Filetype
Bats navigate the dark using echolocation. Echolocation is enhanced by external ears, but external ears increase the projected frontal area and reduce the streamlining of the animal. External ears are thus expected to compromise flight efficiency, but research suggests that very large ears may mitigate the cost by producing aerodynamic lift. Here we compare quantitative aerodynamic measures of fli
Cerebrovascular disease (CVD) remains a leading cause of death and the leading cause of adult disability in most developed countries. This work summarizes state-of-the-art, and possible future, diagnostic and evaluation approaches in multiple stages of CVD, including (i) visualization of sub-clinical disease processes, (ii) acute stroke theranostics, and (iii) characterization of post-stroke recov
Background-Treatment with renin-angiotensin system (RAS) inhibitors might restrain the structural/electrical remodeling associated with atrial fibrillation (AF). Limited evidence exists regarding the potential benefits of RAS inhibition post-acute myocardial infarction (AMI) in patients with AF. This study sought to assess the association between RAS inhibition and all-cause mortality and new-onse
One of the many unresolved questions regarding the permeability of the glomerular filtration barrier is the reason behind the marked difference in permeability between albumin and polysaccharide probe molecules such as Ficoll and dextran of the same molecular size. Although the differences in permeability have been mainly attributed to charge effects, we have previously shown that this would requi
BACKGROUND: Sense of Coherence (SOC) is important for successful adaptation and mental well-being in people with life-long medical conditions. Late effects of polio (LEoP) often lead to a life-long disability, but no study has assessed SOC in this population. OBJECTIVE: To assess SOC in persons with LEoP and to explore the association between SOC, demographics (age, gender, marital status and leve
AIMS: Cardiovascular disease (CVD) is one of the leading causes of mortality and morbidity worldwide, including in Sweden. The main aim of this study was to explore the temporal trends and spatial patterns of CVD in Sweden using spatial autocorrelation analyses.METHODS: The CVD admission rates between 2000 and 2010 throughout Sweden were entered as the input disease data for the analytic processes
It is estimated that the number of devices connected to the Internet will be 50 billion by 2020. How should a not-so-tech-savvy end user be able to discover and directly interact with a myriad of connected things in an intuitive and comfortable manner? Up until now, smartphones have shown potential for managing the Internet of Things (IoT) environments, but we cannot rely on that technology. Weara
Urological problems can be caused by diseases that affect the bladder wall and its innervation. Contraction and relaxation of smooth muscle cells (SMCs) is essential for maintaining detrusor function and for emptying the bladder. It is well established that a family of regulatory proteins called Myocardin Related Transcription Factors (MRTFs) controls the property of SMCs. SMCs have a number of un
In most industrialized countries, there are substantial gender differences in field of study, resulting in gender segregated labor markets. The present research (N = 457, M age = 14.98) investigated a diverse range of predictors of Swedish adolescents’ choice of preparatory (STEM; humanistic) and terminal (e.g., electrician; health care) programs. The results revealed that social identity related
Due to the overpopulation in the main cities and shortage of water in Egypt, finding new possible reclamation areas becomes an urgent necessity. The area northwest of El Sadat city can be considered one of the most promising new reclamation areas. This study focuses on detecting the groundwater aquifers, delineating the best localities to drill groundwater boreholes, and evaluation of the groundwa
Purpose: Most patients recover well from a distal radius fracture (DRF). However, approximately one-fifth have severe disability after 1 year when evaluated using the Disabilities of the Arm, Shoulder, and Hand (DASH) questionnaire. In the present study, we evaluated this subgroup of patients in our register with an inferior outcome. We hypothesized that the patient-reported outcome would improve
Exposure to inorganic arsenic (As), a carcinogen and epigenetic toxicant, has been associated with lower circulating levels of insulin-like growth factor 1 (IGF1) and impaired growth in children of pre-school age. The aim of this study was to assess the potential impact of exposure to As on IGF1 and insulin-like growth factor-binding protein 3 (IGFBP3) as well as DNA methylation changes in 9-year-
GPR30, or G protein-coupled estrogen receptor (GPER), is a G protein-coupled receptor (GPCR) that is currently attracting considerable attention in breast cancer and cardiometabolic regulation. The receptor was reported to be a novel membrane estrogen receptor mediating rapid non-genomic responses. However, questions remain about both the cognate ligand and the subcellular localization of receptor
Formation of partially constrained precipitates such as hydride blisters and oxide nodules have been reported on surfaces of Zr-alloy components of pressurised heavy water reactors and is associated with a large increase in volume. Such a change in volume imposes large stresses in the material surrounding the precipitate and may facilitate stable crack growth through delayed hydride cracking. In t
The fifth generation wireless system (5G) is expected to handle with an unpredictable number of heterogeneous connected devices while guaranteeing a high level of security. This paper advances a groupbased Authentication and Key Agreement (AKA) protocol that contributes to reduce latency and bandwidth consumption, and scales up to a very large number of devices. A central feature of the proposed p
Typhoon Haiyan damaged around a million houses in the Philippines in November 2013. It especially affected the poor. Using a realist laminated ontology, this paper explains how multiple causal mechanisms triggered unexpected outcomes in the housing recovery programme in the province of Leyte. The proposed causal mechanisms were: the intentional causal agency of the Filipino power elite; the collab
Sex differences in selection are ubiquitous in sexually reproducing organisms. When the genetic basis of traits is shared between the sexes, such sexually antagonistic selection (SAS) creates a potential constraint on adaptive evolution. Theory and laboratory experiments suggest that environmental variation and the degree of local adaptation may all affect the frequency and intensity of SAS. Here,
