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Experiences of SENSory Relearning of the UPPer Limb (SENSUPP) after Stroke and Perceived Effects : A Qualitative Study

Recently, it was shown that sensory relearning of the upper limb (SENSUPP) is a promising intervention to improve sensorimotor function after stroke. There is limited knowledge, however, of how participants perceive the training. Here, we explored how persons with sensory impairments in the upper limb experienced the SENSUPP protocol (combined sensory-and motor training and home exercises for 5 we

Estimating slope from raster data : A test of eight different algorithms in flat, undulating and steep terrain

Eight frequently used slope algorithms based on a DEM (Digital Elevation Model) have been compared in flat, gently sloping/undulating, and steep terrain in order to investigate differences in estimated results. The matter of scale/resolution has not been considered, and the focus has not been on comparing the estimates with "ground truth" data but on comparisons between the different algorithms. P

Ultrafast Dynamic Contrast-enhanced MRI of the Breast : How Is It Used?

Ultrafast dynamic contrast-enhanced (UF-DCE) MRI is a new approach to capture kinetic information in the very early post-contrast period with high temporal resolution while keeping reasonable spatial resolution. The detailed timing and shape of the upslope in the time-intensity curve are analyzed. New kinetic parameters obtained from UF-DCE MRI are useful in differentiating malignant from benign l

Dual action of the cannabinoid receptor 1 ligand arachidonyl-2′-chloroethylamide on calcitonin gene-related peptide release

Background: Based on the current understanding of the role of neuropeptide signalling in migraine, we explored the therapeutic potential of a specific cannabinoid agonist. The aim of the present study was to examine the effect of the synthetic endocannabinoid (eCB) analogue, arachidonyl-2′-chloroethylamide (ACEA), on calcitonin gene-related peptide (CGRP) release in the dura and trigeminal ganglio

Perceptions and Attitudes about Eating with the Fingers-An Explorative Study among Older Adults with Motoric Eating Difficulties, Relatives and Professional Caregivers

Difficulties of managing cutlery, manipulating food on the plate and transporting food to the mouth may negatively influence the ability for self-provision and nutritional status among older adults with motoric eating difficulties. The purpose was to explore perceptions and attitudes about eating with the fingers among older adults with motoric eating difficulties, and relatives and professional c

A new imaging technology based on Compton X-ray scattering

A feasible implementation of a novel X-ray detector for highly energetic X-ray photons with a large solid angle coverage, optimal for the detection of Compton X-ray scattered photons, is described. The device consists of a 20 cm-thick sensitive volume filled with xenon at atmospheric pressure. When the Compton-scattered photons interact with the xenon, the released photoelectrons create clouds of

Genetic and phenotypic discordance in cardiometabolic diseases

Cardiometabolic conditions such as obesity and type 2 diabetes (T2D) are among the first causes of death globally, and the number of people affected is rapidly increasing. Both conditions are intricately connected and are associated with many life-threatening cardiovascular disease (CVD). However, both obesity and T2D are highly heterogeneous, such that not all individuals with these conditions de

Anastomotic Leakage in Relation to Type of Mesorectal Excision and Defunctioning Stoma Use in Anterior Resection for Rectal Cancer

BACKGROUND: Anastomotic leakage after anterior resection for rectal cancer is more common after total mesorectal excision compared to partial mesorectal excision but might be mitigated by a defunctioning stoma. OBJECTIVE: The aim is to assess how anastomotic leakage is affected by type of mesorectal excision and defunctioning stoma use. DESIGN: This is a retrospective multicenter cohort study eval

Feasibility-Usability Study of a Tablet App Adapted Specifically for Persons with Cognitive Impairment-SMART4MD (Support Monitoring and Reminder Technology for Mild Dementia)

Population ageing within Europe has major social and economic consequences. One of the most devastating conditions that predominantly affects older people is dementia. The SMART4MD (Support Monitoring and Reminder Technology for Mild Dementia) project aims to develop and test a health application specifically designed for people with mild dementia. The aim of this feasibility study was to evaluate

