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The efficacy and safety of an advanced category recombinant antihaemophilic factor produced by a plasma- and albumin-free method (rAHF-PFM) was studied in 111 previously treated subjects with haemophilia A. The study comprised a randomized, double-blinded, crossover pharmacokinetic comparison of rAHF-PFM and RECOMBINATE rAHF (R-FVIII); prophylaxis (three to four times per week with 25-40 IU kg(-1)

For unknown reasons, there is a greater increase in the risk for cardiovascular complications in diabetic women than in diabetic men. Our aim was to study gender-related differences in the mechanical properties of the great arteries in patients with insulin-dependent diabetes mellitus (IDDM) but free from known cardiovascular and cerebrovascular complications. We measured arterial stiffness (beta,

The transcription factor SOX2 is a well-established and important stem cell marker. Its role in cancer biology remains unclear, but it has been proposed to also be a marker of cancer stem cells. We investigated the role of SOX2 protein expression in women with high-grade serous ovarian cancer (HGSOC) to determine its potential prognostic and treatment predictive value. We constructed a tissue micr

Purpose The purpose of this study was to estimate the uncertainty in voluntary deep-inspiration breath-hold (DIBH) radiotherapy for locally advanced non-small cell lung cancer (NSCLC) patients. Methods Perpendicular fluoroscopic movies were acquired in free breathing (FB) and DIBH during a course of visually guided DIBH radiotherapy of nine patients with NSCLC. Patients had liquid markers injected

In E. coli cells ribosomal small subunit biogenesis is regulated by RNA-protein interactions involving protein S7. S7 initiates the subunit assembly interacting with 16S rRNA. During shift-down of rRNA synthesis level, free S7 inhibits self-translation by interacting with 96 nucleotides long specific region of streptomycin (str) mRNA between cistrons S12 and S7 (intercistron). Many bacteria do not

Serum free light chain (FLC) concentration is greatly affected by kidney function. Using a large prospective population-based cohort, we aimed to establish a reference interval for FLCs in persons with chronic kidney disease (CKD). A total of 75422 participants of the iStopMM study were screened with serum FLC, serum protein electrophoresis and immunofixation. Estimated glomerular filtration rate

The morphology and function of the arteries can be directly measured using different established methods. This prospective cohort study aimed to translate 2 of these, aortic pulse wave velocity (aPWV) and carotid intima–media thickness (cIMT), into a combined Vascular Aging Index (VAI) and then evaluate the predictive power of aPWV, cIMT, and VAI. Patients (n = 2718) were included from the cardiov

There are hundreds of thousands of moth species with crucial ecological roles that are often obscured by their nocturnal lifestyles. The pigmentation and appearance of moths are dominated by cryptic diffuse shades of brown. In this study, 82 specimens representing 26 moth species were analysed using infrared polarimetric hyperspectral imaging in the range of 0.95–2.5 µm. Contrary to previous studi

The prognostic impact of PICALM::MLLT10 status in childhood leukaemia is not well described. Ten International Berlin Frankfurt Münster-affiliated study groups and the Children's Oncology Group collaborated in this multicentre retrospective study. The presence of the PICALM::MLLT10 fusion gene was confirmed by fluorescence in situ hybridization and/or RNA sequencing at participating sites. Ninety-

Adjungerad professor Kontaktinformation E-post: linda [dot] knutsson [at] med [dot] lu [dot] seOrganisation Medicinsk strålningsfysik, Lund Hämtställe: 32 WebbplatsLinda Knutssons profil i Lunds universitets forskningsportalAndra roller Projektledare MR Physics Profilområdesmedlem Lunds lasercentrum, LLC Profilområdesmedlem LTH profilområde: Avancerade ljuskällor Medlem i Strategiskt forskningsomr

https://www.msf.lu.se/linda-knutsson - 2026-05-14

This master’s thesis maps and compares local literary networks within UNESCO’s Cities of Literature, with the aim of understanding how such networks are structured, what their functions are and how they are controlled and developed. Drawing on concepts from social network analysis and Bourdieu’s theories of social fields, capital and habitus, the study combines quantitative and qualitative methods

The aim of this study was to test the hypothesis that gastric bacterial overgrowth is a side effect of acid suppression therapy in patients with gastroesophageal reflux disease (GERD) and that the bacteria-contaminated gastric milieu is responsible for an increased amount of deconjugated bile acids. Thirty patients with GERD who were treated with 40 mg of omeprazole for at least 3 months and 10 pa

As a promising carbon-free fuel, iron powder can directly combust with air and has great potential to provide clean and high-grad heat for various applications. The combustion characteristics of iron particles are of great significance for developing iron combustion model, designing efficient combustor, and optimizing combustion technologies. In this work, the micro-explosion behavior of burning i

Background: We evaluated the efficacy and safety of the aromatase inhibitor exemestane in patients with advanced, persistent or recurrent endometrial carcinoma. Methods: We performed an open-label one-arm, two-stage, phase II study of 25 mg of oral exemestane in 51 patients with advanced (FIGO stage III-IV) or relapsed endometrioid endometrial cancer. Patients were stratified into subsets of estro

Postal address Lunds universitet, Box 117, 221 00 Lund Visiting address Scheeletorget 1, Medicon Village Telephone 046-222 00 00 Email malin.bredenberg@fs.lu.se Website www.fs.lu.se Research Serv ices Lund University’s internal management rules for applications to the Knut and Alice Wallenberg Foundation – grants for research projects with high scientific potential. Application deadline 1 February

https://www.staff.lu.se/sites/staff.lu.se/files/2023-05/Management%20Rules%20LU%20KAW%20project%202024.pdf - 2026-05-15

Den svenska missbruks- och narkotikamodellen bygger på en restriktiv straffrättslig kontroll med ett narkotikafritt samhälle som mål. Trots detta har Sverige idag högst narkotikarelaterad dödlighet i Europa. Portugal använder istället en modell där skademinimering är centralt och förvärv och innehav avsett för eget bruk samt eget bruk är avkriminaliserat. I dagsläget verkar också Norge ta in på etThe Swedish drug control strategy is based on restrictive criminal law where the goal is a society free from illicit drugs. However, today Sweden has the highest drug-related mortality in Europe. Countries like Portugal use a different model where harm reduction is central and acquisitions, personal possession and consumption are decriminalized. Norway is also taking an interest in switching to a

Static anatomical and real-time dynamic magnetic resonance imaging (RT-MRI) of the upper airway is a valuable method for studying speech production in research and clinical settings. The test-retest repeatability of quantitative imaging biomarkers is an important parameter, since it limits the effect sizes and intragroup differences that can be studied. Therefore, this study aims to present a fram

Från romartida skalpeller till senvikingatida urnesspännen Nya materialstudier från Uppåkra REDAKTÖR: BIRGITTA HÅRDH UPPÅKRASTUDIER 11 ACTA ARCHAEOLOGICA LUNDENSIA SERIES IN 8°, No. 61 I den tryckta upplagan finns följande uppgifter: Omslagsbild: Spänne U2077. Foto: B. Almgren, LUHM © Institutionen för Arkeologi och Antikens Historia Grafisk form: Stilbildarna i Mölle/Frederic Täckström Tryck: Kri

https://www.uppakra.lu.se/fileadmin/_migrated/content_uploads/11._Fraan_romartida_skalpeller_till_senvikingatida_urnesspaennen_liten.pdf - 2026-05-14

The institution of energy consulting services is one of the several government instruments for improving the efficiency of energy usage in many European countries. Various forms of advice on energy issues are offered to households. In Sweden, there has been a drop in the number of households who avail of this service, even though it is offered independently, free of charge and easily accessible. I