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Bioreduction has emerged over the years as an alternative method to organic synthesis for the generation of chiral precursors of commercial interest. Bioreductions operate under mild conditions of pH and temperature with the help of highly regio- and enantio-selective oxidoreductase enzymes.In this contribution, the different oxidoreductase families involved in bioreductions are exemplified and th

Injuries to the spinal column and spinal cord are a major cause of disability, affecting predominately young, healthy individuals. The majority of the spinal injuries (60%) affect young healthy males between 15 and 35 years of age, with important socioeconomic consequences, and the costs of lifetime care and rehabilitation are extremely high. As the longevity of the general population increases, t

Experiments were performed to examine the effects of the properties of the aerosol and trace gases in the airmassflowing into cloud on the microphysics and chemistry of the cloud and to investigate the role of the cloud in modifying the properties of the aerosol and trace gases emerging downwind of the cloud system. Measurements of the aerosol properties were made at out of the cloud sites both up

Tumor-associated macrophages (TAMs) are attractive targets for immunotherapy. Recently, studies in animal models showed that treatment with an anti-TAM antibody directed against the scavenger receptor MARCO resulted in suppression of tumor growth and metastatic dissemination. Here we investigated the expression of MARCO in relation to other macrophage markers and immune pathways in a non-small cel

Questions concerning the occurrence of adaptive sex ratio manipulation have a long research tradition in evolutionary biology, but evidence from birds is scarce. It has been suggested that birds are unable to adaptively determine the sex of their young because of the constraints of their sex determination systems. Here we report results from a study of variation in offspring sex ratio in the blue

This chapter examines the very beginning of the criminology of white-collar and corporate crime by focusing on Edwin Sutherland and his "discovery" of the concept of white-collar crime. Sutherland's contributions to the criminology of white-collar crime, beginning with his 1939 American Sociological Society presidential address and culminating with the publication of his book White Collar Crime, c

Background: Occupational therapists increasingly encounter clients from diverse cultural backgrounds and need to meet their professional obligation of delivering culturally competent practice. Yet the process of cultural competency is poorly understood in occupational therapy practice. There is a need for a clear understanding of the meaning and process of cultural competency as it is enacted in p

The genomes of lungfish, together with those of some urodele amphibians, are the largest of all vertebrate genomes. It has been assumed that the bulk of the DNA making up these large genomes has been derived from repeat elements, like the noncoding DNA of those genomes that have been sequenced (e.g., human). In an attempt to characterize repeat sequences in the lungfish genome, we have isolated, b

The influence of wind is only occasionally accounted for in fire safety engineering, still the effect of wind on, for example, the performance of a smoke management system can be large. A simple analytical method to account for the effect of wind on mass flow through horizontal openings for natural ventilation is compared to results from CFD simulations in this paper. It is seen that the correspon

This paper describes how qualitative research methods, particularly action research case studies, can contribute to further advance and develop logistics research. The paper also describes limitations with the current dominance of quantitative (especially survey) research in logistics. However, the paper is not a pure criticism of the use of quantitative research methods in general or in logistics

AbstractBackgroundMotion tracking during live surgeries may be used to assess surgeons’ intra-operative performance, provide feedback, and predict outcome. Current assessment protocols rely on human observations, controlled laboratory settings, or tracking technologies not suitable for live operating theatres. In this study, a novel method for motion tracking of live open-heart surgery was develop

The paradigm shift of focus from rental apartments to owner-occupied units on the Swedish property market has led to a substantial number of rental apartments being converted to cooperative apartments. Such conversions are typically done at prices below market value. This provides strong financial incentives for tenants involved in such a conversion to use their informational advantage regarding t

OBJECTIVE: To evaluate circumferential resection margin (CRM) as a risk factor for distant metastasis (DM) in rectal cancer.SUMMARY BACKGROUND DATA: The treatment of rectal cancer has evolved over the last decades. Surgical radicality is considered the most important factor in preventing recurrences including local and distant. CRM ≤1.0 mm is considered to increase recurrence risk. This study expl