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IgG glycan hydrolysis by EndoS inhibits experimental autoimmune encephalomyelitis
Relational problems and psychiatric symptoms in couple therapy
Lundblad A-M, Hansson K. Relational problems and psychiatric symptoms in couple therapyInt J Soc Welfare 2005: 14: 256 -264 c Blackwell Publishing, 2005.This article describes couples attending family counselling in Sweden. The study group is compared with clinical groups and non-clinical groups. Self-rating instruments were com-pleted by 317 women and 312 men to evaluate the following: marital sa
IVIg inhibits reticuloendothelial system function and ameliorates murine passive-immune thrombocytopenia independent of anti-idiotype reactivity
CCL25/CCR9 promotes the induction and function of CD103 on intestinal intraepithelial lymphocytes.
The integrin CD103 and the chemokine receptor CCR9 are co-expressed on small intestinal CD8+ intraepithelial lymphocytes (IEL), naïve murine CD8+ T cells and by a small population of effector/memory CD8+ T cells, indicating a potential role for CCR9 in regulating CD103 expression and function. Here, we demonstrate that CD103, in contrast to CCR9, is down-regulated on CD8+ T cells following their a
20240528 Skapa Bättre Powerpoint-presentationer Karin Lilja
Skapa bättre och mer tillgängliga powerpoints Sida 1 av 7 Skapa bättre och mer tillgängliga powerpoints Stödanteckningar för Karin Liljas presentation 28 maj 2024. Grundupplägget handlar om att göra powerpoints bättre och lättillgängliga för alla, oavsett utmaningar. Här kan man jämföra med engreppsblandaren som togs fram av tillgänglighetsskäl men som numera är standard för alla. Så det blir inga
Studies of bacterial surface proteins interacting with the immune system
Popular Abstract in Swedish En av de viktigaste substanserna i vår kropp är proteiner, också kallade äggviteämnen. Proteiner har en mängd olika uppgifter i kroppen, de finns i våra celler där de har olika uppgifter såsom att fungera som enzymer, transportörer, signalsubstanser, eller som skyddsfaktorer. Proteiner ingår också som viktiga beståndsdelar i vävnaderna mellan cellerna och finns dessutomPathogenic bacteria express a wide array of surface proteins that interact with the environment. Many of these proteins are believed to be important for the virulence. This thesis deals with the binding of immunoglobulins (Ig) and complement regulating proteins to certain bacterial surface proteins. Protein L from Peptostreptococcus magnus binds to Igk-light chains while protein A from Staphylococ
GLOWKeynote
GLOWKeynote Constraining Local Dislocation dialect-geographically Gertjan Postma Meertens Instituut Amsterdam gertjan.postma@meertens.knaw.nl GLOW-36, Lund, 3-5 April 2013 V-T-AGR versus V-AGR-T in Dutch dialects 1 Structure • The problem: order reversal - syntax or postsyntax? • The role of dialectology • Deviant structures V-pron-T and V-AGR-T in Dutch • A fundamental isogloss cuts the Dutch dia
https://konferens.ht.lu.se/fileadmin/user_upload/sol/ovrigt/konferens_glow36/Handouts_and_Presentations/Postma.pdf - 2025-11-20
Chimeric antibody-binding Vitreoscilla hemoglobin (VHb) mediates redox-catalysis reaction: new insight into the functional role of VHb : new insight into the functional role of VHb
Specialgjorda antikroppar i kampen mot infektioner – Vetenskap och Hälsa
Specialgjorda antikroppar i kampen mot infektioner – Vetenskap och Hälsa Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Specialgjorda antikroppar i kampen mot infektioner 2025-05-21 Bilden är en illustration av ett SARS-CoV-2-virus (rosa) De gula utskotten på dess yta är de så kallade spike-proteinerna. De blå
https://www.vetenskaphalsa.se/specialgjorda-antikroppar-i-kampen-mot-infektioner/ - 2025-11-22
IdeS, a novel streptococcal cysteine proteinase with unique specificity for immunoglobulin G.
