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Splicing and polyadenylation of human papillomavirus type 16 mRNAs

The human papillomavirus type 16 (HPV16) life cycle can be divided into an early stage in which the HPV16 genomic DNA is replicated, and a late stage in which the HPV16 structural proteins are synthesized and virions are produced. A strong coupling between the viral life cycle and the differentiation state of the infected cell is highly characteristic of all HPVs. The switch from the HPV16 early g

Physical inactivity during leisure time and irregular meals are associated with functional gastrointestinal complaints in middle-aged and elder subjects

Objectives: Few studies have examined how lifestyle factors affect functional gastrointestinal disorders. The aim of this study was to see if leisure time physical inactivity, dietary habits or body mass index (BMI) were associated with increased risk of functional abdominal pain, functional bloating, functional constipation or functional diarrhea. Methods and materials: This study was based on a

Kinetic influence of siliceous reactions on structure formation of mesoporous silica formed via the co-structure directing agent route

We investigate the mechanism responsible for the formation of mesoporous silica formed with the so-called costructure directing agent (CSDA) route. The synthesis relies on the interaction between silica source (tetraethylorthosilicate), cationic surfactant (C18H37N+(CH3)2(CH2)3N+(CH3)3Br2), and CSDA (carboxyethylsilanetriol), which results in a material functionalized with carboxylic groups. Depen

Fabrication of Nickel-YSZ cermet nanofibers via electrospinning

Abstract The Ni-YSZ cerment as a promising anode for solid oxide fuel cells and its performance strongly depends on its miscrocture. This work focused on fabrication of Ni-8YSZ nanofibers via an electrospinning technique using yttria and zirconia nanoparticles as precussors. The effects of viscosity on the quality of fibers were assessed by adjusting the polymer and solid contents in slurry. The f

A 280 W LDMOS broadband Doherty PA with 52% of fractional bandwidth based on a multi-line impedance inverter for DVB-T applications

We introduce a new technique for the design of an output combiner for Doherty power amplifier (DPA) and its effective exploitation for the development of a wideband laterally diffused metal oxide semiconductor (LDMOS) DPA. The design is enabled by a two-line impedance inverter for the DPA back-off operation, which is capable of 52% of fractional bandwidth. The technique is validated by the develop

Genetics of type 2 diabetes : It matters from which parent we inherit the risk

Type 2 diabetes (T2D) results from a co-occurrence of genes and environmental factors. There are more than 120 genetic loci suggested to be associated with T2D, or with glucose and insulin levels in European and multi-ethnic populations. Risk of T2D is higher in the offspring if the mother rather than the father has T2D. Genetically, this can be associated with a unique parent-of-origin (PoO) tran

Occupational stress among Swedish audiologists in clinical practice : Reasons for being stressed

Objective: The present study reports on the application of a Swedish translation of the audiologist occupational stress questionnaire (AOSQ) on audiologists working in Sweden. The relations between AOSQ scores and perceived effort, perceived rewards, coping strategies at work, demographic variables such as salary, education length, practise length, and practice type were tested. Design: A cross-se

An appropriate inspiratory flow pattern can enhance CO2 exchange, facilitating protective ventilation of healthy lungs

Background In acute lung injury, CO2 exchange is enhanced by prolonging the volume-weighted mean time for fresh gas to mix with resident alveolar gas, denoted mean distribution time (MDT), and by increasing the flow rate immediately before inspiratory flow interruption, end-inspiratory flow (EIF). The objective was to study these effects in human subjects without lung disease and to analyse the re

Catalytic C-H oxidations by nonheme mononuclear Fe(II) complexes of two pentadentate ligands: Evidence for an Fe(IV) oxo intermediate

The oxidation reactions of alkanes with hydrogen peroxide and peracids (peracetic acid (PAA) and m-chloroperoxybenzoic acid (mCPBA)) catalysed by two Fe(II) complexes of pentadentate {N5}-donor ligands have been investigated. Kinetic isotope effect experiments and the use of other mechanistic probes have also been performed. While the total yields of oxidized products are similar regardless of oxi

The Olson method for detection of acute myocardial ischemia in patients with coronary occlusion

An automated ECG-based method may provide diagnostic support in the management of patients with acute coronary syndrome. The Olson method has previously proved to accurately identify the culprit artery in patients with acute coronary occlusion. Methods The Olson method was applied to 360 patients without acute myocardial ischemia and 52 patients with acute coronary occlusion. Results This study es

Information and/or medical technology staff experience with regulations for medical information systems and medical devices

Objectives Regulations heavily control medical technology (MT), which often includes information technology (IT), but staff experiences related to these regulations are unknown. The study aim was to assess Swedish IT/MT staff experiences regarding regulations for medical devices and medical information systems. Methods An anonymous, ten-item, self-report questionnaire was administered to IT and MT

Framework for research on improved life quality

The Sound Environment Center at Lund University has for over ten years hosted interdisciplinary research on sound environment issues promoting an exchange of ideas between researchers through research projects, interdisciplinary symposiums and publications. The center aims at developing a holistic view to a field that is scientifically fragmented. Ranging from acoustics, noise abatement and sounds

Explosive ice multiplication by mechanical break-up in ice-ice collisions : A dynamical system-based study

Mechanical break-up in ice-ice collisions observed in the laboratory can lead to explosive ice multiplication. The possibility is examined in detail by constructing an idealized analytical single-point (zero-dimension) model assuming spatial homogeneity within a cloud. The rate of generation of primary ice is fixed at a constant value over time, corresponding to a situation in which the relative h

Programme characteristics and everyday occupations in day centres and clubhouses in Sweden

Background: Meaningful everyday occupations are important for mental health and recovery and are provided by both community-based day centres (DCs) and clubhouses. It is unknown, however, if any of the two has more recovery-promoting features. Objective: This nine-month longitudinal study compared DC and clubhouses, concerning the users’ perceptions of unit and programme characteristics, and aspec

Ischemic Stroke and Six Genetic Variants in CRP, EPHX2, FGA, and NOTCH3 Genes : A Meta-Analysis

Background: Ischemic stroke (IS) is a leading cause of death and disability worldwide. As genetic heritability for IS is estimated at about 35%-40%, the identification of genetic variants associated with IS risk is of great importance. The main objective of this study was to carry out a meta-analysis for polymorphisms in CRP, EPHX2, FGA, and NOTCH3 genes and the risk for IS. Methods: Literature se