Search results

Disturbed haemostasis is a central finding in severe Streptococcus pyogenes infection. In particular, microthrombi are found both at the local site of infection and at distant sites. Platelets are responsible for maintaining vascular function and haemostasis. We report here that M1 protein of S. pyogenes triggers immune-mediated platelet activation and thrombus formation. M1 protein is released fr

Recently, to reach zero emission levels, some new energy systems based on fuel cells have been developed. This paper presents a review of investigations of these systems by thermodynamics performance, mainly, energy and exergy analysis. With energy analysis, the performance of an energy conversion system cannot be effectively and accurately evaluated. But exergy analysis complements and reinforces

This study demonstrates that a cytotoxic serum reactivity not requiring the presence of complement appears in the sera of patients with acute myelogenous leukemia. The reaction is detected upon short‐term incubation of sera in vitro with autochthonous mononuclear white blood cells from peripheral venous blood of patients at the acute stage of the disease. This reactivity was demonstrated in 18/18

Despite the recent clinical success of T cell checkpoint inhibition targeting the CTLA-4 and PD-1 pathways, many patients either fail to achieve objective responses or they develop resistance to therapy. In some cases, poor responses to checkpoint blockade have been linked to suboptimal CD28 costimulation and the inability to generate and maintain a productive adaptive anti-tumor immune response.

14 november är utnämnd till Världsdiabetesdag därför att det är Frederick Bantings födelsedag. Den kanadensiske läkaren Banting har gått till historien som insulinets upptäckare. diabetesportalen.se uppmärksammar dagen med en artikel om den vanligaste och samtidigt mest vedervärdiga diabetesbehandlingen före insulinet – svältkuren. Efter många decenniers vilt experimenterande med mer eller mindre

https://www.diabetesportalen.lu.se/diabeteshistoria/den-vedervardiga-svaltkuren - 2025-11-23

Abstract in German Nach ihrem Amtsamtritt im September 2006 hat die schwedische Mitte-Rechts-Regierung im Januar 2007 die Beiträge zu den Arbeitslosenkassen der Gewerkschaften erheblich erhöht. Dadurch wurde es plötzlich wesentlich teurer, Mitglied in einer Gewerkschaft (und in der Arbeitslosenkasse) zu sein. Innerhalb von zwei Jahren verloren die Gewerkschaften 8% ihrer Mitglieder, der gewerkschaIn January 2007 the Swedish centre-right government in office since September 2006 raised considerably fees for union unemployment funds. Union membership (fund membership included) therefore suddenly became much more expensive. Trade unions lost 8% of their members over two years and union density fell by 6 percentage points (from 77% in 2006 to 71% in 2008), while unemployment funds were hit by

Master’s Dissertation Structural Mechanics JIMMY PERSSON Report TV SM -5181 JIM M Y PERSSO N N U M ER IC A L A N A LY SIS O F C O M PR ESSIO N PER PEN D IC U LA R TO TH E G R A IN IN G LU LA M B EA M S W ITH A N D W ITH O U T R EIN FO R C EM EN T NUMERICAL ANALYSIS OF COMPRESSION PERPENDICULAR TO THE GRAIN IN GLULAM BEAMS WITH AND WITHOUT REINFORCEMENT Detta är en tom sida! Copyright © 2011 by Str

https://www.byggmek.lth.se/fileadmin/byggnadsmekanik/publications/tvsm5000/web5181.pdf - 2025-11-20

The gene for an IgA-binding protein from a group A streptococcal strain was cloned and expressed in Escherichia coli. The IgA-binding protein, called protein Arp, was purified on IgA-Sepharose, allowing complete purification in a single step. Analysis of protein Arp by Western immunoblotting demonstrated a major IgA-binding band, with an apparent molecular weight of 42 kD. The purified protein was

