Filetype
G-protein coupled receptors (GPCRs) regulate hormone secretion from islets of Langerhans, and recently developed therapies for type-2 diabetes target islet GLP-1 receptors. However, the total number of GPCRs expressed by human islets, as well as their function and interactions with drugs, is poorly understood. In this review we have constructed an atlas of all GPCRs expressed by human islets: the
Environmental risk factors, particularly tobacco smoking, are important for transitional-cell carcinoma of the bladder. Studies in migrants may provide valuable insight into the environmental and genetic etiology of cancer. The nationwide Swedish Family-Cancer Database was used to calculate standardized incidence ratios (SIRs) for transitional-cell carcinoma among the immigrants compared with nati
Many bacterial pathogens have developed methods to overcome the defences of the host innate immune system. One such defence is the release of antimicrobial peptides (AMPs). Histones have been found to function as AMPs, in addition to their main biological function of packaging and organising DNA into nucleosomes. In this study, the Gram-positive anaerobic coccus Finegoldia magna was found to bind
Objective: assess the effect of clinical vertebral and other osteoporotic fractures on function and the subsequent risk of hospitalisation. Design: individuals from the prospective population-based cohort study Age, Gene/Environment Susceptibility (AGES)-Reykjavik study were examined between 2002 and 2006 and followed up for 5.4 years. Subjects: a total of 5,764 individuals, 57.7% women, born 1907
To examine the association of sialic acid (SA) with first recorded diabetes mellitus-related hospitalization.
While the theoretical description of population transfer subsequent to electronic excitation in combination with a line shape function description of vibrational dynamics in the context of 2D-spectroscopy is well-developed under the assumption of different timescales of population transfer and fluctuation dynamics, the treatment of the interplay between both kinds of processes lacks a comprehensiv
In this study, Raman spectroscopy has been used to evaluate the evolution of the structural modification of soot during oxidation processes at various preset temperatures up to 700 °C. Two types of well-characterized mini-CAST soot, representing black soot and brown soot, were examined. The major difference between the signals from the two types of soot was the higher photoluminescence (PL) signal
The aim of this WaterWarmth project Work Package 6.1 report is to present a number of relevant frameworks available to analyse and/or assess the governance of current heating systems and future energy system innovation, in particular with a focus on aquathermal energy (AE) systems. At the basis of the report was a broad survey of the academic and other literature by project researchers on ways to
Quantification of in vivo proton magnetic resonance spectra (1H-MRS) still commonly involves evaluation of exclusively the real part of acquired spectral signals, but ignoring the information contained in the imaginary component may limit precise identification of individual metabolite contributions. Here, we assess quantification precision relative to SNR and noise correlation for both real and c
The gene encoding uridine diphosphate glucuronosyltransferase (UGT) 1A4 shows considerable polymorphism. Several common drugs are metabolised by UGT1A4, among them lamotrigine (LTG). Experimental and clinical studies suggest that certain variants of UGT1A4 are associated with altered enzyme activity. However, results are conflicting. This clinical study aimed to investigate the frequencies of two
A combination of fifteen top quark mass measurements performed by the ATLAS and CMS experiments at the LHC is presented. The datasets used correspond to an integrated luminosity of up to 5 and Formula Presented of proton-proton collisions at center-of-mass energies of 7 and 8 TeV, respectively. The combination includes measurements in top quark pair events that exploit both the semileptonic and ha
Denna studie ämnar undersöka studenters upplevelser av kommunikation under en Zoom-föreläsning. Under den globala pandemin under vintern 2020 valde många universitet att förflytta utbildningen till distans för att förhindra spridningen av viruset covid-19. Detta ökade användningen kraftigt av digitala kommunikationsverktyg, där Zoom kom att bli ett av de primära verktygen. Genom att undersöka komm
This thesis’ focus will be on the comic book series Locke & Key in a semiotic and an intertextual reading through a psychoanalytical framework. The comic series is described as a “psychological horror” and a main theme running across the six volumes is good versus evil, and a lot of the narrative is helped by magical keys. The keys have specific uses and help both sides gain more power. The ps
A new era – but Aurelius can show the way Hoppa till huvudinnehåll Vi använder cookies och andra spårningsteknologier för att förbättra användarupplevelsen på vår webbplats, för att visa dig personligt innehåll och riktade annonser och för att analysera vår webbplatstrafik. Läs mer om cookies. Absolut nödvändiga cookies Dessa cookies är nödvändiga för att webbplatsen ska fungera och kan inte stäng
https://www.lth.se/article/a-new-era-but-aurelius-can-show-the-way/ - 2026-07-10
Though established as a movement and recognised as artistic form, light art remains elusive and somewhat enigmatic in its definitions and categorisations. This thesis aims to contribute to the current discourse on light art by exploring the application of objecthood and embodied simulation whilst acknowledging the contextual, three-dimensional, spectacular, and anti-art qualities of the art form.
More than 500 people die every day from gun violence worldwide. DNA traces may enable the identification of the shooter, but there is limited knowledge concerning where on firearms DNA can be found and how it got there. This project aimed to answer these questions as well as how the swab types and addition of detergents affect the DNA recovery. Three swab types were examined (cotton, nylon flocke
The ancient Kriegsraison doctrine awarded absolute predominance to the achievement of military advantages in armed conflicts and therefore granted the opportunity to secede from all restrictive laws of war. The doctrine was therefore formally condemned as abusive and inconsistent with modern International Humanitarian Law. Especially the contemporary military necessity principle is viewed as a fac
Skyddsrum ska tillgodose civilbefolkningens behov av fysiskt skydd vid väpnat angrepp. Det har inte byggts några nya skyddsrum sedan 2002 men befolkningen har ökat. Totalförsvarsplaneringen har återupptagits med anledning av att den säkerhetspolitiska situationen i Europa har förändrats. Ett väpnat angrepp mot Sverige kan inte uteslutas. Av 3 kap. 9 § MB framgår att de prioriterade områdena för dThe purpose of shelters is to provide protection to the civilian population in case of war. Any new shelters have not been built in Sweden since 2002 but the population has increased. The national defense planning has been resumed because of changes in the security policy situation Europe. War against Sweden cannot be ruled out. According to the 3rd chapter 9 § The Swedish Environmental Code (MB)
