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Matched versus Haploidentical Hematopoietic Stem Cell Transplantation as Treatment Options for Primary Immunodeficiencies in Children : Matched and Haploidentical HSCT in PID

Primary immunodeficiencies (PIDs) are inherited disorders of the immune system with allogeneic hematopoietic stem cell transplantation (HSCT) as the only curative treatment in some of them. In case an HLA-matched donor is not available, HSCT from a haploidentical family donor may be considered. We compared the outcomes of HSCT from HLA-matched unrelated or related donors (MUDs or MRDs) and mismatc

Using sensor-based technology for safety and independence – the experiences of people with dementia and their families

BackgroundThe majority of people with dementia prefer to live independently and safely in their own home cared for by their family members. Much effort has been invested in the development of technology, such as sensor‐based networks. Many challenges remain, in particular gaining more knowledge about their experiences and perceived benefits. This study aimed to explore experiences, needs and benef

Grasslands ancient and modern : Soil nutrients, habitat age and their relation to Ellenberg N

Questions: To what extent does the long-term process of grassland succession reflect changes in nutrient availability or other effects of grassland history? Plant communities in ancient, semi-natural pastures include many species associated with nutrient-poor soils. However, semi-natural pasture communities can also develop on previously arable sites — as nutrient levels decline over time. In Euro

Personal networks and crime victimization among Swedish youth

We combine routine activity theory, lifestyle-victimization theory, and a social network perspective to examine crime victimization. In particular, we study to what extent crime victimization is associated with having close contacts who have been victimized and/or who engage in risky lifestyles. We use the data (collected in 2014) of 1,051 native Swedes and 1,108 Iranian and Yugoslavian first- or

In vitro fermentability and antioxidant capacity of the indigestible fraction of cooked black beans (Phaseolus vulgaris L.), lentils (Lens culinaris L.) and chickpeas (Cicer arietinum L.)

BACKGROUND: Pulses represent an important source of protein, as well as digestible and indigestible carbohydrates. Little information is available on the indigestible carbohydrates and antioxidant capacity of legume seeds. The cooked seeds of three pulses (black bean, chickpea and lentil) were evaluated for their indigestible fraction (IF), polyphenols content, antioxidant capacity and in vitro fe

Prevalence of skin disease in a population-based sample of adults from five European countries

Background: There is a lack of prevalence data on skin diseases in the general adult population; most studies have been carried out in small, national or consecutive clinical samples. Objectives: To determine the prevalence of common skin disease in the general European population and to assess differences in the characteristics of treatment between countries. Methods: A random sample consisting o

Multiband modulation spectroscopy for the determination of sex and species of mosquitoes in flight

We present a dual-wavelength polarimetric measurement method to distinguish species and sexes of disease transmitting mosquitoes in flight. By measuring co- and de-polarized backscattered light at 808 and 1550nm, the degree of linear polarization, wingbeat frequency, reflectance, spectral ratio and glossiness of mosquitoes can be retrieved. Body and wing contributions to these signals can be separ

An Improved Spatial Downscaling Procedure for TRMM 3B43 Precipitation Product Using Geographically Weighted Regression

Precipitation data at high spatio-temporal resolution are essential for hydrological, meteorological, and ecological research in local basins and regions. The coarse spatial resolution (0.25°) of Tropical Rainfall Measuring Mission (TRMM) 3B43 product is insufficient for practical requirements. In this paper, a multivariable geographically weighted regression (GWR) downscaling method was developed

The American paediatric evaluation of disability inventory (PEDI). Applicability of PEDI in Sweden for children aged 2.0-6.9 years

The American Paediatric Evaluation of Disability Inventory (PEDI) is a new instrument for evaluating functional performance in disabled children aged 6 months to 7.5 years. It was developed to determine a child's functional capacity and performance in three domains, self-care, mobility and social function, as reflected in scores on three scales: (i) functional skills (current capability in specifi

Sintering of binderless cubic boron nitride and its modification by β-Si3N4 additive for hard machining applications

This study present the results of HP-HT sintering, microstructure, properties, and performance of binderless cBN tool material. Within the investigated sintering temperature range of 1900–2600 °C the optimum was found to be 2200–2300 °C. Lower temperature results in incomplete diffusion bonding between cBN grains, while higher temperature results in high degree of recrystallization of initial stru

Acute manic state with psychotic features in a teenager with autoimmune encephalitis

INTRODUCTION: Autoimmune disorders have become increasingly acknowledged as having a more causative role in encephalitis than previously assumed. Anti-N-methyl-D-aspartate receptor encephalitis seems to be the most prevalent disorder. Symptoms of the neuropsychiatric phase in children and adolescents include abnormal behavior, seizures, and neurologic symptoms. We present a report on a teenage gir

On compositions of special cases of Lipschitz continuous operators

Many iterative optimization algorithms involve compositions of special cases of Lipschitz continuous operators, namely firmly nonexpansive, averaged, and nonexpansive operators. The structure and properties of the compositions are of particular importance in the proofs of convergence of such algorithms. In this paper, we systematically study the compositions of further special cases of Lipschitz c

Quantitative trait loci, G×E and G×G for glycemic traits : response to metformin and placebo in the Diabetes Prevention Program (DPP)

The complex genetic architecture of type-2-diabetes (T2D) includes gene-by-environment (G×E) and gene-by-gene (G×G) interactions. To identify G×E and G×G, we screened markers for patterns indicative of interactions (relationship loci [rQTL] and variance heterogeneity loci [vQTL]). rQTL exist when the correlation between multiple traits varies by genotype and vQTL occur when the variance of a trait

A Review of Cooking of Potatoes (Solanum tuberosum L.) Served in Large-Scale Food-Service Systems, Including Industrial Pre-Treatments

Potatoes (Solanum tuberosum L.) often constitute a meal’s main carbohydrate source. When consumed outside the home, dishes are often prepared in large-scale food service systems, like school canteens and hospitals. To manage the logistics of serving the required quantities of potatoes, raw tubers must be prepared by washing, industrial peeling, preservative actions, and packaging to stand transpor

Novel risk factors associated with common vaginal infections : a nationwide primary health care cohort study: Novel risk factors for vaginal infections

Objective: This study aimed to estimate the association between potential risk factors and common vaginal infections using nationwide primary health care and other national registers. Methods: An open cohort study consisting of 2,357,711 women aged 15 years to 50 years (2001 to 2018) was conducted in Sweden. The outcomes were first event of vulvovaginal candidiasis (VVC) and bacterial vaginosis (B

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In this work, the fluorescence of FLEET (femtosecond laser electron excited tagging) was enhanced by two color femtosecond laser. the intensity of FLEET was increased about 20% with two laser pulses that were 400 μJ/pulse at 266 nm and 3 mJ/pulse at 800 nm, and the results indicated that there was nearly no influence on lifetime and wavelength of fluorescence from FLEET. This result provides many

Casks from Gribshunden (1495) – Dendrochronology of Late Medieval Shipboard Victual Containers

Wooden casks were used extensively to transport goods in medieval Europe but have beenlargely overlooked in Scandinavian marine archaeological studies. We present a study ofcasks recovered from the Danish-Norwegian royal flagship Gribshunden, which sank inthe summer of 1495 outside Stora Ekö Island in southeastern Sweden. Duringexcavations in 2020–2021, archaeologists recovered 135 wooden staves a