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Purpose: To analyze non-directed parental feedback to health care providers responsible for pediatric cataract care in Sweden. Methods: A directed content analysis was used to analyze data consisting of text representing free comments provided by 40 parents. A deductive approach was employed by applying the model of balancing the child’s inability and ability, which includes the categories masteri

Introduction: The suitability of whole-genome sequencing (WGS) as the sole method to detect clinically relevant genomic aberrations in B-cell acute lymphoblastic leukemia (ALL) was investigated with the aim of replacing current diagnostic methods. Methods: For this purpose, we assessed the analytical performance of 150 bp paired-end WGS (90x leukemia/30x germline). A set of 88 retrospective B-cell

X-ray ptychography is often implemented for nanoimaging at synchrotron radiation sources and extensions are being developed to make experiments faster. This work is on multi-beam ptychography with Fresnel zone plates that have a small lateral separation, enabling the imaging of an extended field of view without increasing exposure time. Sectional zone inversion is implemented for coding respective

Rationale: We recently demonstrated that patients with coronary artery disease (CAD) and obstructive sleep apnea (OSA) carrying the tumor necrosis factor-alpha (TNF-α) A allele had increased circulating TNF-α levels compared with the ones carrying the TNF-α G allele. In the current study, we addressed the effect of TNF-α (-308G/A) gene polymorphism on circulating TNF-α levels following continuous

The importance of older adults’ participation in policymaking is increasingly recognized, but the nuanced participation processes remain insufficiently understood. This scoping review aims to map existing research on older adults’ participation in policymaking, focusing on who participates, their activities and contributions, resulting outputs and outcomes, and the enablers and barriers affecting

Safety is one of the key issues preventing the deployment of reinforcement learning techniques in real-world robots. While most approaches in the Safe Reinforcement Learning area do not require prior knowledge of constraints and robot kinematics and rely solely on data, it is often difficult to deploy them in complex real-world settings. Instead, model-based approaches that incorporate prior knowl

Background T-cell activation and clonal expansion are essential to effective immunotherapy responses in non-small cell lung cancer (NSCLC). The distribution of T-cell clones may offer insights into immunogenic mechanisms and imply potential prognostic and predictive information. Methods We analyzed α/β T-cell receptor (TCR) clonality using RNA-sequencing of bulk frozen tumor tissue from 182 patien

This paper examines prominence from a pragmatic, phonological and acoustic-articulatory perspective. Based on results of a corpus-based analysis of Topic prosodic units in four languages (Italian, Brazilian and European Portuguese, and American English), three types of topic prosodic forms (TPFs) are described. Also are reviewed studies reporting phonological organization of English prominence pat

HYPOTHESIS: Digestion pathways of plant proteins are of high relevance to optimize bioavailability and allergenicity profiles of sustainable and vegan food products. Understanding the structural breakdown of solid food presents a particular challenge, due to the complexity to realize a good model system suitable for comprehensive multi-technique characterization under realistic conditions.EXPERIME

Magic Angle Spinning (MAS) nuclear magnetic resonance (NMR) spectroscopy is limited in spectral resolution by the spinning frequency of rotors that hold the analyte. Traditional yttria-stabilized zirconia (YSZ) rotors have mechanical constraints that typically limit spinning frequencies of 0.7 mm rotors to ωr/2π ∼ 110 kHz. These frequencies are not sufficient to achieve resolution comparable to th

This study investigates the influence of polypropylene fibres (PF) on concrete performance across a finely resolved dosage spectrum (0.0–2.0% by cement mass, in 0.1% increments) using 2,100 laboratory specimens. The experimental programme evaluated compressive strength, tensile strength (flexural and splitting), modulus of elasticity, and water penetration depth. Predictive modelling was conducted

Transition to a circular plastic economy requires rethinking of the entire value chain from the raw materials and energy used for production, to material design, collection and recycling. Our focus has mainly been on polyesters as they span a wide scope of applications and properties ranging from durable to biodegradable. This presentation will highlight our work on designing and developing the bi

Purpose - Explore how pioneer brands use their year of establishment (YoE) as part of their heritage communication, and the level to which they do so. Design and Methodology - Analyze 12 cases of pioneer brands to understand the circumstances of when they use their heritage and the patterns that emerge. Findings - Our cross-case analysis and use of secondary data support our hypothesis, such that

One of the major causes of dwell time delays is the behaviour of passengers during the alighting and boarding processes, such as an uneven spread of boarding passengers and queues formed in front of the doors. Therefore, changing the behaviour of passengers so that it does not negatively affect the time needed for alighting and boarding is one of the ways to reduce the risk of dwell time delays. P

Background: The study aimed to analyze thyroid-stimulating hormone (TSH) levels quantitatively and investigate their potential correlation with the risk of incident atrial fibrillation (AF) in differentiated thyroid cancer (DTC) patients. Methods: DTC cases diagnosed between 1995 and 2015 in Stockholm, Sweden, were identified from the Swedish Cancer Registry. Medical records were scrutinized, and

Dust is essential to the evolution of galaxies and drives the formation of planetary systems. The challenge of inferring the origin of different pre-solar dust grains from meteoritic samples motivates forward modelling to understand the contributions of low- and high-mass stars to dust in our Solar system. In this work we follow the evolution of dust with tracer particles within a hydrodynamical s

Tattoo ink on the European market has been reported to contain many human toxicants, which has raised concerns about health effects. Clarifying the exposure distribution in the population is key to understanding potential public health implications. We investigated the prevalence of tattoos in a population-based Swedish cohort of 13 046 individuals aged 20–68 years with exposure data collected thr