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Autoantibodies to GAD65 (GAD65Ab) are prominent in type 1 diabetes. These autoantibodies may be present both years before and after the clinical diagnosis of type 1 diabetes and are widely used as a marker for the disease. Recently it has been demonstrated that progression to type 1 diabetes is accompanied by GAD65Ab epitope maturation. Here we examine whether autoantibody maturation processes als

Action spectroscopy is a method for identifying the light-absorbing chromophore in a photobiological or biochemical process by comparing the efficiency of radiation of different wavelengths in driving the process. This chapter explains the principle and gives several ex-amples from the history of biology of what has been achieved using this technique.

The popular image of archaeology and what archaeologists do is based on various clichés which emphasise, among other things, adventurous fieldwork, the discovery of treasures and historical detective work. Although archaeologists may see themselves differently, their image in popular culture reveals a lot about how the subject is perceived and why it is so widely appreciated at present. I suggest

Requirements on well documented management systems for Nuclear Power Plants (NPPs) are relatively new and in different developmental phases. Thus there is a need of knowledge about well-functioning Safety Management Systems (SMSs) also considering other goals and restrictions. Since there ia a lack of mature management systems for NPPs it is important to learn from other NPPs, but also from other

In the last decades there has been an increased influence of ethnomusicology in music education research. This is reflected in the activities of international associations such as International Society for Music Education (ISME), International Music Council (IMC) and Cultural Diversity in Music Education (CDIME), as well as in a growing body of research (e.g. Drummond, 2005; Schippers, 2010; Szego

The existence of sesquisyllabic words consisting of one 'minor' and one 'major' syllable is often mentioned as a characteristic property of the Mon-Khmer language group, but the existence of contrastive tones on minor syllables has been described only for (Northern) Kammu. In this article we investigate the acoustic properties of the the minor syllable tones, and also give a brief overview of thei

There are many possible definitions of “technology” and I will discuss some of these in this book. However, in this introduction let me use a definition of Svante Lindqvist who defines technology very intuitively as “those activities, directed towards the satisfaction of human wants, which produce change in the material world.” He says also “the distinction between human “wants” and more limited h

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