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Nociceptive transmission to rat primary somatosensory cortex - comparison of sedative and analgesic effects.

CO(2)-laser C-fibre evoked cortical potentials (LCEPs) is a potentially useful animal model for studies of pain mechanisms. A potential confounding factor when assessing analgesic effects of systemically administered drugs using LCEP is sedation. This study aims to clarify: 1) the relation between level of anaesthesia and magnitude of LCEP, 2) the effects of a sedative and an analgesic on LCEP and

Accelerator Mass Spectrometry

In this overview the technique of accelerator mass spectrometry (AMS) and its use are described. AMS is a highly sensitive method of counting atoms. It is used to detect very low concentrations of natural isotopic abundances (typically in the range between 10(-12) and 10(-16)) of both radionuclides and stable nuclides. The main advantages of AMS compared to conventional radiometric methods are the

Maintenance of genetic variation and moderate differentiation among populations under sex-biased dispersal in the common vole Microtus arvalis in patchy habitats

We present a microgeographic analysis of 34 allozyme loci and the control region of mitochondrial DNA (mtDNA) in the common vole Microtus arvalis (Pallas, 1779), performed to assess the effects of environmental heterogeneity on the distribution of genetic variation among populations in the Biebrza river valley, NE Poland The common vole occurs there in two types of habitat open grassland and pastu

Somatic and anxiety symptoms of depression are associated with disability in late life depression

Objectives: To assess the relationships of somatic and anxiety symptoms of depression with functional disability in a sample of older adults with late life depression. Method: Data were analyzed from 78 older adults aged 65–88 with current major depression. Somatic and anxiety symptoms from the 24-item Hamilton Depression Rating Scale (HDRS) were summed to create variables measuring severity of th

Synchrotron X-ray study of vacuum brazed 316L stainless steel joints

Nickel phosphide is a valuable material in high-temperature brazing and joining applications, offering excellent thermal stability for temperatures up to 400°C. Nickel phosphide is used as powder form for joining applications and therefore it is imperative to study the formation as well as interaction of Ni2P particles with Brazing with nickel-chromium-based fillers is widely used to join stainles

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Through a comparative analysis of works by street artists Faile and Banksy, from both the street and the gallery, I make the point that the field of modern street art is not as homogenous as the media and the established art world often portray it. By differentiating between sub- and counter-cultural agents, I point out the span of social and ideological backgrounds within the street art culture a

TEN-T finansiering av Svenska järnvägsprojekt

In today´s society, it is obvious to travel in a convenient and simple way around the world. Unfortunately the development of the compatibility for the railway between nations is behind in the EU. This is a problem that has been observed in Europe and every year, much money is spent to secure cross-border transports. TEN-T EA is an organization that was founded for the EU member states to apply fo

Using Social CRM to influence Customer Service and Loyalty: A Perspective in the Airline Industry

The purpose of the study was to investigate how companies can harness the power of social media by utilizing Social CRM. It was investigated how integrating social media channels into existing Client Relationship Management platforms can influence customer service and customer loyalty. A mixture of both qualitative and quantitative research methods with an abductive approach was used. The researc

Kyrkan som välfärdsaktör

Abstract The aim of this study was to describe and analyze the church’s social work, with socially vulnerable individuals, in a municipality in the southern part of Sweden. The church of Sweden has a history of social work because it was a state church until 2000. Since the separation it has been defined as any other faith-communities. Therefore this study includes other faith-communities within

Närståendes tillfredsställelse med vård, information och beslut på intensivvårdsavdelningar

Närståendes närvaro hos patienter som är kritiskt sjuka underlättar enligt studier patienternas vistelse på intensivvårdsavdelningen. För att stödja och tillhandahålla information till de närstående bör personal på intensivvårdsavdelningar vara medvetna om närståendes uppfattningar. I Kanada har ett enkätformulär FS-ICU utvecklats för att undersöka närståendes tillfredsställelse med vården och med

Patienters förväntningar och upplevelser på postoperativ smärta och smärtlindring

Trots att kunskaperna om och intresset för smärta och smärtlindring har ökat de senaste åren drabbas fortfarande många patienter en inadekvat smärtlindring och många patienter förväntar sig smärta postoperativt. Syftet med denna studie var att undersöka kvinnor i olika åldrar avseende förväntningar och upplevelser av postoperativ smärta och smärtlindring samt hur stor betydelse den preoperativa in

Determination of N-methylsuccinimide and 2-hydroxy-N-methylsuccinimide in human urine and plasma

A method for determination of N-methylsuccinimide (MSI) and 2-hydroxy-N-methylsuccinimide (2-HMSI) in human urine and of MSI in human plasma was developed. MSI and 2-HMSI are metabolites of the widely used organic solvent N-methyl-2-pyrrolidone (NMP). MSI and 2-HMSI were purified from urine and plasma by C8 solid-phase extraction and analysed by gas chromatography-mass spectrometry in the negative

Natural history of patients with unoperated atherosclerotic carotid artery disease--results from a retrospective study

The natural history of carotid artery disease was studied in a retrospective study of 609 angiograms performed during 1969-1979 on patients who had subsequently not been operated on. The indication for angiography differed, but was aimed at clarifying suspected cerebrovascular events. 578 patients could be followed-up after a median time of 10.4 years (0-22). The median survival time after angiogr

SweDCIS: Radiotherapy after sector resection for ductal carcinoma in situ of the breast. Results of a randomised trial in a population offered mammography screening

We studied the effect of postoperative radiotherapy (RT) after breast sector resection for ductal carcinoma in situ (DCIS). The study protocol stipulated radical surgery but microscopically clear margins were not mandatory. We randomised 1046 operated women to postoperative RT or control between 1987 and 1999. The primary endpoint was ipsilateral local recurrence. Secondary endpoints were contrala

A population-based cohort study of KIR genes and genotypes in relation to cervical intraepithelial neoplasia

Natural killer (NK) cells are involved both in control of virus infections and in elimination of tumor cells. Killer immunoglobulin-like receptors (KIRs) either activate or inhibit NK cell-mediated cytolysis, protecting healthy cells from destruction while enabling killing of abnormal cells. To investigate whether KIR genes or genotypes are associated with cervical carcinogenesis, a nested case-co

On the interaction between two fixed spherical particles

The variation of the drag (CD) and lift coefficients (CL) of two fixed solid spherical particles placed at different positions relative each other is studied. Simulations are carried out for particle Reynolds numbers of 50, 100 and 200 and the particle position is defined by the angle between the line connecting the centers of the particles and the free-stream direction (a) and the separation dist

Weight loss and body mass index in relation to aspiration in patients treated for head and neck cancer: a long-term follow-up

Persistent severe swallowing dysfunction with aspiration is a common and sometimes overlooked sequelae after treatment for squamous cell carcinoma of the head and neck (SCCHN) and may impact food intake and nutritional status. More knowledge is needed to increase the understanding of severe swallowing dysfunction as a risk factor for persistent nutritional deteriorations in SCCHN survivors. The pu