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Corticotropin-induced reduction of plasma lipoprotein(a) concentrations in healthy individuals and hemodialysis patients: relation to apolipoprotein(a) size polymorphism

Lipoprotein(a) [Lp(a)], a strong independent cardiovascular risk factor, consists of the unique apolipoprotein(a) [apo(a)] covalently linked to a low-density lipoprotein particle. Apo(a) contains a widely differing number of the plasminogen-like kringle IV, a size polymorphism that is codominantly inherited. In addition to powerful genetic control, renal failure is known to influence the plasma Lp

A regulatory polymorphism in PDCD1 is associated with susceptibility to systemic lupus erythematosus in humans

Systemic lupus erythematosus (SLE, OMIM 152700) is a complex autoimmune disease that affects 0.05% of the Western population, predominantly women(1-4). A number of susceptibility loci for SLE have been suggested in different populations, but the nature of the susceptibility genes and mutations is yet to be identified(5-9). We previously reported a susceptibility locus (SLEB2) for Nordic multi-case

Validation of the thermophysiological model by Fiala for prediction of local skin temperatures

The most complete and realistic physiological data are derived from direct measurements during human experiments; however, they present some limitations such as ethical concerns, time and cost burden. Thermophysiological models are able to predict human thermal response in a wide range of environmental conditions, but their use is limited due to lack of validation. The aim of this work was to vali

Top-down estimates of European CH4 and N2O emissions based on four different inverse models

European CH4 and N2O emissions are estimated for 2006 and 2007 using four independent inverse modelling systems, based on different global and regional Eulerian and Lagrangian transport models. This ensemble approach is designed to provide more realistic estimates of the overall uncertainties in the derived emissions, which is particularly important for verifying bottom-up emission inventories. We

Reduction Potentials and Acidity Constants of Mn Superoxide Dismutase Calculated by QM/MM Free-Energy Methods.

We used two theoretical methods to estimate reduction potentials and acidity constants in Mn superoxide dismutase (MnSOD), namely combined quantum mechanical and molecular mechanics (QM/MM) thermodynamic cycle perturbation (QTCP) and the QM/MM-PBSA approach. In the latter, QM/MM energies are combined with continuum solvation energies calculated by solving the Poisson-Boltzmann equation (PB) or by

Effect of food intake on left and right ventricular systolic tissue Doppler measurements.

Systolic tissue Doppler measurements (s') have been used to measure the velocity in myocardial motion and are a valuable tool for evaluating the systolic function of the left and right ventricles. Digestion of food is known to significantly alter hemodynamics and may therefore affect s'. The effect of food intake on s' parameters has not yet been studied. We assessed whether s' is affected by food

Interact or counteract? Behavioural observation of interactions between vulnerable road users and autonomous shuttles in Oslo, Norway

The current paper presents the results of behavioural observations in a field experiment with automated shuttles in Oslo, Norway. Video observations were conducted at five fixed locations along a challenging 1.2 km automated shuttle line with varying traffic conditions. Observed interactions between vulnerable road users and automated shuttles were coded using a predefined codebook, which allowed

The Impact of Stimulation Parameters on Reaction Times Following Transcutaneous Electrical Stimulation in the Lower Leg

The growing need for human-machine interfaces (HMIs) underscores the importance of sensory feedback, with electrical stimulation offering efficient interaction in various applications. While its sensory effects are extensively studied, investigations into the reaction time (RT) following transcutaneous electrical stimulation (TES) remain limited. This study aimed to evaluate how stimulation parame

Masterrapport till gul

Först ut En alumnstudie av de första årskullarna från de nya magister- /masterutbildningarna vid Lunds och Uppsala universitet Maria Björnermark, Camilla Maandi och Hanne Smidt september 2014 Förord Vi vill rikta ett stort tack till de alumner som möjliggjort denna studie genom att besvara den enkät som skickats ut. Vi tackar även projektets styrgrupp som utgjorts av Katarina Borne vid Göteborgs u

https://www.lu.se/sites/www.lu.se/files/masterrapport_till_gul.pdf - 2026-06-08

Recent past (1979-2014) and future (2070-2099) isoprene fluxes over Europe simulated with the MEGAN-MOHYCAN model

Isoprene is a highly reactive volatile organic compound emitted by vegetation, known to be a precursor of secondary organic aerosols and to enhance tropospheric ozone formation under polluted conditions. Isoprene emissions respond strongly to changes in meteorological parameters such as temperature and solar radiation. In addition, the increasing CO2 concentration has a dual effect, as it causes b

Analgesic antipyretic use among young children in the TEDDY study : No association with islet autoimmunity

Background: The use of analgesic antipyretics (ANAP) in children have long been a matter of controversy. Data on their practical use on an individual level has, however, been scarce. There are indications of possible effects on glucose homeostasis and immune function related to the use of ANAP. The aim of this study was to analyze patterns of analgesic antipyretic use across the clinical centers o

General Study Plan Medical Science, Doctoral Degree (1)

Microsoft Word - General study plan_Medical Science, doctoral degree.doc Research Studies Board GENERAL STUDY PLAN FOR DOCTORAL STUDIES IN MEDICAL SCIENCE Scope: 240 credits Qualification: Degree of Doctor Details of approval: Approved by the Research Studies Board on 11 June 2018 Applies from: 1 January 2019 Amended: 10 December 2018 This is a translation of the Swedish version. In the event of a

https://www.intramed.lu.se/en/sites/intramed.lu.se.en/files/2023-06/General%20study%20plan_Medical%20Science,%20doctoral%20degree%20(1).pdf - 2026-06-08

125 MP120a Johnson Diabetologia 2021

First-appearing islet autoantibodies for type 1 diabetes in young children: maternal life events during pregnancy and the child’s genetic risk ARTICLE First-appearing islet autoantibodies for type 1 diabetes in young children: maternal life events during pregnancy and the child’s genetic risk Suzanne Bennett Johnson1 & Kristian F. Lynch2 & Roswith Roth3 & Markus Lundgren4 & Hemang M. Parikh2 & Bee

https://www.teddy.lu.se/sites/teddy.lu.se/files/2021-11/125_MP120a_Johnson_Diabetologia_2021.pdf - 2026-06-08

3D printing with moondust

Purpose - The purpose of this paper is to investigate the effect of the main process parameters of laser melting (LM) type additive manufacturing (AM) on multi-layered structures manufactured from JSC-1A Lunar regolith (Moondust) simulant powder. Design/methodology/approach - Laser diffraction technology was used to analyse and confirm the simulant powder material particle sizes and distribution.

The Weichselian in southern Sweden and southwestern Baltic Sea : glacial stratigraphy, palaeoenvironments and deglaciation chronology

Popular Abstract in Swedish Genom att studera forna inlandsisar kan vi få en inblick i hur en inlandsis påverkar och påverkas av till exempel klimatförändringar och havsnivåvariationer i tidsperspektiv från hundratals till hundratusentals år. I Skandinavien är det framförallt spåren efter nedisningar under den senaste istiden, Weichsel-istiden, som bevarats. I den här studien fokuserar vi på ÖstIn this thesis the Weichselian glaciation history of southernmost Sweden and the southwestern Baltic Basin is discussed, with special emphasis on Middle and Late Weichselian ice advances and subsequent deglaciations. The main study area was Kriegers Flak in the southwestern Baltic Sea where pre-Late Weichselian sediments were identified. We suggest that the lowermost till on Kriegers Flak, dated t