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Background: Single-nucleotide polymorphisms in genes involved in pain control might predispose to exaggerated sensitivity or difference in opioid analgesic effect. The relevance of the KCNJ6 -1250G>A (rs6517442, c.-1787G>A) and the catecholamine-O-methyltransferase (COMT) c.472G>A (rs4680, Val 158 Met) single-nucleotide polymorphisms were studied in preterm infants needing intubation and randomize

We report the discovery of a hot (Teq ≈ 1055 K) planet in the small-planet radius valley that transits the Sun-like star TOI-733. It was discovered as part of the KESPRINT follow-up program of TESS planets carried out with the HARPS spectrograph. TESS photometry from sectors 9 and 36 yields an orbital period of {equation presented} days and a radius of {equation presented}. Multi-dimensional Gauss

Globally, the lifespan of populations increases but the healthspan is lagging behind. Previous research showed that survival into extreme ages (longevity) clusters in families as illustrated by the increasing lifespan of study participants with each additional long-lived family member. Here we investigate whether the healthspan in such families follows a similar quantitative pattern using three-ge

A new aromatic pair, 2-hydroxy-6-methoxybenzamide/1-methylpyrrole at the terminal position of hairpin polyamides has been designed for distinguishing T·A from A·T base pairs and both from G·C/C·G in the minor groove of DNA. Four eight-ring hairpin polyamides with benzamide (Bz), 2-hydroxybenzamide (Hb-1), 2-hydroxy-6-methylbenzamide (Hb-2), and 2-hydroxy-6-methoxybenzamide (Hb-3) at the N-terminal

This paper presents a statistical combination of searches targeting final states with two top quarks and invisible particles, characterised by the presence of zero, one or two leptons, at least one jet originating from a b-quark and missing transverse momentum. The analyses are searches for phenomena beyond the Standard Model consistent with the direct production of dark matter in pp collisions at

Within the local energy independent pseudopotential theory, a convergent supercell calculation of the position of the discrete impurity level produced by the neutral undistorted vacancy in silicon has been performed. Translational symmetry was reintroduced by placing the impurities on a Bravais lattice. The author made calculations with unit cells containing up to 2662 atoms plus vacancy. A deep l

Protein E (PE) is a ubiquitous multifunctional surface protein of Haemophilus spp. and other bacterial pathogens of the Pasteurellaceae family. H. influenzae utilizes PE for attachment to respiratory epithelial cells. In addition, PE interacts directly with plasminogen and the extracellular matrix (ECM) components vitronectin and laminin. Vitronectin is a complement regulator that inhibits the for

A method was developed, which drives the selection of appropriate solar control mechanisms based on theanalysis of overheating due to solar heat gains. The aim of the method is to maintain adequate thermalcomfort levels in highly glazed spaces. Two thermal comfort models, Predicted Mean Vote and AdaptiveModel, were chosen to set the thermal comfort boundaries included in the method. Moreover, in o

Charged Higgs bosons heavier than the top quark and decaying via H± → tb are searched for in proton-proton collisions measured with the ATLAS experiment at (Formula presented.) TeV corresponding to an integrated luminosity of 20.3fb−1. The production of a charged Higgs boson in association with a top quark, gb → tH±, is explored in the mass range 200 to 600 GeV using multi-jet final states with on

Protein L, a cell wall molecule of certain strains of the anaerobic bacterial species Peptostreptococcus magnus, shows high affinity for human immunoglobulin (Ig) light chains. In the present study protein L was tested against a panel of human myeloma proteins of the IgG, IgM, IgA and IgE classes, and strong binding was seen with antibodies carrying kappa light chains. A high degree of specificity

Purpose: By studying different sets of data divided by type of economic political context, this thesis investigates if the usage of accounts differs between countries. In more specific, the purpose of this thesis is to investigate if the use of accounts in the CEO letters of Swedish-, UK- and German-based companies differ as a result of having businesses in different political economies. Theoreti

In this work, two LNAs operating at a frequency around 83 GHz and 110 GHz, for satellite- and 5G applications respectively, have been designed, using vertical InGaAs nanowire transistors. In addition, a switch operating at a frequency around 110 GHz has been designed. The topology has consisted of a common source as a first stage, and a cascode as a second stage. The design and simulations of the

This thesis aims to provide a suggestion to how a chair could be designed to have less negative impact on the environment. At many offices the turnover of furniture is big. By conducting interviews and study visits, it was indicated that chairs used in lunch areas and meeting rooms are the type of furniture that gets exchanged the most in office environments. Many of the existing chairs used for t

Arbetspsykologiska personlighetstest används numera ofta vid rekrytering och matchning på arbetsmarknaden. Det är därför viktigt att utvärdera de test som används på området. Den aktuella studiens syfte var att utvärdera egenskaper hos den svenska versionen av det arbetspsykologiska personlighetstestet Shapes Management genom att mäta dess konvergenta validitet mot den svenska versionen av det välOccupational personality questionnaires are increasingly being used in the process of recruitment, and the matching between individuals and jobs, on the contemporary labor market. Evaluation and development of questionnaires that are in use is therefore important. The purpose of this study was to evaluate the Swedish version of the occupational personality questionnaire Shapes Management by measur

Miljö- och klimatfrågor blir alltmer aktuella i samhället. Såväl konsumenter som företag och internationella organisationer lägger större fokus på dessa frågor. Exempelvis använder företag ofta miljöpåståenden i sin marknadsföring, det vill säga påståenden som skapar intrycket att en produkt har en positiv inverkan, saknar inverkan eller har en mindre inverkan på miljön än andra produkter. DärtillEnvironmental and climate issues are becoming increasingly relevant in society. Both consumers and companies, as well as international organizations are placing greater focus on these issues. For example, companies often use environmental claims in their marketing, making statements that create the impression that a product has a positive impact, no impact or a lesser impact on the environment com

This research explores the interplay between strategic communication and legitimacy in United Nations (UN) peacekeeping missions, focusing on the United Nations Stabilization Mission in the Democratic Republic of Congo (MONUSCO) and addresses the challenge of maintaining and establishing legitimacy through strategic communication during crises. The study specifically investigates the use of strate