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Apomorphine, given subcutaneously (s.c.), induces erection and bladder overactivity in rats through stimulation of dopamine (D1- and D2-like) receptors in the central nervous system. In paraplegic patients, apomorphine was reported to cause bladder overactivity. This suggests that apomorphine may have a spinal site of action also for stimulation of erection. The present study was initiated to eval

The relation between clinical or histologic chorioamnionitis and early neonatal adverse neurologic outcome was investigated (n = 483). Histologic, but not clinical, evidence of chorioamnionitis was found to be a significant predictor of periventricular echodensity (odds ratio, 2.4; 95% CI, 1.8-3.2), echolucency (3.3; 1.9-5.6), ventriculomegaly (2.7; 1.8-4.2), intraventricular hemorrhage > or =3 (3

Background: Giant cell tumour of bone (GCTB) is an osteolytic tumour which contains numerous osteoclast-like giant cells and a proliferation of mononuclear stromal cells (MSC). Giant cell-rich osteolytic lesions can also develop in the jaw bones in Noonan syndrome, a cherubism-like developmental abnormality that is transmitted in an autosomal dominant fashion, often because of mutation in the PTP

Objective. Pancreatic pseudocyst is a common complication of both acute and chronic pancreatitis. The aim of the present study was to evaluate the efficacy and complications of different treatment regimens. Material and methods. All patients >= 15 years of age admitted to Lund University Hospital from 1994 to 2003 with pancreatic pseudocysts were analysed retrospectively. Pseudocysts were defined

Previous publications have shown a high diagnostic sensitivity and specificity of three short clinical rating scales for Alzheimer's disease (AD), frontotemporal dementia (FTD), and vascular dementia (VaD) validated against neuropathological (NP) diagnoses. In this study, the aim was to perform an exploratory factor analysis of the items in these clinical rating scales. The study included 190 pati

Genome-wide association studies (GWAS) have long relied on proposed statistical significance thresholds to be able to differentiate true positives from false positives. Although the genome-wide significance P-value threshold of 5 × 10(-8) has become a standard for common-variant GWAS, it has not been updated to cope with the lower allele frequency spectrum used in many recent array-based GWAS stud

Främsta orsakerna till satsningar på videoövervakningslösningar i detaljhandeln är en vilja att minska oönskade förluster i form av svinn och olika typer av kriminalitet riktad mot butiker. Det visar en studie utförd av forskargruppen Lusax vid Lunds universitet. Studien visar också att den svårtolkade lagstiftningen är ett hinder för bredare användning av videoövervakning.

Background: This study investigates the use of requests for clarification in conversations between teenagers with a cochlear implant (CI) and hearing peers. So far very few studies have focused on conversational abilities in children with CI. Aims: The aim was to explore co-construction of dialogue in a referential communication task and the participation of the teenagers with CI in comparison wit

The introduction of biologics has changed treatment patterns as well as costs in patients with psoriasis. This study was performed to estimate direct and indirect costs of the psoriasis population in Sweden, and to analyse changes in costs between 2006 and 2009. The study population was identified in national registers. Direct costs included health care visits with primary psoriasis diagnoses in s

Primary immunodeficiencies (IDs) are caused by inherited genetic defects leading to intrinsic defects in cells of the immune systems. Most IDs are rare diseases and can be difficult to diagnose because similar symptoms characterize several disorders. Mutation detection is the most reliable method in such cases. These tests are not available at most centers and physicians can have difficulties in f

In internal radionuclide therapy, a growing interest in voxel-level estimates of tissue-absorbed dose has been driven by the desire to report radiobiologic quantities that account for the biologic consequences of both spatial and temporal nonuniformities in these dose estimates. This report presents an overview of 3-dimensional SPECT methods and requirements for internal dosimetry at both regional

The optimal treatment for slipped capital femoral epiphysis (SCFE) remains controversial. In Sweden, the standard treatment is unthreaded fixation over the physis, with the purpose to permit continued growth of the femoral neck. The aim of the present study was to verify and quantify longitudinal growth of the femoral neck after in situ pinning with the Hansson hook-pin.

Accumulating evidence implicates a role for altered metal homeostasis in the pathogenesis of neurodegenerative disorders such as Alzheimer's disease (AD). However, few investigations have addressed this issue in dementia with Lewy bodies (DLB). The aim of the present study was to investigate metal concentrations in cerebrospinal fluid (CSF) and plasma from patients with DLB and other neurodegenera

The effect of the spatial distribution of hydrophobic surface residues on the adsorption of a weakly hydrophobic polymer to proteins has been examined using a coarse-grain model solved by Monte Carlo simulations. A given number of surface sites were distributed randomly on the protein surface subjected to a distance constraint. Five protein classes for which the minimum distance between the sites

A software requirements specification (SRS) is an important document that reports the result from the system requirements determination (SRD) which forms a basis for subsequent activities in the systems development process. In order to increase the knowledge base of SRS and how they could be structured nine SRSs are analyzed. The analysis aims at demonstrate similarities and differences in SRS com

The morphological matrix is an important element of the engineering design methodology and is present in many textbooks. This method originally aimed at generating an exhaustive set of solutions for a given problem, by decomposing it into subproblems, finding solutions to each subproblem, and combining them. One issue associated with the morphological matrix has been the necessity to deal with the

This study is the second part of a larger work with the purpose to distinguish, describe and discuss the discourses around music education in school. The first part focused on how adolescents in secondary school talk abot music education, and the second part is concerned with teaching ideologies and discources among teachers and teacher education students. An overarching purpose of the two studies

Projects with the objective of introducing Finite Element Analysis (FEA) into the early phases of the design process have previously been carried out at the Department of Machine Design, see e.g. the Doctoral thesis by Burman [13]. These works clearly highlight the usefulness of introducing design analysis early in the design process. According to Bjärnemo and Burman [10] the most significant adva