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The early Middle Ages saw the formation of the three Nordic kingdoms of Sweden, Norway and Denmark, and at that time the area studied here constituted a border region between them. During the same period the Church was very active in the area: a bishopric was established and a large number of churches were built. This makes the area a particularly interesting one to study from the point of view of
Popular Abstract in Swedish Moraxella catarrhalis är en bakterie som man länge trodde var en del av vår normala bakterieflora och därmed ofarlig. Under de senaste tjugo åren har M. catarrhalis dock visat sig vara en av orsakerna till öroninflammation hos barn och lägre luftvägsinfektioner hos vuxna med någon annan underliggande sjukdom som t.ex. kronisk obstruktiv lungsjukdom (KOL). De senaste 10 Moraxella catarrhalis is frequently colonizing the human respiratory tract, particularly in children. This gram-negative bacterium has during the last two decades been recognized as a pathogen causing otitis media in children and lower respiratory tract infections in adults with predisposing conditions such as chronic obstructive pulmonary disease (COPD). The virulence determinants of M. catarrhal
Interleukin 6 (IL-6) is a multifunctional cytokine and a potent stimulator of bone resorption and has been implicated in the pathogenesis of osteoporosis in postmenopausal women. The aim of this study was to investigate if a functional JL-6 promoter polymorphism (-174) was related to bone mass and fractures in a cohort consisting of 964 postmenopausal Caucasian women aged 75 years. Bone mineral de
Popular Abstract in Swedish Avhandlingen handlar om hur radiovågor tar sig fram i miljöer där saker som hus, väggar och fönster är i vägen. Framför allt ligger fokus på hur signalen från en sändare placerad utomhus kan nå fram till en mobil terminal (t. ex. en mobiltelefon) som befinner sig inomhus. Hur mycket signalen dämpas när den passerar väggen är av stor betydelse när man ska avgöra hur långThis thesis deals with radio wave propagation in environments where the propagation is severely influenced by surrounding objects, mainly walls and other building structures. As an introduction, a brief description is given on propagation terms like loss, delay and dispersion along with system functions relevant for the topic. The focus is then placed on propagation from an outdoor transmitter to
PURPOSE. To study the possible involvement of the rod (SLC24A1) and cone (SLC24A2) Na-Ca+K exchanger (NCKX) genes in retinal diseases. METHODS. DNA was collected from unrelated patients with retinal disease, mainly from North America. A human genomic library was screened with the cone NCKX cDNA, and hybridizing clones were sequenced to determine the genomic organization of the SLC24A2 gene. The si
Background: Insulin is a therapeutic protein that is widely used for the treatment of diabetes. Its biological function was discovered more than 80 years ago and it has since then been characterized extensively. Crystallization of the insulin molecule has always been a key activity since the protein is often administered by subcutaneous injections of crystalline insulin formulations. Over the year
Atmospheric inversions are used to derive constraints on the net sources and sinks of CO2 and other stable atmospheric tracers from their observed concentrations. The resolution and accuracy that the fluxes can be estimated with depends, among other factors, on the quality and density of the observational coverage, on the precision and accuracy of the transport model used by the inversion to relat
Plant transpiration links physiological responses of vegetation to water supply and demand with hydrological, energy, and carbon budgets at the land-atmosphere interface. However, despite being the main land evaporative flux at the global scale, transpiration and its response to environmental drivers are currently not well constrained by observations. Here we introduce the first global compilation
The forest floor provides an important interface of soil-atmosphere CO2 exchanges but their controls and contributions to the ecosystem-scale carbon budget are uncertain due to measurement limitations. In this study, we deployed eddy covariance systems below- and above-canopy to measure the spatially integrated net forest floor CO2 exchange (NFFE) and the entire net ecosystem CO2 exchange (NEE) at
Peak bone mass is normally reached in the third decade of life. Previously, in the population-based PEAK-25 cohort (n = 1061, age 25.5 ± 0.2), we demonstrated that bone mineral density in the population-based PEAK-25 cohort is comparatively high; therefore, this study aimed to determine if the calcaneus microarchitecture mirrored this. In the process, we describe normative quantitative ultrasound
Methane emissions on the national scale in France in 2012 are inferred by assimilating continuous atmospheric mixing ratio measurements from nine stations of the European network ICOS located in France and surrounding countries. To assess the robustness of the fluxes deduced by our inversion system based on an objectified quantification of uncertainties, two complementary inversion set-ups are com
Sustainable development at the local level is greatly impacted by policymaking. In China’s Jingmai Mountain region, the sustainable development policies are centred mostly around the tea industry, due to the social and environmental dynamics surrounding tea in that region. However, considering the complex interlinkages between the tea industry and local environment and society, the policies concer
Traumatic brain injury (TBI) is a common cause of morbidity and mortality in young individuals. Following TBI, the initial injury caused by the head impact is exacerbated by a complex cascade of secondary injury factors leading to increased tissue loss. TBI is an established risk factor for neurodegenerative disorders including Alzheimer disease (AD). In long-term survivors of TBI, increased aggre
Galectins are an old fifteen-member protein family. Every galectin has one or two highly conserved carbohydrate recognition domains (CRDs) through which it binds their mutual ligand galactose. They are involved in various pathways such as signaling, autophagy and immune response. However, they also contribute to pathological functions including fibrosis, metastasis, cardiovascular diseases and dia
Från år 2021 ska alla nybyggnationer i Europa vara nära-nollenergibyggnader. Detta innebär att byggnaders energianvändning bör vara låg och i mycket hög grad tillförs i form från förnybara energikällor som produceras på plats eller i närheten. Syftet med de höga energikraven är att påskynda takten för att skapa ett mer energieffektivt byggande. Den minskade energianvändningen tillsam-mans med en ö
In recent years, low-cost flights to smaller cities in Central and Eastern Europe grew fast. This growth offered tourists new possibilities to explore new, lesser-known destinations at a low price. At the same time, urban tourism is a common strategy for urban regeneration and development in Central and Eastern Europe, and therefore, a significant factor of the economic restructuring of Post-Socia
The world today stands at a cross roads when it comes to energy and electrical grids. A large part of the worlds population still lacks access to reliable working electricity 24 hours a day. Much of this is in remote and poor parts of the world. For much of the 20th century large centralized AC grids have been the norm to provide people with electricity. But for remote parts of the world including
With millions of yearly beach visitors in southern California, beach water quality represents an important factor in public health and ocean dependent economy. Fecal indicator bacteria (FIB) in water is much easier to measure than disease causing organisms but correlation exists between the two. For this reason, FIB concentrations are used to measure recreational water quality and related health r
This work aimed to characterize single chain fragment variables (scFvs) against S100A7 and Calprotectin, proteins part of the Ca2+ binding S100 family that have been associated with inflammatory diseases and cancer. The mechanisms governing the physiological functions of S100 proteins are not fully understood, but it is known that many of them contribute to maintaining homeostasis in the intracell
