Search results

Critics maintain that there are a number of troublesome issues resulting from the construction sector’s way of operating and that these remain, despite widespread criticism and measures designed to change all of this. The construction sector’s and the critics’ manner of describing these problems fails to a large extent to take into consideration the way people function in connection with practical

Popular Abstract in Swedish Hemofili A är en form av blödarsjuka som beror på en medfödd defekt av äggviteämnet faktor VIII (FVIII). FVIII spelar en viktig roll för att kroppens blodlevringsförmåga (s.k. koagulation) ska fungera optimalt och med nedsatt funktion hos FVIII riskerar man att drabbas av allvarliga blödningar i framför allt leder, men även i muskler, slemhinnor (t.ex. näsblödning) och

Interactions between metals and natural organic matter (NOM) are of great environmental importance and one of the key factors influencing hydrolysis, solubility, and speciation of the metals. However, studying geochemically relevant metals like Al, Fe, and Cu is sometimes associated with analytical problems; for example Fe and Cu are both redox active. Gallium (Ga) is a non-redox active metal that

Background The leucine-rich repeat kinase 2 gene (LRRK2) harbours highly penetrant mutations that are linked to familial parkinsonism. However, the extent of its polymorphic variability in relation to risk of Parkinson's disease (PD) has not been assessed systematically. We therefore assessed the frequency of LRRK2 exonic variants in individuals with and without PD, to investigate the role of the

Background Immunotherapy targeting the amyloid beta (A beta) peptide is a potential strategy to slow the progression of Alzheimer's disease. We aimed to assess the safety and tolerability of CAD106, a novel active A beta immunotherapy for patients with Alzheimer's disease, designed to induce N-terminal A beta-specific antibodies without an A beta-specific T-cell response. Methods We did a phase 1,

In this work conformational studies have been performed on peptides from four different systems in an attempt to gain knowledge about their biological function. Circular dichroism (CD) spectroscopy and nuclear magnetic resonance (NMR) spectroscopy in combination with distance geometry and restrained molecular dynamics simulations were the methods used. A detailed conformational study of a cyclic p

Several beneficial effects have been connected with dietary fibre. Insoluble fibre has a good faecal bulking capacity, whereas soluble and viscous dietary fibre has been shown to have beneficial effects on carbohydrate and lipid metabolism. Fruit and vegetables provide about one third of the dietary fibre intake in Northern Europe and more than half in Mediterranean countries. These food items are

Popular Abstract in English Lions (Panthera leo) have become known to be synonymous with wild Africa since its extinction from most parts of its former range (Europe, Asia and Southern America). Few people realize that anthropogenic activities have caused habitat loss, fragmentation and reduction in size to the lions, forcing them to the brink of extinction. Whenever out in nature, most tourists tHigh growth rate in human populations, agricultural developments and industrialization have impinged negatively on the natural habitats of most large carnivores, causing fragmentation, isolation and consequently reduction in population size. Lions (Panthera leo) that once roamed most parts of Southern Europe, Asia, the Middle East, North America, northern part of South America and most parts of Af

The small heat shock proteins (sHsps) are a widespread class of molecular chaperones existing in all organisms. During heat stress the sHsps protect other proteins from unfolding and aggregation. In plants the sHsps play an especially prominent part of the stress response. In this thesis chemical crosslinking and mass spectrometric mapping of crosslinked peptides has been used to investigate the

This thesis investigates the adsorption, decomposition and reactions of small molecules on flat, oxidised and vicinal surfaces of late transition metals. The main technique for these studies is high resolution core level spectroscopy (HRCLS). All the studies presented in the thesis are performed in Ultra High Vacuum (UHV). The articles can be divided into three groups. The first three articles dea

Construction in rock is associated with risks because knowledge of the geology and ground conditions is limited. Unforeseen rock conditions involve a large risk to the project and can in the end entail delays and extra costs. To minimize the risks, an optimized pre-investigation program has to be conducted where essential information is gathered in order to make the best decisions throughout the c

Load problems in electricity markets occur both on the supply and demand side and can have technical, economic and even political causes. Commonly, such problems have been solved by expanding production and/or distribution capacity, importing electricity or by load management. Load management is a techno-economic measure for harmonizing the relations between supply and demand sides, optimizing pow

Popular Abstract in Swedish Många fåglar flyttar regelbundet långa sträckor mellan sina häckningsplatser och vinterkvarter. På rastningsplatser längs flyttningsvägen stannar fåglarna upp och äter, för att lagra upp de energi-lager de behöver som bränsle när de flyger. Vissa flyttfåglar lägger på sig så mycket bränsle (energi), mestadels som fett, att de dubblar sin kroppsvikt. Det lagrade bränslet

Popular Abstract in Swedish Hur gick det till när det svenska riket expanderade norrut och införlivade Hälsingland? Denna bok är uppställd som en generalhypotes över denna långt utdragna process, som tar sin utgångspunkt i den samhälleliga kollaps som är skönjbar under 500-talet. De inhemska maktstrukturer som gradvis byggdes upp efteråt kom under medeltidens inledande århundraden att få känna på In which way did the power structures of central Sweden expand into the territories north of the forest Ödmården during the Middle Ages? This text reads like a general hypothesis for this process, which attempts to incorporate all relevant elements in the Medieval landscape of power. The study area chosen is the province of Hälsingland. The chronological take-off is the 6th century AD, when settle

Stora Enso Nymölla is a pulp and paper mill mainly producing office paper. Their most well-known product is the MultiCopy paper. Every fourth year all large companies are by law required to present an energy audit. This can be done as one large report or by presenting smaller reports during the four-year period. Nymölla Mill has decided to publish short overviewing reports every year and combining

The fact that solitary migratory birds can find their migration routes has indicated the possibility that a genetic basis may be involved in determining the route of migration. Researchers have also found evidence to investigate this hypothesis in various ways. The focal species of this study is the willow warbler (Phylloscopus trochilus), which has three described subspecies (trochilus, acredula

This master’s thesis focuses on pedagogy and aspects of learning and remembering within guided museum tours for people with dementia. We explore in what way learning and remembering are focused on and triggered during those tours and with the help of which pedagogical means. Furthermore, we discuss what place these tours have within the museum as an institution. In order to examine our questions a

The product price given when producing offshore is not the entire truth and more companies decide to move their offshore production nearshore (Stentoft et. al, 2016). To measure the actual cost of producing many more parameters than visible costs needs to be taken account for. There are advantages as well as risks with outsourcing and costs can increase with distance such as quality issues, freigh