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Endoglycosidase treatment abrogates IgG arthritogenicity: Importance of IgG glycosylation in arthritis.

The glycosylation status of IgG has been implicated in the pathology of rheumatoid arthritis. Earlier, we reported the identification of a novel secreted endo-beta-N-acetylglucosaminidase (EndoS), secreted by Streptococcus pyogenes that specifically hydrolyzes the beta-1,4-di-N-acetylchitobiose core of the asparagine-linked glycan of human IgG. Here, we analyzed the arthritogenicity of EndoS-treat

Recent advances in the mechanisms and treatment of immune thrombocytopenia

Primary immune thrombocytopenia is an autoimmune disease associated with a reduced peripheral blood platelet count. The phenotype is variable with some patients suffering no bleeding whilst others have severe bleeding which may be fatal. Variability in clinical behaviour and treatment responses reflects its complex underlying pathophysiology. Historically the management has relied heavily on immun

Epitope specificity and isotype of monoclonal anti-D antibodies dictate their ability to inhibit phagocytosis of opsonized platelets

Rh immune globulin (WinRho SDF; Cangene, Mississauga, ON, Canada) is an effective treatment for autoimmune thrombocytopenic purpura; however, maintaining a sustained supply for its use in autoimmune thrombocytopenic purpura and its primary indication, hemolytic disease of the newborn, makes the development of alternative reagents desirable. We compared Rh immune globulin and 6 human monoclonal ant

Lunds universitets internationella fadderprogram - infotext

Bli internationell fadder hösten 2019! Vill du lära dig om nya kulturer? Vill du jobba eller plugga utomlands? Är du intresserad av olika språk (till exempel engelska, spanska eller kinesiska)? I höst kommer cirka 2 000 nya internationella studenter till Lund för att studera vid Lunds universitet. Vi behöver din hjälp med att få dem att känna sig välkomna! Genom att vara internationell fadder är d

https://www.psy.lu.se/sites/psy.lu.se/files/lunds_universitets_internationella_fadderprogram_-_infotext.pdf - 2026-05-10

Our research

Research Areas The research area of clinical and epidemiological research in cognition aims to study risk factors of reduced cognitive ability particularly vascular mechanisms. Another aim entails taking care of already reduced cognitive ability. Several clinical and longitudinal studies have involved mechanisms of interrupted autoregulation of cerebral blood flow, correlation between hypertension

https://www.geriatrik.lu.se/geriatrics/our-research - 2026-05-09

Ministry of imagination

Memories of the transition Memories of the transition is fictive. However, it is knowledge-based speculation. Much of the story is inspired by existing proposals, emerging innovations, or research on the transformations needed to meet our climate targets. We have collected some of these imaginative seeds below so that you can understand and construct your own vision of a post-fossil society. Conte

https://www.climatefutures.lu.se/ministryofimagination - 2026-05-09

Trade Secrets, Big data and Artificial Intelligence Innovation: a Legal Oxymoron?

This chapter will analyse the Trade secret Directive from a technological informed legal perspective, looking at the possibilities and scope of protection that it offers for knowledge based activities and business models. It opens by restating the basic yet important fact that “Information is power”. Asymmetries in information are a fundamental transaction cost and in this sense informational qual

Collecting curiosities : Eighteenth-century Museum Stobaeanum and the development of ethnographic collections in the nineteenth century

In 1735, professor Kilian Stobaeus donated his collections to Lund University laying the foundation for the university’s first museum. The ”Museum Stobaeanum” contained over 3000 natural history, historical and ethnographic objects typical of the cabinets of curiosity. This richly illustrated book is the first comprehensive history of these collections.Eighteen chapters, written by an interdiscipl

The European Frontier : Clashes and Compromises in the Middle Ages

During the Middle Ages the concepts of `them and us' became concrete in the shape of fiercely defended frontiers, some of which were physical, geographic and political, while others were more ideological. This volume, the proceedings of an international symposium held at Lund University in 2000, presents twenty-four papers which examine the archaeological evidence for frontiers across Europe. Divi

Circular business models in Japan : Analysis of circular business transformation through an institutional approach

The circular economy is becoming a globalised phenomenon, but the regional emergence of circular business models differs significantly. By adopting a circular business institutionalisation perspective which bridges theory on institutional work and “ecologies of business models” we study the emergence of circular business models in Japan, a region with recent circular policy and business commitment

Recreating the bonds: Naši ljudi or Yuggar of Sweden The Old Set of Values in the New Environment

This thesis will inquire into the contemporary neo-Yugoslavian culture in Sweden and cultural intimacy as a base to recreate the bonds from the past. Moreover, mutual impacts between the two substantially different societies, the society of free individuals of the Swedes and neo- Yugoslav collectiveness, duh Yuge, are the result of a multifaceted process with intriguing outcomes. Zlatan Ibrahimovi

Fault Tolerance for Real-Time Systems: Analysis and Optimization of Roll-back Recovery with Checkpointing

Popular Abstract in English In the modern world of today, we are surrounded with many electronic devices which offer previously unseen performance. These devices constitute a large part of the everyday consumer electronics such as laptops, tablets, smart phones, etc., but are also used in wide variety of domains such as automotive industry, avionics, medicine, etc. The constant demand for high perIncreasing soft error rates in recent semiconductor technologies enforce the usage of fault tolerance. While fault tolerance enables correct operation in the presence of soft errors, it usually introduces a time overhead. The time overhead is particularly important for a group of computer systems referred to as real-time systems (RTSs) where correct operation is defined as producing the correct re

Receptet på en fantastisk antikropp – Vetenskap och Hälsa

Receptet på en fantastisk antikropp – Vetenskap och Hälsa Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Receptet på en fantastisk antikropp 2024-06-26 Bilden illustrerar två IgG-liknande antikroppar som binder till ett protein. Forskarna Pontus Nordenfelt och Arman Izadi är något av antikroppsdesigners. “Hybr

https://www.vetenskaphalsa.se/receptet-pa-en-fantastisk-antikropp/ - 2026-05-10