Recent work from several laboratories has demonstrated that proteolytic mechanisms significantly contribute to the molecular interplay between Streptococcus pyogenes, an important human pathogen, and its host. Here we describe the identification, purification and characterization of a novel extracellular cysteine proteinase produced by S.pyogenes. This enzyme, designated IdeS for Immunoglobulin G-
LU-gemensamt Mejlutskick Nr 20-v22-2021
NYTT FRÅN LUNDS UNIVERSITET Mejlutskick på svenska och engelska som vänder sig till fakultetskommunikatörer vid Lunds universitet för vidarespridning i fakultets- och institutionskanaler – Nr 20 v 22 - 2021. UNIVERSITETSGEMENSAMT Lönerevisionen drar ut på tiden Förhandlingarna med anledning av lönerevisionen pågår fortfarande. Tyvärr kan det konstateras att det nu har dragit ut så långt i tiden at
https://www.cec.lu.se/sites/cec.lu.se/files/2021-06/LU-gemensamt%20Mejlutskick%20Nr%2020-v22-2021.pdf - 2025-11-21
Bacterial modulation of host glycosylation - in infection, biotechnology, and therapy
Popular Abstract in Swedish Hur gör bakterier för att komma undan immunförsvaret? Vi har studerat hur en vanligt förekommande bakterie, grupp A streptokocker, gör för att undvika kroppens immunförsvar vid infektion. Vi har upptäckt enzymer som bidrar till bakteriens förmåga att undvika immunförsvaret genom att avväpna antikroppar. De bakteriella enzymerna kan användas i bioteknisk industri och eveA majority of the proteins of the immune system are glycosylated and the glycans of IgG are essential for its functionality. Bacteria display enzymes that modulate the glycans of the immune system to weaken the host defense and favor bacterial survival. In this thesis we aimed at exploring bacterial modulation of host glycosylation in infection and to evaluate the usefulness of bacterial enzymes i
Eosinophil granulocyte interaction with serum-opsonized particles: binding and degranulation are enhanced by tumor necrosis factor alpha
Eosinophils participate in the inflammatory response seen in allergy and helminthic infestation. Their release of granule-bound cationic proteins may play a role in these diseases. Therefore, we investigated mechanisms involved in the release of eosinophil cationic protein (ECP). Serum-opsonized zymosan was phagocytosed by eosinophils, and ECP was released into the phagosomes as judged by immunoel
Analysis of the molecular interplay between Streptococcus pyogenes and its human host
The common human pathogen Streptococcus pyogenes is the causative agent of numerous mild and severe clinical conditions. It expresses a number of secreted or cell wall-anchored proteins that modulate the human immune system and facilitate colonization and spread of the pathogen in the human host. During S. pyogenes infections, human plasma leaks into the site of infection as a consequence of infl
Evasion of phagocytosis through cooperation between two ligand-binding regions in Streptococcus pyogenes M protein.
The M protein of Streptococcus pyogenes is a major bacterial virulence factor that confers resistance to phagocytosis. To analyze how M protein allows evasion of phagocytosis, we used the M22 protein, which has features typical of many M proteins and has two well-characterized regions binding human plasma proteins: the hypervariable NH2-terminal region binds C4b-binding protein (C4BP), which inhib
Two major classes in the M protein family in group A streptococci
The M protein family of molecules in the group A streptococcus comprises a number of cell surface proteins that interact with the immune system of the host. One of the proteins in this family is the IgA receptor Arp4, which has C repeats similar to those that characterize the known M proteins. The streptococcal strain expressing Arp4 also expresses a second immunoglobulin-binding protein, Mrp4, wh
New treatments in hemophilia: insights for the clinician.
Hemophilia has evolved from an often fatal hereditary bleeding disorder to a disorder for which safe and effective treatment is available. However, there are several challenges remaining in the treatment of hemophilia. Prophylaxis to prevent bleeding is costly and requires frequent intravenous injections, which are cumbersome for patients. Venous access is often difficult to achieve, especially in
