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Male patients with terminal renal failure are often infertile and exhibit an abnormal sex hormone pattern in plasma. We studied patients in all chronic kidney disease (CKD) stages to determine plasma levels of anti-Müllerian hormone (AMH), a Sertoli cell-derived marker, and other sex hormones. Seventy-eight male patients with CKD stages 1-5 and a median age of 40 years (22-50 years), as well as 20

Popular Abstract in Swedish Under det senaste decenniet har risker med och alternativ till allogent blod (blod från främmande givare) debatterats mycket pga. risken för smitta, allergiska reaktioner, samt starka indicier som talar för att blod från främmande givare kan påverka immunförsvaret hos mottagaren. Därför vill man gärna begränsa mängden tillfört givarblod under kirurgiska ingrepp på barn,In children, it is often desirable to minimize allogenic blood transfusion, and this thesis explores the physiology of an alternative method of managing perioperative blood loss: hemodilution with Ringer´s dextran. Methods Clinical studies: Arterial pressure, superior caval venous oxygen saturation (ScvO2) and blood lactate concentration (L) were studied during bone marrow harvesting (BMH) on 23

Liquid-crystalline cubic-phase nanoparticles (CPNPs) (known as Cubosome particles), based on the lipid glycerol monooleate and stabilized by the nonionic block copolymer Pluronic F-127, interact with supported model membranes consisting of dioleoylphosphatidylcholine (DOPC) in a complex and dynamic fashion. Neutron reflectivity measurements on the interaction of CPNPs with bilayers of different co

Adult patients with acute lymphoblastic leukaemia ( ALL) have been treated according to national protocols in Sweden since 1986. Stem cell transplantation (SCT) has been recommended in first remission for patients with risk factors for relapse, and for standard risk patients only after relapse. In this retrospective study, the results of autologous and allogeneic SCT in these populations were eval

This paper investigates how the financial sector's institutional characteristics can allow an economy to benefit from financial deepening and limit the negative effects it can have. Specifically, it tests how macroprudential regulation and financial liberalisation affect the shape and behaviour of the finance–growth relationship. This is done by analysing a sample of 55 developing and develope

Context. To use the data in the future Gaia catalogue it is important to have accurate estimates of the statistical uncertainties and correlations of the errors in the astrometric data given in the catalogue. Aims. In a previous paper we derived a mathematical model for computing the covariances of the astrometric data based on series expansions and a simplified attitude description. The aim of th

Former research indicates that the crack width close to the bar can be a better indicator for the risk for reinforcement corrosion than, as current concrete codes impose, the crack width at the concrete surface. In this paper a finite-element model is used to increase the understanding of how the crack width varies at different levels from the reinforcement and how different mechanisms control thi

Initiation of construction of apartments has increased by 26% from 2014 to 2015 in Sweden. This has meant more building permits to treat. Several tasks done by a building inspector has been identified through active observation of the building permit department in Helsingborg. Some of the tasks are review of cases, technical consultation, and visits at building places, final consultation, supervis

The aim of this master thesis is to provide an indication of the suitability, or otherwise usage, of spray-drying for production of powder aimed for inhalation formulation and comparing the characteristics of the product, with and without lipids. Lipids have a proven effect of delaying release of active drug substances in the cardiovascular system and pulmonary systemic delivery has a number of ad

Uppsatsens syfte är att undersöka begreppet "brottslighetens art" i 30 kap. 4 § BrB. Brottslighetens art utgör ett skäl för att välja fängelse vid påföljdsvalet och är främst av vikt för att avgöra om fängelse ska väljas vid lägre straffvärden. Uppsatsen tillämpar en rättsdogmatisk metod för att undersöka den rättsliga innebörden av brottslighetens art och varför brottslighetens art inf

This thesis analyzes the corporate rebalancing behavior of German publicly listed firms subsequent to equity price shocks. The examined period (1990-2012) includes a total sample of 2,154 firm-years. It is found that German firms do not counteract stock induced changes in market-based capital ratios in the short run; whereas managerial rebalancing activity gradually gains importance in the long-te

Objective: Studies of the importance of perinatal factors for the development of irritable bowel syndrome (IBS) are sparse. We conducted a large national cohort study to examine perinatal and familial risk factors for IBS. Material and methods: A national cohort of 1,963,685 persons who were born in Sweden in 1973–1992 (identified from the Swedish Birth Registry) were followed up for adult (18 yea

Protein synthesis, measured as [14C]-leucine incorporation into proteins, was studied in the normothermic rat brain following 15 min of transient cerebral ischaemia and 1 h, 24 h and 48 h of recirculation, and in the hypothermic (33°C) brain following 1 h and 48 h of recirculation. Ischaemia was induced by bilateral common carotid occlusion combined with hypotension. Following normothermic ischaem

Background  Gastrostomy placement in children is one of the most frequently performed pediatric surgical procedures and laparoscopic-assisted gastrostomy (LAG) is the preferred technique. Wound infection after LAG has become a significant concern due to the emergence of antibiotic resistance. The aim of this study was to describe the frequency of wound infection after LAG in children younger than

Nemo-like kinase (NLK) is a member of the mitogen-activated protein kinase family of kinases and shares a highly conserved kinase domain with other mitogen-activated protein kinase family members. The activation of NLK contributes to the pathogenesis of Diamond–Blackfan anemia (DBA), reducing c-myb expression and mechanistic target of rapamycin activity, and is therefore a potential therapeutic ta

Background: The contribution of endothelial injury in the pathogenesis of COVID-19-associated acute respiratory distress syndrome (ARDS) and resulting respiratory failure remains unclear. Plasma endostatin, an endogenous inhibitor of angiogenesis and endothelial dysfunction is upregulated during hypoxia, inflammation and progress of pulmonary disease. Aim: To investigate if plasma endostatin is as

Objective: To assess the quality of maternal and newborn care (QMNC) in countries of the former Yugoslavia. Method: Women giving birth in a facility in Slovenia, Croatia, Serbia, and Bosnia-Herzegovina between March 1, 2020 and July 1, 2021 answered an online questionnaire including 40 WHO standards-based quality measures. Results: A total of 4817 women were included in the analysis. Significant d

Objective To update the epidemiology of anti-neutrophil cytoplasmic antibody-associated vasculitis (AAV) in a defined geographical area of southern Sweden.Methods The study area comprised 14 municipalities with a combined adult population (≥18 years) of 623 872 in 2019. All cases diagnosed with AAV in 1997–2019 in the study area were included in the estimate of incidence. Diagnosis of AAV was veri

Purchasing on the part of a building construction company involves actors inside and outside the organization. These actors are driven by different motives that influence purchasing decisions in different situations. An explicit framework that assists in understanding the different purchasing situations would be of benefit to companies and researchers. Through a study of purchasing theory and pracPurchasing on the part of a building construction company involves actors inside and outside the organization. These actors are driven by different motives that influence purchasing decisions in different situations. An explicit framework that assists in understanding the different purchasing situations would be of benefit to companies and researchers. Through a study of purchasing theory and prac