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Film och historia. Historisk Hollywoodfilm 1960-2000

Popular Abstract in SwedishDenna avhandling studerar relationer mellan film och historia. Tesen som drivs är följande: Film utgör ett i stora delar outnyttjat historiskt källmaterial som alltid säger mer av empiriskt värde om sin produktionskontext än det gör om perioden som skildras. Denna tes bygger vidare på resonemang kring film och historia som genom åren har framlagts av företrädesvis historThe hypothesis put forward in this thesis stipulates that films always say more of empirical value about the time in which they are produced than they do about the periods they depict. The aim is not only to prove that such an idea is valid, but also that it might be transformed into a new and applicable theory in studies of film and history. Here, this is done in contextualized analyses of the pr

Disturbed cholesterol homeostasis in hormone-sensitive lipase null mice.

Transcriptomics analysis revealed that genes involved in hepatic de novo cholesterol synthesis were down-regulated in fed HSL-null mice that had been on high-fat diet (HFD) for 6 months. This finding prompted a further analysis of cholesterol metabolism in HSL-null mice, which was performed in fed and 16-h fasted mice on a normal chow diet (ND) or a HFD regimen. Plasma cholesterol was elevated in

A Climate of Planning: Swedish Municipal Response to Climate Change

This is "an account of variable responses from Swedish municipalities in terms of both adaptation and mitigation measures. By looking at the relationships between national and municipal policies, Langlais examines the adaptation barriers and acknowledges the role of 'visionary individuals' in some municipalities for initiating local actions unders similar institutional and governance conditions. H

Pregnancy-associated acquired haemophilia A: results from the European Acquired Haemophilia (EACH2) registry.

Objective: The European Acquired Haemophilia registry (EACH2) collected data on the demographics, diagnosis, underlying disorders, bleeding characteristics, treatment, and outcome of women with acquired haemophilia A (AHA), a rare and often severe bleeding disorder caused by autoantibodies directed against coagulation factor VIII. Design: Prospective, multi-centre, large-scale, pan-European regi

Kissingstents in the Aortic Bifurcation - a Valid Reconstruction for Aorto-iliac Occlusive Disease.

OBJECTIVE: To evaluate outcome and patency predicting factors of kissingstent treatment for aorto iliac occlusive disease (AIOD). METHODS: Patients treated with kissingstents for AOID between 1995 and 2004 at a tertiary referral center were identified through local databases. Chart review and preoperative images were used for TASC and Fontaine classification. Follow-up consisted of clinical exams,

Breast tomosynthesis and digital mammography: a comparison of diagnostic accuracy.

Objective: Our aim was to compare the ability of radiologists to detect breast cancers using one-view breast tomosynthesis (BT) and two-view digital mammography (DM) in an enriched population of abnormal (diseased) patients and benign and/or normal (healthy) patients. Methods: All participants gave informed consent. The BT and DM examinations were performed with about the same average glandular

Virus Entry via the Alternative Coreceptors CCR3 and FPRL1 Differs by Human Immunodeficiency Virus Type 1 Subtype.

HIV-1 infects target cells by binding to CD4 and a chemokine receptor, most commonly CCR5. CXCR4 is a frequent alternative coreceptor (CoR) in subtype B and D HIV-1 infection, but the importance of many other alternative CoR remains elusive. We have analyzed HIV-1 envelope proteins (Env) from 66 individuals infected with the major subtypes of HIV-1 to determine if virus entry into highly permissiv

Complement inhibitor C4b-binding protein interacts directly with small glycoproteins of the extracellular matrix.

Components derived from cartilage have been suggested to maintain the inflammation in joints in arthritis. Small leucine-rich repeat proteins (SLRPs) are structural components of cartilage important in organizing the meshwork of extracellular matrix components. It has recently been shown that the SLRP fibromodulin interacts with complement initiator C1q, leading to complement activation. The compl

Esophageal Dysmotility is More Common Than Gastroparesis in Diabetes Mellitus and is Associated With Retinopathy.

