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The aim of this study is to understand the mechanisms behind the diffusion of fired bricks in Hellenistic Europe, initiated in the north Aegean in the 4th century BC. To this end, a social diffusion model is used to simulate the available archaeological data pertaining to this process. The starting point in the construction of the model is the assumption that different categories of people contrib

Background: Malignant melanoma and non-melanoma skin cancers are among the fastest increasing malignancies in many countries. With the help of new tools, such as teledermoscopy referrals between primary health care and dermatology clinics, the management of these patients could be made more efficient. Objective: To evaluate the diagnostic agreement and interobserver concordance achieved when asses

There is an increasing demand for real world evidence. The shift towards relative effectiveness assessment increasingly based on real world data is a natural consequence of the shift towards new adaptive pathways for development and introduction of new medicines in cancer care. The increasing number of alternative treatment options will further increase the need for outcomes data to help optimize

STUDY DESIGN: Cross-sectional. BACKGROUND: The association between muscle function and lack of knee confidence in people with anterior cruciate ligament (ACL) injury has not been well investigated. Such knowledge would help in the design of training programs for this population. OBJECTIVE: To investigate associations between self-reported knee confidence and muscle function in patients with ACL in

At a time when rapidly evolving technologies, political turmoil, and the tensions inherent in multiculturalism and globalization are reshaping historical consciousness, what is the proper role for historians and their work? By way of an answer, the contributors to this volume offer up an illuminating collective meditation on the idea of ethos and its relevance for historical practice. These intell

Can financial institutions and markets enhance the discipline imposed by competitive product markets and thus improve resource allocation in the real economy? We address this question in the context of international trade, using disaggregated product-level data from 71 countries exporting to the USA. We show that exported products exit the US market sooner if they stand far away from the exporting

As a result of advances in healthcare and rehabilitation, many people with spinal cord injury (SCI) have lived several decades with their injury. Knowledge of living with long-term SCI into older age is limited, despite an increased focus on aging with SCI in research and clinical practice.The overarching aim of this thesis was to describe and understand the life situation of older adults with lon

MicroRNAs (miRNAs) are cellular, short, non-coding ribonucleotides acting as endogenous posttranscriptional repressors following incorporation in the RNA-induced silencing complex. Despite being chemically and mechanistically very similar, miRNAs exert a multitude of different cellular effects by acting on mRNA species, whose gene-products partake in a wide array of processes.Here, the aim was to

The goal of this study has been to establish a method for quantifying the minimum chip thickness, h1min, during longitudinal turning of duplex stainless steel, and explore how the value of h1min changes with varying process parameters. Based on experimental results, it was found that the tool edge radius only has a limited influence on the size of h1min up to a certain feed level after which the c

This paper provides a consistent series for the Irish national debt since the foundation of the state. It also provides a continuous series for bond yields over the same period. The paper examines the factors behind the fluctuations in the debt burden over almost a century. The management of the debt burden by the Irish authorities has evolved over time, seeking to minimise both the burden on the

Fatigue is one of the principal damage mechanisms in a slender concrete structure under cyclic loads. And needs to be calculated locally through all the structure, considering the lading conditions and the particularities of concrete. The model presented here is capable to account for the fatigue damage in a probabilistic way, relating the annual loading conditions for each point and the degradati

Inspections are an efficient means of enhancing the reliability of redundant structural systems subjected to fatigue.To investigate the effect of such inspections, we represent the deterioration state of a Daniels system by means of a probabilistic fatigue crack growth model of all elements, which considers stochastic dependence among element fatigue behavior. We include inspection results in the

Background: Outcome measures can be used to improve the quality of the rehabilitation by identifying and understanding which variables influence the outcome. This information can be used to improve outcomes for clients. In clinical practice, pure-tone audiometry, speech reception thresholds (SRTs), and speech discrimination scores (SDSs) in quiet or in noise are common assessments made prior to he

The objective of this article reflects upon the isomorphic relationship between ideas across disciplines. In this instance we are considering the value of a well established methodology, cross methodology, adopted from macroeconomics and ideas from political science. The cross methodology is used as a means of considering the relationship between data collected for security purposes and individual

To compare the effectiveness of individual support, group rehabilitation and a combination of the two in improving health-related quality of life (HRQOL) and psychological well-being in cancer patients during 24 months after diagnosis, as compared with standard care (SC). Furthermore, to compare the study sample and a random sample of the Swedish population with regard to HRQOL. A total of 481 con