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Wnt-5a Signalling in Human Mammary Cells: Implications for the Development of Breast Cancer

The Wnt-5a gene encodes a secreted protein that regulates several normal processes in embryonic and adult tissues by as yet unknown mechanisms. Expression of Wnt-5a protein does not cause cell transformation, but it instead counteracts the effects induced by transforming Wnts. Inasmuch as Wnt-5a can activate the Wnt/beta-catenin signalling pathway, we performed experiments to determine whether mol

Capillary and interstitial transport of fluid and solutes across the peritoneal membrane

Popular Abstract in Swedish Vid njursvikt finns två huvudsakliga metoder för att rena blodet: bukdialys och bloddialys. Vid bukdialys, peritonealdialys (PD), används bukhinnan som dialysmembran, och sockerhaltig dialysvätska fylls på via en kateter i bukväggen. Under dialysen sker transport av slaggprodukter och överskottsvätska från blodet till bukhålan. Dialysen pågår kontinuerligt under hela dyAccording to the three-pore model of peritoneal transport the major exchange pathway between the blood and the peritoneal cavity is represented by “small pores”, permeable to small solutes and water. Osmotically induced fluid flow, as during peritoneal dialysis (PD), is postulated to occur to a great extent through a water-only pathway, whereas proteins are predicted to reach the peritoneal cavity

Phosphatidylethanol - formation and degradation in blood and organs.

Popular Abstract in Swedish Arbetet med denna avhandling har handlat om en abnormal fosfolipid (fettämne) som bildas i kroppens celler endast när alkohol är närvarande, lipiden kallas fosfatidyletanol (PEth). För att lättare kunna förstå resultaten av våra undersökningar börjar jag med en kort bakgrund. Alla kroppens celler är omgärdade av ett membran som skiljer dem från varandra och omgivningen.Phosphatidylethanol (PEth) is an abnormal phospholipid formed exclusively by the action of phospholipase D (PLD) in the presence of ethanol. The degradation of PEth is slow and due to its accumulation in some cells the possibility to use PEth as marker of ethanol intake has been proposed. It has also been suggested that PEth mediates some of the damaging effects of ethanol on cells. This study was

Psychotropic Pharmaceuticals in Aquatic Systems: An Ecological Perspective

Popular Abstract in English Psychotropic pharmaceuticals include various groups of chemicals that have been designed to affect neurochemistry in human consumers resulting in changes in cognition, mood, and/or behavior; many target specific receptors and subsequently alter neurotransmitter levels in the central nervous system. The use of pharmaceuticals by consumers results in the release of these Psychotropic pharmaceuticals have been shown to exert a variety of sublethal effects on non-target organisms, even at low concentrations found in the environment (ng/L to µg/L); hence, the aim of my research has been to determine the individual-level effects of psychotropic pharmaceuticals (the selective serotonin reuptake inhibitors sertraline and fluoxetine, and the β-blocker propranolol) on beh

Hushållsel-Energieffektivisering i vardagen

Tre funktionsområden i vardagslivet har analyserats grundligt nämligen Hel och ren, Mätt och belåten samt Underhållning och information. Användningen av hushållsel har ökat från 9,2 med cirka 10 TWh under en tidsperiod på drygt tre decennier. Ökningen förklaras bland annat av att antalet hushåll har ökat, men även av att innehavet av apparater ökat i hushållen. Dessutom har användningsmönster kr

The quality control of MHC class I antigen presentation

Popular Abstract in Swedish Ett antal olika behandlingsformer finns att tillgå vid angrepp av mikroorgansimer, tex antibiotika, samt vid uppkomsten av tumörer, tex strålbehandling och cellgifter. Ett alternativ till dessa traditionella behandlingssätt är att hjälpa kroppens immunförsvar att starta en specifik immunreaktion riktad mot de infekterade cellerna eller mot tumörcellerna. Detta vore en iMajor histocompatibility complex (MHC) class I molecules present antigenic peptides to CD8+ T cells. The peptides are generated by proteasomes in the cytosol, then translocated across the membrane of the endoplasmic reticulum (ER) by the transporter associated with antigen processing (TAP). Only properly assembled class I molecules loaded with high affinity peptides reach the cell surface. The mat

