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AIMS: Women with arrhythmogenic right ventricular cardiomyopathy (ARVC) are at relatively lower risk of ventricular arrhythmias (VAs) than men, but the physical burden associated with pregnancy on VA risk remains insufficiently studied. We aimed to assess the risk of VA in relation to pregnancies in women with ARVC. METHODS AND RESULTS: We included 199 females with definite ARVC (n = 121) and muta
Nordic noir is an emerging crime genre that draws on crime fiction, feature film, and television drama. The term Nordic noir is associated with a region (Scandinavia), with a mood (gloomy and bleak), with a look (dark and grim), and with strong characters and a compelling narrative. Such is the popularity of Nordic noir as a brand for crime that it can also, and somewhat confusingly, be associated
The objective of this review is to examine how drug spending in different age groups changed during the 1990s. Time series analysis of registered data on prescription drug spending were performed, along with two decompositions, one of which was spending in three components: price, quantity (defined daily dose) and residual. The size of the residual is a measure of the impact of changes in drug tre
Background: Heart function following heart transplantation (HTx) is influenced by numerous factors. It is typically evaluated using transthoracic echocardiography, but reference values are currently unavailable for this context. The primary aim of the present study was to derive echocardiographic reference values for chamber size and function, including cardiac mechanics, in clinically stable HTx
In previous in-vivo studies we have presented indirect evidence for the involvement of islet acid glucan-1,4-alpha-glucosidase (acid amyloglucosidase), a lysosomal glycogen-hydrolysing enzyme, in certain insulin secretory processes. In the present combined in-vitro and in-vivo investigation, we studied whether differential changes in islet acid amyloglucosidase activity were related to the insulin
AIM: Although metformin treatment has been reported to reduce the risk of cardiovascular events in patients with type 2 diabetes, the underlying mechanisms have not been elucidated fully. Here we assessed atherosclerotic lesion formation in newly established 2 mouse lines with different blood glucose levels (Oikawa-Nagao Diabetes-Prone [ON-DP] and -Resistant [ON-DR]) to evaluate the effect of metf
Objective: The aim of this study was to explore the "Birth Attitude Profile Scale (BAPS)" in a selected sample of women with fear of birth. Another aim was to develop profiles of women according to their birth attitudes and levels of childbirth fear in relation to background characteristics.Methods: A secondary analysis of data collected in two different samples of women with fear of birth. Data w
BACKGROUND: Both persons with intellectual disability (ID) and persons with dementia have high disease burdens, and consequently also high health care needs. As life expectancy increases for persons with ID, the group of persons with the dual diagnosis of ID and dementia will become larger.METHOD: Through national registries, we identified 7936 persons who had received support directed to persons
BACKGROUND: Personality traits influence health-related quality of life (HRQoL) in Parkinson's disease (PD). Further, an individual's personality traits can influence the strategies they use to cope with a particular stressful situation. However, in PD, the interplay between personality traits, choice of coping strategy, and their subsequent effect on HRQoL remains unclear.OBJECTIVE: The objective
A recent measurement of the lifetime of the excited 3p5 state in the S- negative ion, which is dominated by a forbidden magnetic dipole transition to the 2 P3/ 2 ground state, reveals a discrepancy with earlier theoretical predictions. To investigate this we have performed systematic and large-scale multiconfiguration Dirac-Hartree-Fock calculations for this system. After including a careful treat
The distribution of exoplanet masses is not primordial. After the initial stage of planet formation, gravitational interactions between planets can lead to the physical collision of two planets, or the ejection of one or more planets from the system. When this occurs, the remaining planets are typically left in more eccentric orbits. In this report we demonstrate how the present-day eccentricities
Background/Objectives: High-fat diet consumption is known to trigger an inflammatory response in the hypothalamus, which has been characterized by an initial expression of pro-inflammatory genes followed by hypothalamic astrocytosis, microgliosis, and the appearance of neuronal injury markers. The specific effects of high-fat diet on hypothalamic energy metabolism and neurotransmission are however
Objective: ACTH is considered a weak marker for autonomous cortisol secretion (ACS) in patients with adrenal incidentalomas (AIs). Our aim was to investigate suppressed basal ACTH as a marker of ACS and to elucidate why this criterion is of limited value. Methods: Basal ACTH and cortisol after overnight dexamethasone suppression test (cortisolONDST) were measured in 198 patients with unilateral AI
OBJECTIVES: To analyze whether hospitalization for a psychiatric disorder predicts Parkinson's disease (PD) in men and women in different age groups after accounting for socioeconomic status and geographical region.METHODS: Data from the MigMed database were used to identify all people in Sweden hospitalized for psychiatric disorder and PD during the study period (1987 to 2001). Standardized incid
The authors report the observation of very-high-order odd harmonics of Nd:YAG laser radiation in rare gases at an intensity of about 1013 W cm-2. Harmonic light as high as the 33rd harmonic in the XUV range (32.2 nm) is generated in argon. The key point is that the harmonic intensity falls slowly beyond the fifth harmonic as the order increases. Finally, a UV continuum, beginning at 350 nm and ext
