Filetype
Systemic lupus erythematosus (SLE) and systemic sclerosis (SSc) are two severe autoimmune connective tissue diseases. The fundamental knowledge about their aetiology is limited and the conditions display complex pathogenesis, multifaceted presentations, and unpredictable courses. Despite significant efforts, the lack of fully validated biomarkers enabling diagnosis, classification, and monitoring
BACKGROUND: Simultaneous contact allergies to the reactive diluent phenyl glycidyl ether (PGE) and epoxy resins based on diglycidyl ether of bisphenol A (DGEBA) or epoxy resins of the bisphenol F-type have been reported. The latter epoxy resins contain three isomers of diglycidyl ether of bisphenol F (DGEBF). PGE, DGEBA, and DGEBF are chemically similar with respect to the reactive glycidyl group
Sweden, with a high level of political participation and an avant-garde position regarding internet access, broadband and social media penetration in the population, is a critical case for studying social media in relation to political participation. Three types of users – members of political parties, members of interest organizations, and non-members – are interviewed in focus groups about their
Reports on the retention of somatic cell memory in induced pluripotent stem cells (iPSCs) have complicated the selection of the optimal cell type for the generation of iPSC biobanks. To address this issue we compared transcriptomic, epigenetic, and differentiation propensities of genetically matched human iPSCs derived from fibroblasts and blood, two tissues of the most practical relevance for bio
PURPOSE: This review aims to provide guidance in managing glaucoma patients more effectively. It focuses on the importance of detecting progression and measuring its rate within the management of primary open-angle glaucoma today. Recent findings strongly indicate that continued monitoring of visual fields (VFs) and reassessment of target intraocular pressures (IOPs) depending on VF progression ra
Objectives. SLE is a systemic autoimmune disease with an annual incidence of 3.8 per 100 000. Several pathogenic mechanisms are believed to be operating in SLE, including an impaired clearance of apoptotic cells, activation of the type I IFN pathway and generation of autoimmune leucocytes. Growth arrest-specific protein 6 (Gas6) and its receptor Axl are known to regulate inflammation and may be im
Excited state lifetimes of c(4)('1)Sigma (+)(u), upsilon = 0-2 states of molecular nitrogen have been determined in a laboratory investigation using a picosecond XUV laser in a pump-probe configuration. For c(4)('1)Sigma (+)(u) upsilon = 0 the lifetime is tau = 740 +/- 50 ps, for the lowest rotational states. For higher rotational states a gradual shift towards tau = 495 ps is found in agreement w
In dense passive radio frequency identification (RFID) systems, code division multiple access (CDMA) techniques can be used to alleviate severe collisions and thus enhance the system performance. However, conventional CDMA techniques are challenging to implement, especially for passive tags due to cost and power constraints. In this paper, we design a CDMA-based multi-reader passive ultra high fre
I. Levi has advocated a decision-theoretic account of belief revision. We argue that the game-theoretic framework of Interrogative Inquiry Games, proposed by J. Hintikka, can extend and clarify this account. We show that some strategic use of the game rules (or ‘policies’) generate Expansions, Contractions and Revisions, and we give representation results. We then extend the framework to represent
Two different mathematical methods of implementing a detailed kinetic soot model have been employed in this work. The theoretical description of the soot modeling employed in this work is divided into three parts. Initially a detailed kinetic soot model is described from a chemistry and physics perspective. The soot model is then elaborated into mathematical form, starting with the formulation of
Isothermal calorimetry and diffuse reflectance infrared DR–FTIR spectroscopy are combined to correlate evolutions of spectroscopic signatures with rates of chemical reactions as reflected in the rate of heat emitted during the first 38 h of cement hydration. Portland limestone cement mortar is employed and the analysis is repeated for two different mixing procedures. Intensive blender mixing with
Background and aims-Laser induced fluorescence (LIF) from colonic mucosa was measured in vivo with and without delta aminolevulinic acid (ALA) in an attempt to differentiate between neoplasia and non-neoplasia in real time during colonoscopy. Methods-Spectra from 32 adenomas, 68 normal sites, and 14 hyperplastic polyps in 41 patients were obtained with a point monitoring system. Twenty one of the
First laser spectroscopic investigations on atomic selenium are reported. Natural selenium was thermally dissociated in a quartz resonance cell keeping the background pressure of abundant selenium molecules low by differential heating. The 4p35s5S2 level was excited by frequency-tripled pulsed-dye laser radiation at 207 nm. From time-resolved recordings of the fluorescence decay at 216 nm a natura