Nano- and Micro-sized Molecularly Imprinted Polymer Particles on Solid Surfaces

Popular Abstract in English Nanoscience and nanotechnology have existed in this world before scientists actually coined the terms. Nature around us and human beings themselves are all made of nanomaterials (1-100 nm), such as DNA, proteins, liposomes, and enzymes. These building blocks possess molecular recognition properties, resulting in their self-assembly to form various two- and three-dimensiMolecularly imprinted polymers (MIPs) are artificial receptors made by imprinting template molecules in a polymer matrix followed by their removal through washing to obtain a specific and selective template cavities. This property of the MIPs have made them a very efficient material for diverse applications such as chromatography, purification, drug sensing, etc. Recently, zero-dimensional polymer

Small biotopes: Landscape and management effects on pollinators

The intensification of agriculture during the second half of the twentieth century, has caused sever declines of farmland biodiversity, where loss of semi-natural habitats is one of the major drivers. To halt further loss of habitat and biodiversity, agri-environmental schemes (AES) are used to compensate farmers to use methods less harmful to the environment. In this thesis, I have investigated t

Defence and signalling in Potato-Phytophthora infestans interactions

Popular Abstract in English Plants harvest sunlight to fix air carbon dioxide into a form which is the fundamental source of energy for other organisms such as animals. The domestication of crop plants and traditional breeding practices has resulted in increased yield and nutritional value of crops. This comes at a cost of loss in genetic variability that is required by living organisms to adapt tPotato is one of the major food crops and its yield is severely affected by late blight disease caused by Phytophthora infestans. P. infestans has the ability to manipulate plant defence signalling by secreting effector molecules causing so called effector triggered susceptibility. Some plants can recognize these effectors via resistance proteins that reactivate plant defence and lead to effector

Global Proteome Survey -Transforming antibody-based affinity proteomics into a global discovery platform

Popular Abstract in Swedish En av de stora vetenskapliga bedrifterna hittills under 2000-talet är onekligen att man efter många års arbete för första gången lyckades kartlägga (sekvensera) samtliga mänskliga gener. Det mänskliga DNA:t är lokaliserat till cellkärnan och i princip så kan man likna en cellkärna med ett kontrollrum fyllt av manualer (DNA) som talar om cellens sammansättning och hur deProteomics is expected to generate new insights into biological processes as well as identify novel biomarkers and therapeutic targets since most biological functions are transmitted through proteins. However, due to the complexity displayed by a proteome and inherent limitations associated with current methodologies, proteomic analyses often result in incomplete coverage and inconsistent measurem

On Supply Chain Incentive Alignment: Insights from a cash supply chain and a trucking service supply chain

This dissertation presents a framework for describing, a process for identifying, and a model for evaluating misalignments in the supply chain when varying elements such as structure, processes, and management components. The developed approach makes it possible to address and improve the alignment of supply chain structures, processes, and management components. To further increase knowledge of h

Microfluidics Separation and Analysis of Biological Particles

In the last decade, powerful communication and information technology in the form of the mobile phone has been put into the hands of more than 50% of the global population. In stark contrast, a lack of access to medical diagnostic technology with which to diagnose both communicable and non-communicable diseases will mean that many of these people will die of easily treatable conditions. Small, por

Revealing movements of a willow warbler hybrid zone and the discovery of a new migratory divide

Ökning i sydliga lövsångares flyttningsbeteende Fåglars flyttning har länge fascinerat människan och kanske framförallt småfåglars flyttning. Hur kan t. ex. en lövsångare, Phylloscopus trochilus, på 10 gram som föddes för några månader sedan hitta hela vägen ner till övervintringsområdena i Afrika, dessutom helt utan hjälp av andra? Sedan länge är det känt att svaret verkar ligga i deras gener mDifferences in migratory behaviour has long been suggested to potentially drive speciation, but the genetics underlying this process remains a mystery. Studies of hybrid zones between two closely related taxa with contrasting migratory phenotypes, called migratory divides, have played a crucial role for our understanding of how such differences can lead to reproductive isolation. Movements of hybr

