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alpha(1)-Microglobulin is a 26-kDa glycoprotein synthesized in the liver, secreted to the blood, and rapidly distributed to the extravascular compartment of all tissues. Recent results show that alpha(1)-microglobulin has heme-binding and heme-degrading properties and it has been suggested that the protein is involved in the defense against oxidation by heme and reactive oxygen species. In the pre
DNA copy number aberrations (CNAs) are a hallmark of cancer genomes. However, little is known about how such changes affect global gene expression. We develop a modeling framework, EPoC (Endogenous Perturbation analysis of Cancer), to (1) detect disease-driving CNAs and their effect on target mRNA expression, and to (2) stratify cancer patients into long-and short-term survivors. Our method constr
Popular Abstract in Swedish Bröstcancer är kvinnans vanligaste cancerform och globalt sett den cancer som leder till flest dödsfall. Bröstcancerscreening med mammografi används därför i syfte att hitta cancern tidigt. En tidigt upptäckt cancer har oftast en bättre prognos med möjlighet att minska dödligheten i bröstcancer. Mammografitekniken är dock behäftad med vissa begränsningar vad gäller känsAbstract: Mammography is currently the established method in breast cancer screening, although the sensitivity is known be affected by overlapping tissue concealing tumours. Breast tomosynthesis takes advantage of multiple exposures at different angles reducing the negative effect of obscuring tissue. The aim of this thesis was to investigate the use of tomosynthesis in breast imaging with a spec
The prognostic impact of t(12;21)(p13;q22) [ETV6/RUNX1 fusion] in paediatric acute lymphoblastic leukaemia (ALL) has been extensively debated, particularly with regard to the frequency of late relapses and appropriate treatment regimens. We have retrospectively collected 679 ALLs with known ETV6/RUNX1 status, as ascertained by fluorescence in situ hybridization or reverse-transcription polymerase
The objectives of the present study were to estimate 10-year probabilities of clinical vertebral fractures in women, according to age and bone mineral assessment using phalangeal quantitative ultrasound (QUS). Risks were computed from UK derived data on the incidence of a first symptomatic vertebral fracture and mortality rates for each year of age using Poisson models. The 10-year probability of
Catalytic metal sites in enzymes frequently have second-sphere carboxylate groups that neutralize the charge of the site and share protons with first-sphere ligands. This gives rise to an ambiguity concerning the position of this proton, which has turned out to be hard to settle with experimental, as well as theoretical, methods. We study three such proton-transfer reactions in two proteins and sh
We have studied the photoinduced low spin (LS) to high spin (HS) conversion of [Fe(bipy)(3)](2+) in aqueous solution. In a laser pump/X-ray probe synchrotron setup permitting simultaneous, time-resolved X-ray diffuse scattering (XDS) and X-ray spectroscopic measurements at a 3.26 MHz repetition rate, we observed the interplay between intramolecular dynamics and the intermolecular caging solvent re
The Italian Sarcoma Group and the Scandinavian Sarcoma Group designed a joint study to improve the prognosis for patients with Ewing's family tumors and synchronous metastatic disease limited to the lungs, or the pleura, or a single bone. The study was opened in 1999 and closed to the enrollment in 2008. The program consisted of intensive five-drug combination chemotherapy, surgery and/or radiothe
Introduction. Perioperative chemotherapy is the standard treatment for patients with locally advanced resectable gastric cancer. The prognostic relevance of MSI status in patients undergoing neoadjuvant chemotherapy remains unclear. Aim. To study the prognostic significance of MSI in gastric cancer patients undergoing perioperative CT. Materials and methods. The study included 173 patients with lo
27-hydroxycholesterol (27HC), synthesized from cholesterol by the enzyme CYP27A1, differentially impacts estrogen receptor positive (ER+) breast cancer (BC) cell growth depending on estrogen levels. This study examined the association between CYP27A1 expression and prognosis in a cohort of 193 premenopausal patients with lymph node-negative primary BC with limited exposure to adjuvant systemic can
