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OBJECTIVE: Employment rates are significantly lower among individuals with arthritis compared to a general population. There is, however, limited research about how men with arthritis perceive their ability to maintain working. The aim of this study was thus to explore their perception of this. PARTICIPANTS: Nine employed men with arthritis were purposively sampled. METHODS: Interviews were perfor
Westergren R, Nilsson D, Heglind M, Arani Z, Grande M, Cederberg A, Ahren B, Enerback S. Overexpression of Foxf2 in adipose tissue is associated with lower levels of IRS1 and decreased glucose uptake in vivo. Am J Physiol Endocrinol Metab 298: E548-E554, 2010. First published December 15, 2009; doi:10.1152/ajpendo.00395.2009.-Many members of the forkhead genes family of transcription factors have
Asthma and allergic rhinitis are diseases that cause major disability and illness in all ethnic groups and ages. It is well established that allergic rhinitis and asthma are closely linked entities and more than 75 % of the patients with asthma reports concomitant rhinitis. Asthma is also closely associated to bronchial hyperresponsiveness, and a large part of patients with rhinitis alone show a r
BACKGROUND: Understanding the role that urologic disease plays within central Haiti could lead to the development of sustainable and regionally appropriate urologic care. We aim to document the prevalence of urologic surgical disease presenting for treatment in central Haiti. METHODS: The present study is based on a retrospective review of surgical case logs at five Partners in Health and Zanmi La
Objective. The current study used islet amyloid polypeptide (IAPP) knockout mice (KO mice) to investigate the physiological role of IAPP in the regulation of food intake (FI). Material and methods. FI and body weight were measured in KO and wild-type (WT) mice for 27 weeks. In an additional short-term experiment, IAPP (25 pmol . kg(-1)min(-1)) was infused subcutaneously for 3 days in KO and WT mic
The ubiquitin-editing enzyme A20 (TNFAIP3) and the deubiquitinase CYLD are central negative regulators of NF-kappa B signaling. Both can act by removing nonproteolytic K63-linked polyubiquitin chains from an overlapping set of signaling molecules. In B cells, A20 deficiency results in hyperactivity, loss of immune homeostasis, inflammation, and autoimmunity. The reported consequences of CYLD defic
Abstract General practice is a broad and multifaceted field of knowledge. Political steering instruments declare that general practice and primary care are characterized by a holistic perspective on the individual, with quality, accessibility, continuity, and cooperation being important factors. For the last few decades, quality assurance has been in focus in Swedish health care. Inspiration has c
Background: Day centres are central for community participation among people with mental health problems. Understanding day centre attendees' occupational engagement is therefore important. Method:A total of 88 people from six day centres in four municipalities in southern Sweden completed a time-use diary, recording their occupational engagement during the most recent day at the day centre. The t
Learning from incidents is considered a very important source for learning and improving safety in the process industries. However, the effectiveness of learning from reported incidents can often be ques-tioned. Therefore, there is a need to be able to evaluate the effectiveness of learning from incidents, and for that purpose we need methods and tools. In this paper, a method is described for eva
Chronic oro-facial pain conditions such as persistent idiopathic facial pain (PIFP), atypical odontalgia (AO) and burning mouth syndrome (BMS), usually grouped together under the concept of idiopathic oro-facial pain, remain a diagnostic and therapeutic challenge. Lack of understanding of the underlying pathophysiological mechanisms of these pain conditions is one of the important reasons behind t
"When we celebrate the days of our deceaced brothers" -- texts for the Office of the dead in Liber daticus vetustior
Low-intensity laser prepulses (<10(13) W cm(-2), nanosecond duration) are a major issue in experiments on laser-induced generation of protons, often limiting the performances of proton sources produced by high-intensity lasers (approximate to 10(19) W cm(-2), picosecond or femtosecond duration). Depending on the intensity regime, several effects may be associated with the prepulse, some of which a
Syria, as well as many other countries in the Middle East, faces serious water shortage problems. Available water per capita (AWPC) will dramatically decrease due to climate change, population increase, and water needed for economic growth. Rainwater harvesting can play an important role in increasing available water in Syria. However, the absence of rainwater sewer systems in many rural areas in
There is a knowledge gap with regard to the structure of the care and service system available to persons with dementia. This is very much a concern for nurses who are the main providers in the care of dementia. The study, a part of the "RightTimePlaceCare" project, describes the development and content of a mapping system aimed at exploring the content of care and service for persons with dementi
Popular Abstract in Swedish Stroke är en sjukdom som främst drabbar äldre och är den största anledningen till att människor får olika slags handikapp såsom förlamning och afasi. Det finns ännu ingen effektiv behandling för att lindra symtom och lidande efter en stroke, förutom rehabilitering, och därför kostar stroke samhället enormt mycket pengar. Befolkningen blir allt äldre, vilket även medför Cell replacement by neural transplantation can, in animal models of neurodegenerative diseases, reconstruct damaged brain circuitry. In the clinical situation, the graft material used for cell therapy must, most likely, be of human origin. The human fetal brain is one potential source of neural stem cells (NSCs) for cell replacement therapy in neurodegenerative disorders such as stroke. Stroke is
Popular Abstract in Swedish Äggstockarna genomgår förändringar under en normal menstruationscykel. I samband med tumörväxt i äggstockarna utvecklas nya blodkärl. Dessa förändringar kan upptäckas med både tvådimensionellt (2D) och tredimensionellt (3D) gråskale- och Doppler-ultraljud. Med Doppler-ultraljud kan man upptäcka blodkärl och uppskatta blodflödeshastigheterna i blodkärlen. Referensvärden The aims of this work were: 1) to estimate the number of follicles, ovarian volume and power Doppler vascular indices and their changes with age using three-dimensional (3D) transvaginal grey-scale and power Doppler ultrasound in asymptomatic women of fertile age either with natural menstrual cycles or using combined oral contraceptives, and 2) to determine whether tumour vascularity, assessed by
All is a 17-kDa chromosomally encoded outer membrane protein that mediates serum resistance (complement resistance) in the pathogenic Yersiniae (Yersinia pestis, Y. enterocolitica, and Y. pseudotuberculosis). In this article, we demonstrate that Y pseudotuberculosis Ail from strains PB1, 2812/79, and YPIII/pIB1 (serotypes O:1a, O:1b, and O:3, respectively) can bind the inhibitor of the classical a
The globular protein γB-crystallin exhibits a complex phase behavior, where liquid-liquid phase separation characterized by a critical volume fraction ϕc = 0.154 and a critical temperature Tc = 291.8 K coexists with dynamical arrest on all length scales at volume fractions around ϕ ≈ 0.3-0.35, and an arrest line that extends well into the unstable region below the spinodal. However, although the s
