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Impact of allograft ischemic time on long-term survival in lung transplantation : a Swedish monocentric study

Purpose: The influence of allograft ischemic time (IT) on short- and long-term mortality remains under debate in lung transplantation (LTx). Due to a scarcity in donors, better understanding of IT might improve the outcome after LTx. Methods: Between January 1990 and June 2016; 307 patients underwent LTx at Lund university hospital, Sweden. The end-point used was death/Re-LTx assessed by Cox regre

Association of Established Blood Pressure Loci With 10-Year Change in Blood Pressure and Their Ability to Predict Incident Hypertension

Background Genome-wide association studies have identified >1000 genetic variants cross-sectionally associated with blood pressure variation and prevalent hypertension. These discoveries might aid the early identification of subpopulations at risk of developing hypertension or provide targets for drug development, amongst other applications. The aim of the present study was to analyze the associat

Use of cardiovascular drugs and risk of incident heart failure in patients with atrial fibrillation

Congestive heart failure (CHF) is the most important cause of death in patients with atrial fibrillation (AF). We aimed to study the association between cardiovascular drugs in AF patients and incident CHF. The study population included all adults (n = 120 756) aged ≥45 years diagnosed with AF in Sweden diagnosed for the period 1998-2006. Outcome was incident congestive heart failure (follow-up 20

Direct and indirect selection on mate choice during pollen competition : Effects of male and female sexual traits on offspring performance following two-donor crosses

Mate choice in plants is poorly understood, in particular its indirect genetic benefits, but also the direct benefits of avoiding harmful matings. In the herb Collinsia heterophylla, delayed stigma receptivity has been suggested to enhance pollen competition, potentially functioning as a female mate choice trait. Previous studies show that this trait can mitigate the cost of early fertilization ca

Influence of Psychosocial Variables on the Health of People Living in Housing Exclusion

The aim of this study was to analyze the influence of some personal characteristics, health variables, and social support on the self-rated health of people in housing exclusion in Spain. For that purpose, we used the FOESSA Survey of Social Integration and Needs database, with a final sample of 1574 households. Being more educated and reporting a good life satisfaction stood out as the main facto

Estimated salt intake and risk of atrial fibrillation in a prospective community-based cohort

Introduction: Hypertension predisposes to atrial fibrillation (AF) – a major risk factor for ischaemic stroke. Since a high dietary salt consumption is associated with hypertension, we investigated the association between urinary sodium excretion as a marker for dietary sodium intake and risk of new-onset AF in community-dwelling adults. Method: The UK Biobank includes 40- to 69-year-old British r

Att göra många till en – om populismens logik

Den här artikeln introducerar Ernesto Laclaus teori om populism för den skan-dinaviska retorikforskningen i syfte att adressera en befintlig brist på begrepps liga resurser för att analysera populistiska artikulationer. Laclaus teori om populism syftar till att förklara de retoriska processer inneboende i varje politisk kamp såväl som att förstå konfliktdimensionen som konstitutiv för demokratisk po

Survival in 31 670 patients with thin melanomas : a Swedish population-based study

BACKGROUND: The incidence of cutaneous malignant melanoma (CMM) continues to increase in most countries worldwide and the majority are diagnosed with thin tumours (≤ 1 mm).OBJECTIVES: The aim of the present study was to investigate the melanoma-specific survival (MSS) as well as conditional MSS (CMSS) in patients with thin CMM in Sweden.PATIENTS AND METHODS: Clinical and histological parameters we

A novel non-antimicrobial treatment of bacterial vaginosis : An open label two-private centre study

Background: Bacterial vaginosis (BV) is the most common cause of vaginal discharge. It is caused by an imbalance in the normal vaginal microbiota. Symptoms include an offensive odour. Standard oral or vaginal antimicrobial treatments have high immediate cure rates but almost as high recurrence rates. pHyph, a vaginal pessary, contains glucono-delta-lactone (GDL) and sodium gluconate (NaG) which re

High-Sensitivity Assessment of Phagocytosis by Persistent Association-Based Normalization

Phagocytosis is measured as a functional outcome in many research fields, but accurate quantification can be challenging, with no robust method available for cross-laboratory reproducibility. In this study, we identified a simple, measurable parameter, persistent prey-phagocyte association, to use for normalization and dose-response analysis. We apply this in a straightforward analytical method, p

Localisation of logistics preparedness in international humanitarian organisations

Purpose: To meet the rising global needs, the humanitarian community has signed off on making a strategic change toward more localisation, which commonly refers to the empowerment of national and local actors in humanitarian assistance. However, to this date, actual initiatives for localisation are rare. To enhance understanding of the phenomenon, the authors explore localisation of logistics prep

C-reactive protein as a prognostic factor in intensive care admissions for sepsis : A Swedish multicenter study

Purpose: C-reactive protein (CRP) is not included in the major intensive care unit (ICU) prognostic tools such as the Simplified Acute Physiology Score (SAPS). We assessed CRP on ICU admission as a SAPS-3 independent risk marker for short-term mortality and length of stay (LOS) in ICU patients with sepsis. Materials and methods: Adult ICU admissions satisfying the Sepsis-3 criteria to four souther

Electron-ion coincidence spectroscopy of a large organic molecule : photofragmentation of avobenzone after valence and core ionisation

The Avobenzone (AVOB) molecule is very photoactive and undergoes irreversible degradation upon irradiation. We studied its valence and core-level (C1s and O1s) photoionisation and subsequent photofragmentation with photoelectron spectroscopy and photoelectron-photoion-photoion coincidence (PEPIPICO) spectroscopy. AVOB is one of the largest molecules studied with this technique. The results show th

Living with the memories—parents’ experiences of their newborn child undergoing heart surgery abroad : A qualitative study

Parents of children with a congenital heart defect needing complex heart surgery are at high risk of developing health problems. One can assume that parents whose child undergoes heart surgery abroad will undoubtably face added and unique stressors and health vulnerabilities. The aim of this qualitative study was to explore the transition experiences of parents of children who underwent a complex

Fluorine in the solar neighbourhood : Modelling the Galactic thick and thin discs

We investigate the evolution of the abundance of fluorine in the Milky Way thick and thin discs by means of detailed chemical evolution models compared with recent observational data. The chemical evolution models adopted here have already been shown to fit the observed abundance patterns of CNO and α-elements as well as the metallicity distribution functions for the Galactic thick and thin disc s