Gastroparesis is a well-known complication of diabetes mellitus, both in symptomatic and asymptomatic patients. Esophageal dysmotility has also been described, but is not as well-characterized. The etiology and effect of these complications need to be clarified. The aim of the present study was to evaluate esophageal and gastric motility, complications, gastrointestinal symptoms, and plasma biomar

Situational leadership in air traffic control

In high-risk environments such as air traffic control, leadership on different levels plays a certain role in establishing, promoting, and maintaining a good safety culture. The current study aimed to investigate how leadership styles, leadership style adaptability, and over and under task leadership behavior differed across situations, operative conditions, leadership structures, and working task

Compression of the lower trunk of the brachial plexus by a cervical rib in two adolescent girls: case reports and surgical treatment.

ABSTRACT: Presence of a cervical rib in children is extremely rare, particularly when symptoms of compression of the lower trunk of the brachial plexus occur. We present two cases with such a condition, where two young girls, 11 and 16 years of age were treated by resection of the cervical rib after a supraclavicular exploration of the lower trunk of the brachial plexus. The procedure led to succe

Psychosocial working conditions and exhaustion in a working population sample of Swedish middle-aged men and women.

BACKGROUND: Exhaustion is a concept of interest for both occupational health research and stress-disease theory research. The aim of the present study was to explore associations between chronic stressors, in terms of psychosocial working conditions, and exhaustion in a Swedish middle-aged population sample. METHODS: A vocationally active population sample of the Malmö Shoulder and Neck Study coho

Various Antibody Clones of Napsin A, Thyroid Transcription Factor 1, and p40 and Comparisons With Cytokeratin 5 and p63 in Histopathologic Diagnostics of Non-Small Cell Lung Carcinoma.

Histopathologic classification of cancer in the lung is important for choice of treatment. Cytokeratin 5 (CK5), p63, and p40 are commonly used immunohistochemical markers for squamous cell carcinoma, and napsin A (NAPA) and thyroid transcription factor 1 (TTF-1) are markers for adenocarcinoma of the lung. The aim of the present study was to evaluate these 5 markers and to compare different commerc

Wnt-5a-induced phosphorylation of DARPP-32 inhibits breast cancer cell migration in a CREB-dependent manner.

Tumour cell migration plays a central role in the process of cancer metastasis. We recently identified dopamine and cAMP regulated phospho-protein of 32 kDa (DARPP-32) as an anti-migratory phospho-protein in breast cancer cells. Here we link this effect of DARPP-32 to Wnt-5a signalling by demonstrating that recombinant Wnt-5a triggers cAMP elevation at the plasma membrane and Thr34-DARPP-32 phosph

Time domain Green functions for the homogeneous Timoshenko beam

In this paper a wave splitting technique is applied to a homogeneous Timoshenko beam. The purpose is to obtain a diagonal equation in terms of the split fields. These fields are calculated in the time domain from an appropriate set of boundary conditions. The fields along the beam are represented as a time convolution of Green functions with the excitation. The Green functions do not depend on the

Free-to-total prostate-specific antigen ratio as a predictor of non-organ-confined prostate cancer (stage pT3)

Objective: To evaluate whether the free-to-total prostate-specific antigen (F/T-PSA) ratio can be used to differentiate between stage pT2 and pT3 prostate cancer. Material and Methods: A total of 176 consecutive patients from the Goteborg Screening Study (median T-PSA 4.2 ng/ml) who underwent radical prostatectomy (without neoadjuvant hormonal therapy) were included in the study. The pT stage was

On the role of the fusion protein DEK-NUP214 in leukemogenesis

Popular Abstract in Swedish Blodet har en viktig funktion i kroppen. Blodet bildas i den röda benmärgen och består av olika typer av celler med olika specialiserade funktioner, varav många livsnödvändiga. De röda blodkropparna transporterar syre till alla våra kroppsdelar så att våra muskler fungerar och vi orkar gå och springa och så att vår hjärna kan arbeta. De vita blodkropparna hjälper oss atThe t(6;9) translocation is found in a subset of patients with acute myeloid leukemia (AML) and is associated with a poor prognosis. The translocation results in the formation of the DEK-NUP214 fusion protein containing almost the entire nuclear protein DEK and two thirds of the nucleoporin NUP214. The molecular mechanisms behind the leukemic conversion of cells expressing the fusion protein DEK-N