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Introduction. Perioperative chemotherapy is the standard treatment for patients with locally advanced resectable gastric cancer. The prognostic relevance of MSI status in patients undergoing neoadjuvant chemotherapy remains unclear. Aim. To study the prognostic significance of MSI in gastric cancer patients undergoing perioperative CT. Materials and methods. The study included 173 patients with lo
Xylosides are a group of compounds that can induce glycosaminoglycan (GAG) chain synthesis independently of a proteoglycan core protein. We have previously shown that the xyloside 2-(6-hydroxynaphthyl)β-D-xylopyranoside has a tumor-selective growth inhibitory effect both in vitro and in vivo, and that the effect in vitro was correlated to a reduction in histone H3 acetylation. In addition, GAG cha
The prognostic impact of t(12;21)(p13;q22) [ETV6/RUNX1 fusion] in paediatric acute lymphoblastic leukaemia (ALL) has been extensively debated, particularly with regard to the frequency of late relapses and appropriate treatment regimens. We have retrospectively collected 679 ALLs with known ETV6/RUNX1 status, as ascertained by fluorescence in situ hybridization or reverse-transcription polymerase
The Italian Sarcoma Group and the Scandinavian Sarcoma Group designed a joint study to improve the prognosis for patients with Ewing's family tumors and synchronous metastatic disease limited to the lungs, or the pleura, or a single bone. The study was opened in 1999 and closed to the enrollment in 2008. The program consisted of intensive five-drug combination chemotherapy, surgery and/or radiothe
The objectives of the present study were to estimate 10-year probabilities of clinical vertebral fractures in women, according to age and bone mineral assessment using phalangeal quantitative ultrasound (QUS). Risks were computed from UK derived data on the incidence of a first symptomatic vertebral fracture and mortality rates for each year of age using Poisson models. The 10-year probability of
DNA copy number aberrations (CNAs) are a hallmark of cancer genomes. However, little is known about how such changes affect global gene expression. We develop a modeling framework, EPoC (Endogenous Perturbation analysis of Cancer), to (1) detect disease-driving CNAs and their effect on target mRNA expression, and to (2) stratify cancer patients into long-and short-term survivors. Our method constr
Increased serum concentrations of the beta subunit of human chorionic gonadotropin (hCG beta) are associated with adverse prognosis in several cancers. The aim of the present study was to analyse the association between serum hCG beta recurrence, and survival, in patients with colorectal cancer. The concentrations of hCG beta were determined in serum collected preoperatively from 324 patients with
Catalytic metal sites in enzymes frequently have second-sphere carboxylate groups that neutralize the charge of the site and share protons with first-sphere ligands. This gives rise to an ambiguity concerning the position of this proton, which has turned out to be hard to settle with experimental, as well as theoretical, methods. We study three such proton-transfer reactions in two proteins and sh
In bottom-up mass spectrometry (MS)-based proteomics, peptide isotopic and chromatographic traces (features) are frequently used for label-free quantification in data-dependent acquisition MS but can also be used for the improved identification of chimeric spectra or sample complexity characterization. Feature detection is difficult because of the high complexity of MS proteomics data from biologi
alpha(1)-Microglobulin is a 26-kDa glycoprotein synthesized in the liver, secreted to the blood, and rapidly distributed to the extravascular compartment of all tissues. Recent results show that alpha(1)-microglobulin has heme-binding and heme-degrading properties and it has been suggested that the protein is involved in the defense against oxidation by heme and reactive oxygen species. In the pre
Ansträngningsutlöst andningsfunktionsstörning drabbar främst barn och ungdomar, oftast i samband med idrottsutövning och är vanligare bland flickor än pojkar. Mekanismerna bakom besvären är komplexa och inte helt klarlagda. Enhetliga rutiner för omhändertagandet finns inte. Syftet med uppsatsen var att kartlägga och utvärdera omhändertagandet av personer med dessa besvär vid Röst- och TalvårdsavdeExercise-induced respiratory dysfunction affects mostly children and young people, usually during athletic performance, and is more common among girls than boys. The mechanisms of the disorder are complex and not fully understood. Uniform clinical procedures for examination and treatment of these patients are not established. The purpose of this paper was to identify and evaluate the present care
