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BACKGROUND: Exposure to toxic methylmercury (MeHg) through fish consumption is a large problem worldwide, and it has led to governmental recommendations of reduced fish consumption and blacklisting of mercury-contaminated fish. The elimination kinetics of MeHg varies greatly among individuals. Knowledge about the reasons for such variation is of importance for improving the risk assessment for MeH
Photosynthetic light harvesting in excess light is regulated by a process known as feedback deexcitation. Femtosecond transient absorption measurements on thylakoid membranes show selective formation of a carotenoid radical cation upon excitation of chlorophyll under conditions of maximum, steady-state feedback deexcitation. Studies on transgenic Arabidopsis thaliana plants confirmed that this car
Introducing a new way of visualizing cDNA microarray data we have identified a new type of systematic variation, which we refer to as plate effects. We believe that plate effects are due to non-biological differences in the cDNA clones products spotted onto the microarray slides. By comparing the consistency of all replicates (both within and between slides) after performing 42 different normaliza
Introduction. We present a prototype collaboratory, a socio-technical platform to support sharing research data collection instruments in library and information science. No previous collaboratory has attempted to facilitate sharing digital research data collection instruments among library and information science researchers. Method. We have taken a socio-technical approach to design, which inclu
Chondroadherin is a cartilage matrix protein that is known to mediate the adhesion of isolated chondrocytes. Its protein core is composed of 11 leucine-rich repeats flanked by cysteine-rich domains at the N- and C-terminal ends. Recombinant human chondroadherin was crystallized using the sitting-drop vapour-diffusion method. The crystals belong to the monoclinic space group P2(1), with unit-cell p
In this thesis, a computational fluid dynamics (CFD) approach is used to study turbulent premixed and partially premixed combustion. The CFD approach is based on large eddy simulation (LES) in which the large-scale structures of the flow are resolved on a grid, leaving only the small-scale structures (subgrid scales) to be modeled. The combustion modelling is based on the flamelet concept in which
In this paper, we evaluate the correlation estimate, based on multiple window spectrum analysis, between the respiratory center frequency and the high-frequency band of the heart- rate variability (HRV) power. One aim is to examine whether a more restricted frequency range would better capture respiratory related HR variation, especially when the HR variation is changing rapidly. The respiratory p
Apolipoprotein M (apoM) is mainly associated with high-density lipoprotein in human plasma. Despite several studies suggesting apoM as an anti-atherogenic, its function is not yet fully understood. Plasma apoM was measured in normal pregnancies at four different gestational ages and in the postpartum period to investigate whether the concentration of apoM changes during pregnancy. In addition, apo
A series of O2 and O3-derivatized methyl beta-d-talopyranosides were synthesized and evaluated in vitro as inhibitors of the galactose-binding galectin-1, -2, -3, -4 (N- and C-terminal domains), 8 (N-terminal domain), and 9 (N-terminal domain). Galectin-4C and 8N were found to prefer the d-talopyranose configuration to the natural ligand d-galactopyranose configuration. Derivatization at talose O2
BACKGROUND: The prevalence of osteoporosis with related fragility fractures has increased during the last decades. As physical activity influences the skeleton in a beneficial way, exercise may hypothetically be used as a prophylactic tool against osteoporosis. OBJECTIVE: This review evaluates if exercise-induced skeletal benefits achieved during growth remain in a long-term perspective. DESIGN: P
A first small set of W III oscillator strengths has been obtained from combined lifetime and branching fraction measurements. The branching fractions in the wavelength region of 154-334 nm were measured with a Penning discharge and a Fourier transform spectrometer. Three levels have been calibrated on absolute scales with lifetimes measured with the time-resolved laser-induced fluorescence techniq
Mandibular autopsy specimens were examined with different radiographic techniques in order to evaluate the visibility of the mandibular canal and the measurement accuracy of distances related to the mandibular canal. Hypocycloidal, spiral and computed tomography (CT) were superior to periapical and panoramic radiography in visualising the mandibular canal. The tomographic techniques were more accu
The GW approximation for the self-energy connected with the one-electron Green's function has been very successful in predicting band structures for a large class of semiconductors and insulators. The physical basis for this approximation and general features of its nonlocality are discussed, as well as possible improvements. Besides quasiparticle energies the self-energy also gives the intrinsic
It is important to know about how frail older people experience their physical decline and how they adapt to their bodily changes so that the health system can design preventive interventions targeting this group early on in the disability process. The aim of this study was to explore how older people perceive their physical decline. The study is qualitative in design and based on interviews with