Pareto optimality is a concept that formalises the trade-off between a given set of mutually contradicting objectives. A solution is said to be Pareto optimal when it is not possible to improve one objective without deteriorating at least one of the other. A set of Pareto optimal solutions constitute the Pareto front. The Pareto concept applies well to the inverse planning process, which involves

Background. Anti-glomerular basement membrane (anti-GBM) disease often results in end-stage renal failure despite therapy with plasma exchange and immunosuppressive drugs. The newly discovered streptococcal enzymes IgG-degrading enzyme of S.pyogenes (IdeS) and endoglycosidase S (EndoS) act with remarkable specificity on circulating IgG. In this study, we investigate their ability in vivo to preven

In the study presented in this paper, the effect of different vehicle driving cycles on the pneumatic hybrid has been investigated. The pneumatic hybrid powertrain has been modeled in UT-Power and validated against experimental data. The GT-Power engine model has been linked with a MATLAB/simulink vehicle model. The engine in question is a single-cylinder Scania D12 diesel engine, which has been c

Ord i mörkret Version 2 % α 33 ιœ Det œ œµ œ∀ œ œ œ bor så myc ket i D m G/D A œ œ∀ œ œ œµ or den, de är E/D A/C∀ œ œ œ œµ œ∀ œ fyll da av sa go lik D m G ˙∀ Œ ‰ ιœ kraft. Är A - - - - - % α5 œ œµ œ∀ œ œ liv li nor na på D m G/D œ œ∀ œ ‰ ιœµ jor den, de E/D A/C∀ œ œ œ œµ œ œ∀ bäs ta vi nå gon sin D m G A ˙ Œ œ haft. De D m C 7 - - -- - - - % α9 œ œ œ œ œ föl jer oss ge nom F C/F B œ œ œ œ œ œ å re

https://www.mhm.lu.se/sites/mhm.lu.se/files/2022-04/Ord%20i%20mo%CC%88rkret%20%20-%20obligatorisk%20sa%CC%8Ang%20acapella%20Sa%CC%8Ang%20GF%202022_0.pdf - 2025-11-21

Skippa socker och stärkelse – lika effektivt vid IBS som rådande rekommendation – Vetenskap och Hälsa Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Skippa socker och stärkelse – lika effektivt vid IBS som rådande rekommendation 2024-09-26 Symtomen hos patienter med mag-/tarmsjukdomen IBS förbättrades lika myc

https://www.vetenskaphalsa.se/skippa-socker-och-starkelse-lika-effektivt-vid-ibs-som-radande-rekommendation/ - 2025-11-22

Lymphocytes from human peripheral blood were separated by Countercurrent distribution (CCD) in a charged aqueous two-phase system composed of Dextran T 500 and polyethylene glycol 6000. Maximal responses to the T-cell mitogens phytohemagglutinin and concanavalin A were detected in a part of the distribution corresponding to the area where the highest percentage of E rosetting cells were seen. Anti

Popular Abstract in Swedish Vår forskningsgrupp har tidigare påvisat kraftiga förändringar i genuttryck för neurotrofiner, en familj av tillväxtfaktorer för nervceller, och deras receptorer i kortikala och hippokampala nervceller vid olika hjärnskador. Det är till stora delar okänt vilken funktion neurotrofiner har efter hjärnskador, men neurotrofinsvaret skulle kunna vara en skyddande mekanism ocThis study explores the role of brain-derived neurotrophic factor (BDNF) for neuronal vulnerability and neurogenesis following cerebral ischemia in the rat. Cerebral ischemia results in selective neuronal cell loss in specific brain regions. We here demonstrate the rank order of vulnerability in two regions affected by global forebrain ischemia, i.e., hippocampus and striatum, by combining specifi

Protein ADP-ribosylation is a reversible post-translational modification that regulates important cellular functions. The identification of modified proteins has proven challenging and has mainly been achieved via enrichment methodologies. Random mutagenesis was used here to develop an engineered Af1521 ADP-ribose binding macro domain protein with 1000-fold increased affinity towards ADP-ribose. T