political discourse centred around governing actual or potential severe losses and damages from climate change. Large gaps exist in relation to understanding the underlying power di
Bomb pulse refers to the sharp increase of the atmospheric levels of the carbon isotope 14C due to nuclear testing during the late 1950s and early 1960s. After the nuclear test ban, atmospheric 14C levels decreased exponentially because of the diffusion and equilibration with the ocean and biosphere, as well as the incorporation indirectly into all living cells. Thus, assessing the anthropogeni
The ubiquitin (Ub) kinase-ligase pair PINK1-PRKN mediates the degradation of damaged mitochondria by macroautophagy/autophagy (mitophagy). PINK1 surveils mitochondria and upon stress accumulates on the mitochondrial surface where it phosphorylates serine 65 of Ub to activate PRKN and to drive mitochondrial turnover. While loss of either PINK1 or PRKN is genetically linked to Parkinson disease (PD)
We study the geometric significance of Leinster’s notion of magnitude for a compact metric space. For a smooth, compact domain X in an odd-dimensional Euclidean space, we show that the asymptotic expansion of the function MX(R) = Mag(R·X) at R = ∞ determines the Willmore energy of the boundary ∂X. This disproves the Leinster-Willerton conjecture for a compact convex body in odd dimensions.
Here, an acoustophoresis chip is presented that is capable of separating cancer cells from white blood cells (WBCs) and subsequently concentrating the recovered cells in the same chip. The chip utilizes ultrasound standing waves in two dimensions to pre-align, separate and concentrate the cells. 92% of the cancer cells could be recovered while keeping the contamination level of WBCs to only 0.6%.
