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Background: Children whose parents have alcohol use problems are at an increased risk of several negative consequences, such as poor school performance, an earlier onset of substance use, and poor mental health. Many would benefit from support programs, but the figures reveal that only a small proportion is reached by existing support. Digital interventions can provide readily accessible support a

Ammonium nitrate in aqueous solution was investigated with synchrotron radiation based photoelectron spectroscopy using two types of liquid jet nozzles. Electron emission from a cylindrical microjet of aqueous ammonium nitrate solution was measured at two different angles relative to the horizontal polarization of the incident synchrotron radiation, 90° and 54.7° (the “magic angle”), for a range o

Intolerance of uncertainty (IU) is the tendency to react negatively on affective, cognitive and behavioural levels to uncertain situations and to harbour negative beliefs about the implications of uncertainty. IU has been linked to psychopathology and shown to impact treatment outcomes. This study systematically reviewed the literature and performed a meta-analysis of the effects of psychotherapy

Background/Aim: Anterior resection is the gold standard surgery for high and middle rectal tumors. In cases where anterior resection is not feasible, the surgeon resorts to a non-restorative approach such as Hartmann’s procedure or abdominoperineal resection. It is not well studied how Hartmann’s procedure impacts quality of life. This cross-sectional cohort study compares the long-term quality of

Histidine is a key amino-acid residue in proteins with unique properties engendered by its imidazole side chain that can exist in three different states: two different neutral tautomeric forms and a protonated, positively charged one with a pKa value close to physiological pH. Commonly, two or all three states coexist and interchange rapidly, enabling histidine to act as both donor and acceptor of

Sociodemographic inequalities in student achievement are a persistent concern for education systems and are increasingly recognized to be intersectional. Intersectionality considers the multidimensional nature of disadvantage, appreciating the interlocking social determinants which shape individual experience. Intersectional multilevel analysis of individual heterogeneity and discriminatory accura

e consider waveform iterations for dynamic coupled problems with respect to therole of time window length. We review existing theoretical results about the error of waveformiterations and the role of the time window length. Furthermore, we present numerical resultsfor waveform iterations with both time adaptive sub solvers and with fixed time steps. Thisway, we are able to give a recommendation on

Secondary lymphedema (LE) following breast cancer-related surgery is a life-long complication, which currently has no cure. LE induces significant regional adipose tissue deposition, requiring liposuction as a treatment. Here, we aimed to elucidate the transcriptional, metabolomic, and lipidomic signature of the adipose tissue developed due to the surgery-induced LE in short- and long-term LE pati

The double nucleation mechanism of amyloid β (Aβ) peptide aggregation is retained from buffer to cerebrospinal fluid (CSF) but with reduced rate of all microscopic processes. Here, we used a bottom-up approach to identify retarding factors in CSF. We investigated the Aβ42 fibril formation as a function of time in the absence and presence of apolipoprotein A-I (ApoA-I), recombinant high-density lip

Humanitarian logistics (HL) is a relatively new research area that requires clear boundaries and a defined foundational perspective. Recent disasters have shown that the scope of HL is expanding, as in cases of cash-based interventions, outsourcing to commercial companies, and stronger involvement of local communities. These changes imply the importance of scrutinizing the old definitions of HL an

Glioblastoma, a type of cancer affecting the central nervous system, is characterized by its poor prognosis and the dynamic alteration of its metabolic phenotype to fuel development and progression. Critical to cellular metabolism, mitochondria play a pivotal role, where the acetylation of lysine residues on mitochondrial enzymes emerges as a crucial regulatory mechanism of protein function. This

Introduction: Occupational balance and satisfaction with daily occupations are two central concepts in occupational science. The aim of the present study was therefore to explore associations between different aspects of occupational balance and satisfaction with daily occupations. A second aim was to explore whether different aspects of occupational balance predicted satisfaction with daily occup

Metal halide perovskites attract significant interest due to their remarkable performance in optoelectronic devices. However, the gap in understanding the relationship between their nanoscale structure and properties limits their application towards novel devices. In this work, twinned ferroelastic domains in single 500 nm CsPbBr3 particles are studied with 3D Bragg coherent x-ray diffraction imag

Background: The incidence of detected ductal carcinoma in situ (DCIS) continues to increase and now accounts for 14% of all breast cancer, and 20%–25% of screen-detected cases. Treatment trends of DCIS are important in order to inform the ongoing debate about possible overdiagnosis and overtreatment, but have not been investigated for over a decade in Australia and New Zealand. Against this backgr

The present research examines the hypothesis that political leftists and rightists mentally construe collective threats differently, such that each political side views the threats that are meaningful to them as close and concrete, whereas other threats are underemphasized and perceived as distant and abstract. In two studies (total N = 796) we show that Israeli-Jewish political leftists perceive

We propose a new model that estimates the long- and short-run components of the variances and covariances. The advantage of our model to the existing DCC-based models is that it uses the same form for both the variances and covariances and estimates these moments simultaneously. We apply this model to obtain long- and short-run factor betas for industry test portfolios. We find that the risk premi

Preceding studies on morbidities and mortalities associated with TB in a cohort of HIV care indicate high incidence of TB development and premature death among patients on highly active antiretroviral treatment (HAART). This study aims to measure the rate of TB, TB mortality, and associated risk factors following commencement of HAART in a cohort of patients attending HIV care in Ethiopia. Patient

In this work, a thermodynamically consistent constitutive framework is introduced that is capable of reproducing the significant time-dependent behaviour of austenite-to-bainite phase transformations. In particular, the aim is to incorporate the effect of these diffusion-controlled processes by plasticity-like evolution equations instead of incorporating related global diffusion equations. To this