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We optimize traffic signal timing sequences for a section of a traffic net-work in order to reduce congestion based on anticipated demand. The system relieson the accuracy of the predicted traffic demand in time and space which is carriedout by a neural network. Specifically, we design, train, and evaluate three differentneural network models and assert their capability to describe demand from tra

Drugs that antagonize D2-like receptors are effective antipsychotics, but the debilitating movement disorder side effects associated with these drugs cannot be dissociated from dopamine receptor blockade. The "atypical" antipsychotics have a lower propensity to cause extrapyramidal symptoms (EPS), but the molecular basis for this is not fully understood nor is the impact of inverse agonism upon th

Sex chromosomes have evolved repeatedly across the tree of life and often exhibit extreme size dimorphism due to genetic degeneration of the sex-limited chromosome (e.g. the W chromosome of some birds and Y chromosome of mammals). However, in some lineages, ancient sex-limited chromosomes have escaped degeneration. Here, we study the evolutionary maintenance of sex chromosomes in the ostrich (Stru

Lignin degrading system of white rot fungi and its exploitation in the decolorization of synthetic dyes has been used in a wide array for human benefits. In this study, decolorization of two model synthetic dyes, Reactive Black 5 (RB5) and Methylene Blue (MB) with the ability of Kraft lignin degradation were investigated using new fungal isolates from Malaysian soils. The most potent isolates WICC

Misophonia is an often chronic condition characterized by strong, unpleasant emotional reactions when exposed to specific auditory or visual triggers. While not currently defined within existing classification systems, and not clearly fitting within the framework of extant psychiatric conditions, misophonia has historically been studied most frequently within the context of obsessive-compulsive an

Semiconductor quantum dot (QD) sensitization is one of the most attractive structures to employ QDs for photovoltaic application. The function of QD sensitized solar cells (QDSSC) is controlled by the interfacial charge transfer dynamics. Here we employ transient absorption spectroscopy (TAS) to assess charge transfer dynamics at CdS QD/TiO2 interface, and correlate their dynamics with their solar

A critical aspect in strategic modeling of transportation systems is user heterogeneity. In many real-world scenarios, e.g., when tolls are charged and drivers have different trade-offs between time and money, or when they get informed about current congestion by different routing apps, modeling users as rational decision makers with homogeneous utility functions becomes too restrictive. While glo

Mating system shifts from outcrossing to selfing are frequent in plant evolution. Relative to outcrossing, selfing is associated with reduced parental conflict over seed provisioning, which may result in postzygotic, asymmetric, reproductive isolation in crosses between populations of different mating systems. To test the hypothesis that post-pollination reproductive isolation between populations

Background: Postoperative pain is common but often difficult to assess, and there are many potential confounders. Over the last decades, the gender of investigator as well as participant has been found to influence pain perception in both preclinical and clinical studies. However, to our knowledge this has not been studied in various postoperative patients. Objectives of this study were to test th

This research aims to shed light on the formulation of returns management strategies and to identify key returns management components in developing more effective returns management strategies. Anchored in supply chain orientation and supply chain alignment research, we use a multiple confirmatory case study of six retailers operating in online commerce. Interviews with fifteen managers provided

A novel macro intermediate based on poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) (PHBHHx) was synthesized for use in the copolymerization with dimethyl amino ethyl methacrylate (DMAEMA). Methyl amino ethanol was reacted with PHBHHx to prepare a dihydroxy terminated polyester. The hydroxyl ends of the obtained PHBHHx derivatives were capped with 4,4’-azobis cyanopentanoic acid to obtain the PHBHHx

Construction and demolition workers are exposed to high levels of particulate matter (PM) from building materials throughout their working life. Although nano-enabled building materials (NEBMs) may improve the performance and functionality of buildings, concerns are being raised regarding health risks from occupational exposure to PM from NEBMs. In this work, an experimental set-up for integrated

Objectives: In India, cervical cancer is the most common cancer among women and makes up for up to 29% of all registered cancer in females. Cancer-related pain is one of the major distressing symptoms for all cancer patients. Pain is characterised as somatic or neuropathic, and the total pain experience is often mixed. Conventional opioids are the backbone of analgesic treatment but are most often

This paper examines how social media can support communities of patients with chronic illness and their care givers. This study is a qualitative case study and is informed by grounded theory. Sociomateriality is adopted as a theoretical lens to understand and explain the key findings. Our findings suggest that there is a dynamic relation between the contrary roles that social media in chronic care

The failure of the EU and its Member States to adequately respond to increased refugee movements since 2015, has caused disagreement on how the principle of solidarity and fair sharing of responsibility should be given effect in the context of a reformed European policy on migration. In September 2020, theEuropean Commission proposed the new Pact on Migration and Asylum which was meant to promote

BACKGROUND: An investigation of trends of incidence and net survival (NS) for endometrial cancer in Sweden.METHODS: Morphologically verified endometrial carcinoma diagnosed 1960 to 2014 were collected from the nation-wide Swedish Cancer Registry. Endometrial cancer patients were assessed with regards to time trends for incidence and 54,825 cases remained for survival analyses. Cases diagnosed 1995

Background: Despite advance in care of people with an ostomy, related complications remain prevalent. The objective of this study was to examine short- and long-term healthcare resource utilization and associated costs after ostomy creation. Methods: This observational study was based on retrospectively collected data from national and regional Swedish registries. The population consisted of peopl

The assignment of products to storage locations significantly impacts the efficiency of warehouse operations. We propose a multi-phase optimizer for a Storage Location Assignment Problem (SLAP) where solution quality is based on a distance estimate of future-forecasted order picking. Candidate assignments are first sampled using a Markov Chain accept/reject method. Future-forecasted pick-rounds ar