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Objectives: The enormous burden that cardiovascular diseases put on individuals and societies warrants reliable biomarkers of disease risk to optimize disease prevention. We studied longitudinal movement (LMov) in arterial walls using ultrasound of the common carotid artery (CCA). We believe that LMov could be a sensitive biomarker of cardiovascular health and in this study, we evaluate the intra-

Background: Two risk factors for severe retinopathy of prematurity (ROP) in extremely preterm infants are thrombocytopenia and low levels of arachidonic acid (AA) and docosahexaenoic acid (DHA). To date, these risk factors have not been linked. Method: Infants born < 28 weeks gestational age (GA) from 2016 to 2019 were randomized to postnatal enteral AA/DHA supplementation or standard care (contro

Drought is a climate risk that affects access to safe water, crop development, ecological stability, and food production. Therefore, developing drought prediction methods can lead to better management of surface and groundwater resources. Similarly, machine learning can be used to find improved relationships between nonlinear variables in complex systems. Initially, the standardized precipitation

Familial Platelet Disorder with associated Myeloid Malignancy (FPDMM, FPD/AML, RUNX1-FPD), caused by monoallelic deleterious germline RUNX1 variants, is characterized by bleeding diathesis and predisposition for hematologic malignancies, particularly myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). Clinical data on FPDMM-associated AML (FPDMM-AML) are limited, complicating evidence

Background and Objectives: Temporomandibular disorders (TMDs) is an umbrella term for pain and dysfunction involving jaw muscles and/or the temporomandibular joint, with whiplash trauma suggested to be one risk factor. The aim was to evaluate prevalence and relative risk of TMDs in the acute and chronic stages after whiplash trauma. Databases and Data Treatment: This review was registered in Prosp

Kolloider är partiklar i storleksordningen nm till μm. De är viktiga i biologiska system, där exempelvis proteiner är en typ av kolloid. Att studera kolloider ger oss därför insikt i hur till exempel proteiner byggs upp och interagerar. I detta fall försökte vi tillverka kolloidala molekyler, alltså kolloider som interagerar med varandra genom ett specifikt antal bindningar i väl definierade positThe ability of thermoresponsive, amine-functionalized microgel particles to take part in microgelmicrogel inter-cross-linking has previously been reported in the literature, in connection to applications such as for example the formation of stimuli-responsive colloidal gels and colloidosomes [1]. This thesis deals with the synthesis of such thermoresponsive, cross-linkable microgels and their subs

Ett liv utan socker Det finns få av oss som ärligt kan säga att de aldrig bantat eller i alla fall aldrig tänkt på maten de äter och hur mycket de tränar. I vårt utseendefixerade samhälle där modet, att se slankast ut eller ha mest muskler är det svårt att erkänna att man älskar att äta pizza två gånger i veckan. Eller att man struntat i den där gruppträningen kl 17 en tisdag för att sitta hemma

Purpose: Improvements in mortality rate of glioblastoma patients have been limited during the past decades, due to the tumor’s rapidly growing and infiltrative behavior and resistance to current therapy. Recent findings show that higher brain mean dose strongly correlates with inferior overall survival and that local recurrences mainly occur centrally in previously irradiated regions. This project

Klimatförändringarna, energikrisen och en ökande efterfrågan på el har uppmärksammat behovet av en hållbar omställning av energisystemet. Havsbaserad vindkraft spelar en viktig roll i denna omställning och förväntas expandera kraftigt globalt, i EU och i Sverige. Samtidigt möter projekt stort lokalt motstånd. Trots att svenskar generellt visar högt stöd för vindkraft så har en majoritet av de senaClimate change, the energy crisis of 2022-2023, and estimations of future electricity demands have stressed the necessity for a rapid transition of the energy system. Offshore wind energy plays an important role in this transition, and is expected to expand considerably on a global level, in the EU and in Sweden. While Swedes show high support of wind energy, a majority of recent projects have bee

Background and purpose — Traditional surgery forarthritis of the distal radioulnar joint (DRUJ), which typicallyinvolves resecting the ulnar head, is being increasingly challengedby newer techniques, such as prosthetic ulnar headreplacement. The aim of our prospective cohort study was toinvestigate the clinical and patient-reported functional results,up to 2 years postoperatively, among patients w

Background: The coronavirus disease-2019 (COVID-19) pandemic posed pronounced challenges in the care of lung transplant (LTx) recipients. Global variations in containment strategies and the introduction of messenger ribonucleic acid (mRNA) vaccines have sparked extensive debate in both scientific and public arenas. Methods: This retrospective study compared outcomes among LTx recipients in Denmark

The lifelong risk of stroke following adverse pregnancy outcomes, and potential causality, are unknown. This study examined five major adverse pregnancy outcomes and long-term risk of stroke in a large population-based cohort. Methods A national cohort study was conducted of all 2 201 393 women with a singleton delivery in Sweden during 1973–2015, followed up for stroke through 2018. Cox regressio

Background Primary ciliary dyskinesia (PCD) represents a group of rare hereditary disorders characterised by deficient ciliary airway clearance that can be associated with laterality defects. We aimed to describe the underlying gene defects, geographical differences in genotypes and their relationship to diagnostic findings and clinical phenotypes. Methods Genetic variants and clinical findings (a

PURPOSE: This study aimed to examine the associations between the intake of high- and low-fat fermented dairy (cheese and fermented milk), their proteomic profiles, and mortality risk.METHODS: This cohort study included 25,187 participants (mean age 57.7 years, 60.9% females). Fermented dairy intake was assessed by a modified diet history method. In a random subset of this cohort (n = 4359), we co

Background: Studies on long-term exposure to air pollution at high levels suggest an association with increased risk of metabolic syndrome (MetS). We aimed to study this relationship at very low levels, less well-studied, yet of public health importance. Methods: The Swedish CArdioPulmonary bioImage Study (SCAPIS) consists of randomly selected subjects aged 50–64 years from six large cities in Swe

BACKGROUND: Post-acute sequelae of SARS-CoV-2 infection, or long COVID, include diverse symptoms and remain a major concern worldwide. This study investigates the occurrence of depression, anxiety, fatigue, and headache 1 year prior to the COVID-19 pandemic (2019), 12 months prior to, and 6 months after long COVID diagnosis in individuals diagnosed with long COVID and matched population-based cont

Background: We set out to profile the immune mechanisms active in treatment-naïve oligoarticular JIA (oJIA) to improve the knowledge of its immunopathogenesis, to identify potential biomarkers that can aid diagnosis, predictions and that correlate with clinical disease parameters. Methods: Using Olink proteomics (inflammation panel measuring 92 markers), we defined and compared the inflammation pr

Forward osmosis (FO) and membrane distillation (MD) have emerged as promising processes for seawater desalination. One of the key factors influencing the FO process is the selection of a suitable draw solution (DS), which should exhibit high osmotic pressure and easy regeneration through a secondary process such as MD. Thermo-responsive polymers having ethylene oxide (EO) and propylene oxide (PO)