There are hundreds of thousands of moth species with crucial ecological roles that are often obscured by their nocturnal lifestyles. The pigmentation and appearance of moths are dominated by cryptic diffuse shades of brown. In this study, 82 specimens representing 26 moth species were analysed using infrared polarimetric hyperspectral imaging in the range of 0.95–2.5 µm. Contrary to previous studi
Ansträngningsutlöst andningsfunktionsstörning drabbar främst barn och ungdomar, oftast i samband med idrottsutövning och är vanligare bland flickor än pojkar. Mekanismerna bakom besvären är komplexa och inte helt klarlagda. Enhetliga rutiner för omhändertagandet finns inte. Syftet med uppsatsen var att kartlägga och utvärdera omhändertagandet av personer med dessa besvär vid Röst- och TalvårdsavdeExercise-induced respiratory dysfunction affects mostly children and young people, usually during athletic performance, and is more common among girls than boys. The mechanisms of the disorder are complex and not fully understood. Uniform clinical procedures for examination and treatment of these patients are not established. The purpose of this paper was to identify and evaluate the present care
english | Department of Design Sciences Skip to main content This site uses cookies to enhance the user experience. By continuing to use the site you agree that cookies are used according to our Cookie Policy (on the website of LTH) . Essential cookies These cookies are necessary for the website to function and cannot be turned off in our systems. These cookies do not store any personally identifi
https://www.design.lth.se/english/ - 2026-07-25
Milan Design Week 2026 Skip to main content This site uses cookies to enhance the user experience. By continuing to use the site you agree that cookies are used according to our Cookie Policy (on the website of LTH) . Essential cookies These cookies are necessary for the website to function and cannot be turned off in our systems. These cookies do not store any personally identifiable information.
https://www.innovation.lth.se/article/milan-design-week-2026/ - 2026-07-25
Objective: To assess foetal circulating free foetal haemoglobin (fHbF) levels and heme defences, correlated to foetal circulatory biometry and foetal sex in severe early-onset foetal growth restriction (FGR). Design, Setting and Population: A prospective study severe early-onset foetal growth restriction pregnancies with close clinical management (estimated foetal weight (EFW) < 3rd centile and <
Kursplan för Ledning och samverkan över hela hotskalan Command and Collaboration in Crisis Response Management TFRU26, 5 högskolepoäng, A (Avancerad nivå) Gäller för: LTH:s uppdragsutbildningar Beslutad av: Programledning BI/RH Beslutsdatum: 2019-11-13 Allmänna uppgifter Undervisningsspråk: Kursen ges på svenska Syfte Syftet med kursen är att ge yrkesverksamma inom krisberedskap, civilt försvar oc
https://www.lu.se/sites/www.lu.se/files/officiell_kursplan_for_ledning_och_samverkan.pdf - 2026-07-25
Empowering student entrepreneurs Spark* Lund is a student-to-student coaching service at Lund University driven by active students from our Master's programme in Entrepreneurship and Innovation. It empowers the students to pursue their entrepreneurial ideas by providing guidance and support through the first steps of their journey. Spark* Lund exemplifies the Centre’s commitment to practical, hand
Congratulations and welcome to the course STVN24! Welcome to the Political Science Department at Lund University. Please see the information below that you need to know in order to secure our offer. It is important that you read the information thoroughly. Secure your place – important deadline You must accept the offer no later than 20 July at 23:59 (Swedish time).If you do not accept the offer b
https://www.svet.lu.se/en/education/new-student-admission-information/comparative-politics-institutions-and-actors - 2026-07-23
Don’t miss the opportunity to take our X-Courses for a chance to broaden your skills! Each course is worth 5 credits and is offered part-time, making it suitable to combine with your regular studies. The courses cover various current societal issues, allowing you to apply your knowledge in your studies, future career, and everyday life. There are only general entry requirements for the X-Courses,
https://www.law.lu.se/study/x-courses - 2026-07-23