27-hydroxycholesterol (27HC), synthesized from cholesterol by the enzyme CYP27A1, differentially impacts estrogen receptor positive (ER+) breast cancer (BC) cell growth depending on estrogen levels. This study examined the association between CYP27A1 expression and prognosis in a cohort of 193 premenopausal patients with lymph node-negative primary BC with limited exposure to adjuvant systemic can
IT IS NOW TIME TO COMPLETE THE RENOVATION OF OUR GYM AND MAKE SPACE FOR MORE FREE WEIGHT TRAINING - Gerdahallen MoreMenu_white Group 3 Our services Schedule/Book English Become a member Login MoreMenu_white Group 3 Our services Schedule/Book English Menu Offer Our facilities Lund Schedule/Book Corporation About us Contact Lund Lund The Foundation for Exercise Activities at Lund University Helgonav
Congratulations and welcome to the course STVB30! Welcome to the Political Science Department at Lund University. Please see the information below that you need to know in order to secure our offer. It is important that you read the information thoroughly. Secure your place – important deadline You must accept the offer no later than 20 July at 23:59 (Swedish time).If you do not accept the offer b
Congratulations and welcome to the course STVC76! Welcome to the Political Science Department at Lund University. Please see the information below that you need to know in order to secure our offer. It is important that you read the information thoroughly. Secure your place – important deadline You must accept the offer no later than 20 July at 23:59 (Swedish time).If you do not accept the offer b
https://www.svet.lu.se/en/education/new-student-admission-information/political-science-comparative-politics - 2026-05-13
Congratulations and welcome to the course STVC55! Welcome to the Political Science Department at Lund University. Please see the information below that you need to know in order to secure our offer. It is important that you read the information thoroughly. Secure your place – important deadline You must accept the offer no later than 20 July at 23:59 (Swedish time).If you do not accept the offer b
https://www.svet.lu.se/en/education/new-student-admission-information/political-science-environmental-governance - 2026-05-13
Welcome to the course STVN22 – Policy Processes: Actors, Causes and Consequences! We are pleased to welcome you to the Department of Political Science at Lund University. To secure your place on the course, please read the information below carefully. Secure your place – important deadline You must accept the offer no later than 20 July at 23:59 (Swedish time).If you do not accept the offer by thi
Congratulations and welcome to the course STVP30 We are pleased to welcome you to the Department of Political Science at Lund University. To secure your place on the course, please read the information below carefully. Secure your place – important deadline You must accept the offer no later than 20 July at 23:59 (Swedish time).If you do not accept the offer by this deadline, it will be withdrawn.
https://www.svet.lu.se/en/education/new-student-admission-information/political-science-european-governance - 2026-05-13
2016 Ahlgren A, Knutsson L, Wirestam R, Nilsson M, Ståhlberg F, Topgaard D, Lasič S. Quantification of microcirculatory parameters by joint analysis of flow-compensated and non-flow-compensated intravoxel incoherent motion (IVIM) data.NMR Biomed. 2016 May;29(5):640-9. Calamante F, Ahlgren A, van Osch MJ, Knutsson L.A novel approach to measure local cerebral haematocrit using MRI.J Cereb Blood Flow
https://www.msf.lu.se/research/mr-physics-group/publications/papers/2007-2016 - 2026-05-13
ClimBEco is a two-year graduate research school focused on Climate, Biodiversity and Ecosystem services. The school promotes interdisciplinary research by supporting PhD students in networking and learning across different fields of study. Is ClimBEco something for me?When you join the ClimBEco graduate research school, you will enter an inspiring research environment where you can:Meet and networ
https://www.mgeo.lu.se/en/research/research-schools/climbeco-graduate-research-school - 2026-05-13
