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To verify and re-emphasise the efficacy of the max electrogram-guided approach for ablation of cavotricuspid isthmus (CTI)-dependent atrial flutter (AFL).
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To verify and re-emphasise the efficacy of the max electrogram-guided approach for ablation of cavotricuspid isthmus (CTI)-dependent atrial flutter (AFL).
Group A streptococci (GAS) cause, among other infections, pharyngotonsillitis in children. The species is frequently localized with the Gram-negative respiratory pathogens non-typeable Haemophilus influenzae (NTHi) and Moraxella catarrhalis, which both produce outer membrane vesicles (OMVs). The aim of this study was to investigate whether OMVs isolated from NTHi contain functional β-lactamase and
Aims: The need to combine active employment and parenthood is a reality for many parents today. Knowing more about which work place factors are associated with better or worse health could help employers to form a work environment that provides optimal conditions to maintain or increase health and work engagement in this group. The aim of this study was to explore possible associations between dif
Orthostatic hypotension (OH) is a relatively common heterogenous and multifactorial disorder, traditionally classified as neurogenic (less common but often more severe), or non-neurogenic (more common, with no direct signs of autonomic nervous system disease). The different clinical variants of orthostatic intolerance include initial, classical and delayed OH as well as postural tachycardia syndro
The shortage of donor lungs restricts the number of lung transplantations that can be performed. However, extension of the donor pool using organs donated after cardiac death (DCD) could potentially increase the number of patients who undergo transplantation. To establish acceptance among hospital personnel and the donor's next of kin for the uncontrolled DCD procedure we proposed a simplified pre
During recent years, dipeptidyl peptidase-4 (DPP-4) inhibition has been included in the clinical management of type 2 diabetes, both as monotherapy and as add-on to several other therapies. DPP-4 inhibition prevents the inactivation of the incretin hormones, glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1). This results in stimulation of insulin secretion and
We highlight some results from our detailed abundance analysis study of 703 kinematically selected F and G dwarf stars in the solar neighbourhood. The analysis is based on spectra of high-resolution (R = 45 000 to 110 000) and high signal-to-noise (S/N approximate to 150 to 300). The main findings include: (1) at a given metallicity, the thick disk abundance trends are more alpha-enhanced than tho
The thiopurines are widely used in the treatment of inflammatory bowel disease, but are limited by poor dose-effect relationship. The objective was to assess the ability of a novel assay, determining the mono-, di-, and triphosphates, of thioguanine as well as methylthioinosine as individual metabolites in erythrocytes, to predict clinical outcome compared to a routine assay, determining metabolit
Flame flashback from the combustion chamber to the premixing section is a major operability issue when using high H-2 content fuels in lean premixed combustors. Depending on the flow-field in the combustor, flashback can be triggered by different mechanisms. In this work, three flashback mechanisms of H-2/CH4 mixtures were visualized in an atmospheric variable-swirl burner using high speed OH* che
Autoantibodies to GAD65 (GAD65Ab) are prominent in type 1 diabetes. These autoantibodies may be present both years before and after the clinical diagnosis of type 1 diabetes and are widely used as a marker for the disease. Recently it has been demonstrated that progression to type 1 diabetes is accompanied by GAD65Ab epitope maturation. Here we examine whether autoantibody maturation processes als
Action spectroscopy is a method for identifying the light-absorbing chromophore in a photobiological or biochemical process by comparing the efficiency of radiation of different wavelengths in driving the process. This chapter explains the principle and gives several ex-amples from the history of biology of what has been achieved using this technique.
The popular image of archaeology and what archaeologists do is based on various clichés which emphasise, among other things, adventurous fieldwork, the discovery of treasures and historical detective work. Although archaeologists may see themselves differently, their image in popular culture reveals a lot about how the subject is perceived and why it is so widely appreciated at present. I suggest