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Please cite this paper as: Källén B, Olausson P. Vaccination against H1N1 influenza with Pandemrix(®) during pregnancy and delivery outcome: a Swedish register study. BJOG 2012; DOI: 10.1111/j.1471-0528.2012.03470.x. Objective To describe a large study on pregnancy outcome after vaccination against H1N1 during the 2009/10 pandemic. Design A cohort study of women vaccinated with Pandemrix(®) during

Popular Abstract in Swedish Personer som drabbas av hjärtstopp riskerar grava hjärnskador p.g.a. brist på blodflöde till hjärnan. Patienterna blir ofta långvarigt medvetslösa och vårdas på intensiv¬vårdsavdelning i respirator. Risken för hjärnskada kan minskas med kyl¬behandling. Under kylbehandlingen, cirka 1.5 dygn, får patienten sederande och ev. muskelavslappnande medicin för att minska ”huttrAbstract Therapeutic hypothermia (TH) is the only treatment available to reduce neurological sequels for unconscious patients following cardiac arrest (CA). TH requires sedation and muscular relaxation, obscuring the clinical neurological examination for estimation of prognosis, and clinical decision making. Continuous amplitude-integrated EEG (aEEG) has been used to predict outcome in neonates

The pro-inflammatory mediator LTD4 is an important component in the pathogenesis of inflammatory conditions as inflammatory bowel diseases. Patients suffering from inflammatory bowel diseases face an increased risk of intestinal cancer development. Therefore it is important to investigate the role of LTD4 signalling in cancer development and progression. In this thesis I show that there is an end

Conventional surveillance systems are omnipresent and most are still based on analog techniques. Migrating to the digital domain grants access to the world of digital image processing enabling automation of such systems, which means extracting information from the image stream without human interaction. The resolution, frame rates, and functionality in these systems are continuously increasing alo

The Swedish teaching profession, Nazism and Soviet Communism from 1933 to 1945 The “Democratic School” was a concept that Swedish teachers used regularly to describe the school that they had participated in building up. In the interwarperiod, the Democratic School was confronted with two major challenges, i.e. German Nazism and Soviet Communism. This thesis has, in a comparative form, investigate

Purpose of this paper The purpose of this paper is to propose a framework for describing and analyzing misalignments in supply chain management related to changes in supply chain structures, processes, and management components. Design/methodology/approach Based on the systems approach, a single-case study including several embedded cases from the same supply chain was deployed. This was done acc

Binary chloromethane-argon clusters were investigated by means of synchrotron-radiation-based valence and core level photoelectron spectroscopies. The host argon clusters were produced by adiabatic expansion and exposed to chloromethane molecules using the pick-up technique. The study of the valence spectrum showed that heterogeneous clusters were formed. The spatial distribution of chloromethane

The aim of this study was to assess whether a school-based program with expanded physical education lessons was effective in increasing children's physical capacity and in preventing excessive weight gain in children. The study performed in 2000-2003 comprised 132 children, 73 boys and 59 girls at baseline 6-9 years and in follow-up 9-12 years, attending two different schools with a similar size,

The opportunistic human pathogen Pseudomonas aeruginosa causes a wide range of diseases. To cross host innate immune barriers, P. aeruginosa has developed efficient strategies to escape host complement attack. In this study, we identify the 57-kDa dihydrolipoamide dehydrogenase (Lpd) as a surface-exposed protein of P. aeruginosa that binds the four human plasma proteins, Factor H, Factor H-like pr

Organometallic complexes containing terminal metal nitrides and phosphides are important synthetic reagents. Laser-ablated group 6 metal atoms react with NF3, PF3, and PCl3 to form the simple lowest energy N MF3, and P MX3 products following insertion and halogen transfer, with the exception of P CrF3, which is a higher energy species and is not observed. The E MX3 pnictide metal trihalide molecul

Background: Resource allocation in public health care principally involves politicians, administrators, and physicians. They all have their different roles, agendas and ambitions when it comes to how public health care resources should be spent. Previous studies on attitudes among health-care stakeholders have mainly focused on views and preferences among clinical decision-makers, while less atten

Although cancer is a heterogeneous disease, a common theme in tumor cells is the deregulation of cell division, which renders tumor progression independent of otherwise necessary internal or external growth cues. This may provide cancer cells with the ability to divide indefinitely, posing a threat to the rest of the organism. As the tumor grows, nearby healthy tissues are harmed, which eventually

Purpose – The purpose of this paper is to systematically and critically review the extant literature on the design of global production and distribution networks to identify gaps in the literature and identify future research opportunities. The design aspects deal with strategic and structural decisions such as: opening or closing of manufacturing plants or distribution centres, selection of locat

OBJECTIVE: To assess the outcome of vacuum-assisted wound closure (VAC(®)) therapy for infected bypass grafts. METHODS: A retrospective 7-year review of patient records from 2004 to 2011 of all patients receiving VAC(®) therapy for infected bypass grafts. RESULTS: Thirty-seven patients with 42 wounds and 45 infected bypass (28 synthetic) grafts received VAC(®) treatment. Two serious bleeding e

The tyrosine kinase encoding genes ABL1 and FGFR1 are involved in fusion genes underlying the myeloproliferative neoplasms chronic myeloid leukemia (CML) and the 8p11-myeloproliferative syndrome (EMS). CML and EMS are both myeloproliferative disorders with an initiating, relatively indolent, chronic phase that after some time progresses into acute myeloid or lymphoid leukemia. The mechanisms under

This study aims to assess the effect of radiation treatment on the tumour vasculature and its downstream effects on hypoxia and choline metabolism using a multimodal approach in the murine prostate tumour model CWR22. Functional parameters derived from Positron Emission Tomography (PET)/Computer Tomography (CT) with (18)F-Fluoromisonidazole ((18)F-FMISO) and (18)F-Fluorocholine ((18)F-FCH) as well

The present thesis concerns the involvement of EWSR1 and FUS fusion genes, and the chimeric proteins they encode, in tumorigenesis. In Article I, the EWSR1 promoter, which regulates the expression of EWSR1 fusion genes, was characterized and regions that were crucial for promoter activity could be identified. The sequence was found to have bidirectional activity and is likely to regulate also RHBD

Objective. Collagenous colitis (CC) and lymphocytic colitis (LC) are two subtypes of microscopic colitis (MC). Even though they most often are described as different entities they share many clinical and histological features. The aim of this study was to investigate the occurrence of conversion between CC and LC in a larger cohort of patients. Materials and methods. All 664 patients in our Pathol