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Bästa resultat får du om du öppnar den här PDF-portföljen i Acrobat X eller Adobe Reader X eller senare. Hämta Adobe Reader nu! http://www.adobe.com/go/reader_download_se Kommunikation i teknisk utbildning Projektrapport för kommunikationsmoment i ESSF05 Mikael Evander och Andreas Lenshof, Biomedicinsk teknik Bakgrund ESSF05 – elektronikprojekt och hållbar utveckling är en av den sista obligatoris

https://www.lth.se/fileadmin/lth/genombrottet/KomTU-portfo__lj.pdf - 2026-05-29

Planktfbv018full 0

untitled HORIZONS Toward an ecologically meaningful view of resource stoichiometry in DOM-dominated aquatic systems MARTIN BERGGREN1*, RYAN A. SPONSELLER2, ANA R. ALVES SOARES1 AND ANN-KRISTIN BERGSTRÖM2 1 DEPARTMENT OF PHYSICAL GEOGRAPHY AND ECOSYSTEM SCIENCE, LUND UNIVERSITY, SE-223 62 LUND, SWEDEN AND 2 DEPARTMENT OF ECOLOGY AND ENVIRONMENTAL SCIENCE, UMEÅ UNIVERSITY, SE-901 87 UMEÅ, SWEDEN

https://www.nateko.lu.se/sites/nateko.lu.se/files/planktfbv018full_0.pdf - 2026-05-29

Strategisk plan för biologiska institutionen

Sammanställd av Jessica Abbott Här är webbversionen av vår strategiska plan. Planen gäller för åren 2022 till 2027. Under varje rubrik (förutom under inledningen) finns underrubrikerna Strategiska mål, Åtgärder 0–2 år, Åtgärder 3–5 år och Uppföljningsansvarig för att du lätt ska kunna få en överblick. Behöver du ha vår strategiska plan i pdf-format kontakta Joakim Nilsson (Joakim [dot] NIlsson [at

https://www.biologi.lu.se/internt/organisation-och-kontakt/strategisk-plan-biologiska-institutionen - 2026-05-27

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Långtidscovid | Spåra smittor | Lyckat sprutbyte LEVA MED H IV VANL IG FÖRKYLNING VÄDRA UT V IRUS När världen p o p u l ä r v e t e n s k a p l i g t o m f o r s k n i n g i n o m m e d i c i n o c h h ä l s a H Ö S T E N 2 0 2 2 & blir viral – om virus och pandemier Kan bli livsfarlig för vissa Bra ventilation viktig Vi är inte vår sjukdom 3 Vetenskap & hälsa ges ut av Medicinska fakulteten vid L

https://www.vetenskaphalsa.se/wp-content/uploads/2022/11/Vetenskap-o-halsa-hosten-2022.pdf - 2026-05-28

Microsoft Word - rapport 20080215.doc

Microsoft Word - rapport 20080215.doc Master’s Dissertation Structural Mechanics JOHAN DAHLBERG och JOHAN HEDLUND GRUNDFÖRSTÄRKNING MED STENPELARE Introduktion och beräkningsmodell Copyright © 2008 by Structural Mechanics, LTH, Sweden. Printed by KFS I Lund AB, Lund, Sweden, March, 2008. For information, address: Division of Structural Mechanics, LTH, Lund University, Box 118, SE-221 00 Lund, Swed

https://www.byggmek.lth.se/fileadmin/byggnadsmekanik/publications/tvsm5000/web5156.pdf - 2026-05-28

Tommy Shih

Universitetslektor Kontaktinformation E-post: tommy [dot] shih [at] fek [dot] lu [dot] seOrganisation Marknadsföring Hämtställe: 10 WebbplatsTommy Shihs profil i Lunds universitets forskningsportalAndra roller Docent Marknadsföring Publikationer Visar av publikationer. Sorterade efter år och sen titel. Filtrera efter typ AllaArtikel i tidskriftArtikel i uppslagsverkBokDel av eller Kapitel i bokKon

https://www.ehl.lu.se/tommy-shih - 2026-05-28