Major depressive episodes over the course of 7 years and hippocampal subfield volumes at 7 tesla MRI : the PREDICT-MR study

INTRODUCTION: Smaller hippocampal volumes have been associated with major depressive disorder (MDD). The hippocampus consists of several subfields that may be differentially related to MDD. We investigated the association of occurrence of major depressive episodes (MDEs), assessed five times over seven years, with hippocampal subfield and entorhinal cortex volumes at 7 tesla MRI.METHODS: In this p

The household financial burden of non-communicable diseases in low- and middle-income countries : a systematic review

Background: The chronic nature of noncommunicable diseases (NCD) and costs associated with long-term care can result in catastrophic health expenditure for the patient and their household pushing them deeper into poverty and entrenching inequality in society. As the full financial burden of NCDs is not known, the objective of this study was to explore existing evidence on the financial burden of N

LidarCLIP or : How i Learned to Talk to Point Clouds

Research connecting text and images has recently seen several breakthroughs, with models like CLIP, DALL•E 2, and Stable Diffusion. However, the connection between text and other visual modalities, such as lidar data, has received less attention, prohibited by the lack of text-lidar datasets. In this work, we propose LidarCLIP, a mapping from automotive point clouds to a pre-existing CLIP embeddin

Gender agreement in Italian compounds with capo-

Gender inflection for animated nouns in Italian presents challenges influenced by societal pressures and linguistic structure, especially in morphologically complex words like compounds. The study investigates gender inflection distribution in compounds with capo- compared to other nouns (i.e., occupations traditionally performed by women, by men, and the word capo in isolation), exploring the int

The impact of different fixatives on immunostaining of lung adenocarcinomas in pleural effusion cell blocks

BACKGROUND: Cell blocks (CBs) are widely used for biomarker analyses such as immunostaining. Although immunohistochemistry on formalin-fixed paraffin-embedded tissues is standardized, there are multiple preparation methods and fixatives for cytology. Our objective was to investigate the effect of different common fixatives on the immunoreactivity of pleural effusion CBs with metastatic lung adenoc

Professional voice use in health and nursing care – Time for reconsideration? A scoping review

Background: Communication is a key tool in the nursing profession. It is known that listeners are sensitive to the speaker's voice and interpret the speaker's intentions primarily from the non-verbal signal conveyed. Aim: To map and discuss the current state of knowledge and research evidence on professional voice use in health and nursing care. Design and Method: A scoping review adherent to the

Bleeding phenotype according to factor level in 825 children with nonsevere hemophilia : data from the PedNet cohort

Background: Information on bleeding phenotype in nonsevere hemophilia may be used to determine target factor levels for prophylaxis or gene therapy in severe hemophilia. Objectives: To assess the association between endogenous factor level and bleeding phenotype in children with nonsevere (factor [F]VIII/FIX activity 1%-25%) hemophilia A (HA) and B without prophylaxis. Methods: Data on annualized

Limiting diffusion coefficients of glufosinate ammonium, cymoxanil and imidacloprid in aqueous solutions

We have measured the limiting diffusion coefficients of three different pesticides in aqueous solutions: glufosinate ammonium, cymoxanil and imidacloprid, highly used for tomato production. The experiments were carried in aqueous solutions, at 25 °C, at concentrations below 3 mmol dm−3 (depending on the solubility of pesticides). Mutual diffusion coefficients (D) obtained by using the Taylor dispe

Sweden’s excess mortality in 2020–2022 and reporting in the media

Aim: The aim was to scrutinize the report in March 2023 that Sweden’s excess mortality was lowest in 2020–2022 compared with other European Union and Nordic countries, a report that received great national and international attention. Study design: Comparison of excess mortality in Sweden and Norway. Methods: Excess mortality for 2020–2022 was calculated for Sweden and Norway, the country with per