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Horizontal gene transfer (HGT) is a major driver of evolution and a key source of innovation in the microbial world. Mobile genetic elements (MGEs), such as plasmids and phages, often act as agents of HGT or as vehicles for cargo genes, some of which define the adaptive potential of the host organism in specific environments. These genes are involved in immunity, anti-immunity, virulence, and anti
The Chicxulub impact triggered a massive extinction event marked by the Cretaceous-Paleogene boundary (K-Pg ∼66Ma), ejecting vast amounts of dust, molten, and vaporized materials. While impact spherules are interpreted as products of impactor and target lithologies, their precise composition and distribution remain insufficiently constrained. Although previous studies restrict impactor contaminati
Disturbance of ecosystems is a major factor in regional carbon budgets, and it is believed to be partly responsible for the large inter-annual variability of the terrestrial part of the carbon balance. Forest fires have so far been considered as the most important disturbance but also other forms of disturbance such as insect outbreaks or wind-throw might contribute significantly to the largely un
In areas where tectonics and weathering have hydrogeological significance, electrical methods can assist in mapping the subsurface. In this work, resistivity imaging was used to map fractures, faults and quartz veins emplaced in strongly weathered volcanic rocks. The aim was to map geological units related to the formation of groundwater systems in the Rio Artiguas basin, Nicaragua. Eight 2D resis
Myogenic activity, distention of the detrusor, and signals from the urothelium may initiate voiding. In the bladder, afferent nerves have been identified not only in the detrusor, but also suburothelially, where they. form a plexus that lies immediately beneath the epithelial lining. Extracellular adenosine triphosphate (ATP) has been found to mediate excitation of small-diameter sensory neurons v
The Carex flava complex ( Cyperaceae) was used as a model system in a study of the effects of variation in species delimitation on genetic diversity estimates. The whole complex constitutes a syngameon within which gene flow may occur between taxa. Several more or less distinct evolutionary lineages in the complex are morphologically similar to each other and are often combined into broadly define
Cystatin C, a major extracellular cysteine proteinase inhibitor, is deposited as amyloid in brain haemorrhage patients with hereditary cystatin C amyloid angiopathy (HCCAA). A disease-causing mutation on the genetic level results in the substitution Leu68-->Gln (L68Q) in cystatin C, which causes protein instability. Besides carrying the L68Q substitution, cystatin C in amyloid deposits isolated fr
Acute myeloid leukemia (AML) with inv(16)(p13q22) or the variant t(16;16)(p13;q22), is strongly associated with the FAB subtype M4Eo. A high incidence of CNS involvement was reported in the 1980s, but otherwise little is known about the pattern of extamedullary leukemia (EML) manifestations in this AML type. We have compiled clinical and cytogenetic data on 27 consecutive AML cases with inv(16)/t(
Nitrogen deposition and intentional forest fertilisation with nitrogen are known to affect the species composition of ectomycorrhizal fungal communities. To learn more about the mechanisms responsible for these effects, the relations between fungal growth, nitrogen uptake and nitrogen availability were studied in ectomycorrhizal fungi in axenic cultures and in symbiosis with pine seedlings. Effect
Fine-grained tills are a dominant feature of the drift geology of Sweden. Until recently their use in earthworks applications has been limited due to the plentiful supply of naturally occurring gravel and crushed rock, and their high sensitivity to moisture content change which often leads to the view that fine-grained tills are problem soils. Environmental and economic factors are, however, leadi
To investigate the Holocene vegetation history and shoreline displacement along the southeastern Swedish coast, two radiocarbon dated pollen, macrofossil and mineral magnetic sequences were studied in the western Blekinge coast: Hunnemara Lake and Smygen Bay. Both pollen records show mosaic vegetation with grasslands, heaths and woodlands prior to 11 300 cal. BP. Pinus-dominated mixed forest was i
Particle emissions from residential wood combustion in small communities in Northern Sweden can sometimes increase the ambient particle concentrations to levels comparable to densely trafficked streets in the center of large cities. The reason for this is the combination of increased need for domestic heating during periods of low temperatures, leading to higher emission rates, and stable meteorol
We analyzed a comprehensive set of single-nucleotide polymorphisms (SNPs) and length polymorphisms in the interferon regulatory factor 5 (IRF5) gene for their association with the autoimmune disease systemic lupus erythematosus (SLE) in 485 Swedish patients and 563 controls. We found 16 SNPs and two length polymorphisms that display association with SLE (P < 0.0005, OR > 1.4). Using a Bayesian mod
Copolymers of N-acryloyl-m-aminophenylboronic acid (NAAPBA) with acryamide (AA), N,N-dimethylacrylamide (DMAA), and N-isopropylacrylamide (NIPAM) were found to adsorb on cross-linked agarose gel (Sepharose CL-6B) in the pH range from 7.5-9.2, due to specific boronate-sugar interactions. The molar percentages of phenylboronic acid (PBA) groups in the boronate-containing copolymers (BCCs), as estima
Feeding, reproduction and accumulation of cyanobacterial toxins by the calanoid copepods Acartia bifilosa and Eurytemora affinis were studied during a cruise in the northern Baltic Sea. The experiments were carried out using both mixtures of natural plankton communities, mixtures containing the toxic Nodularia spumigena, and diets containing only the toxic cyanobacterium. Both copepod species had
