Search results

Background In placebo-controlled trials, reslizumab, an anti-IL-5 monoclonal antibody, significantly reduced asthma exacerbations and improved lung function and asthma control in patients with eosinophilic asthma. Objective This open-label extension study evaluated safety and efficacy of reslizumab for up to 24 months. Methods After participation in 1 of 3 placebo-controlled, phase III trials in m

Facial beat gestures align with pitch accents in speech, functioning as visual prominence markers. However, it is not yet well understood whether and how gestures and pitch accents might be combined to create different types of multimodal prominence, and how specifically visual prominence cues are used in spoken communication. In this study, we explore the use and possible interaction of eyebrow (

Blood transfusion is a clinically significant and crucial process, which saves millions of lives every year. However,shortage of donated blood and the risk of virus transmission through transfusible blood seriously affect theavailability of the blood. Hemoglobin (Hb), owing to its oxygen carrying capacity, has been studied as a startingmaterial for the development of artificial blood substitutes/H

The analysis of surface wave dispersion curves is a way to infer the vertical distribution of shear wave velocity. The range of applicability is extremely wide: going, for example, from seismological studies to geotechnical characterizations and exploration geophysics. However, the inversion of the dispersion curves is severely ill-posed and only limited efforts have been put in the development of

At the 100 years anniversary in 2020 of the Reunion around 650 memorials have been protected. The memorials are to be found all over Denmark, where they constitute the largest group. The time of their erection, the localization, design, inscriptions, pictures and initiators are relatively well known. The article investigates two main questions. Firstly, why have so many memorials for the Reunion b

This thesis explores the European Commission’s proposal on General Reverse Charge Mechanism. VAT is a final tax on consumption. It is imposed on every transaction in the supply chain with the general aim of being deductible and thus being neutral for businesses with the right to deduct. The initial aim of the VAT system was to operate as if all the transactions occurred in one single country; howe

Biomolekyler, så som proteiner, produceras genom att DNA som kodar för dessa molekyler tillsätts i celler. Cellerna kan exempelvis vara bakterier, jäst eller från däggdjur. Dessa celler producerar inte enbart de önskade proteinerna utan även andra proteiner som är nödvändiga för att cellerna ska kunna överleva. Som en följd av detta är upprening en av de viktigaste processerna i produktionen av prDownstream processing is an essential part in the production of biomolecules and the optimization of these processes are of great value, since they can be both time consuming and expensive. One common type of enzyme used in different biotechnical approaches is proteases and in this study Protease X was investigated. In order to use the enzyme in a process, a purification procedure needs to be esta

I svensk aktiebolagsrätt finns en grundläggande princip om att aktier fritt ska kunna överlåtas mellan olika rättssubjekt. Trots att principen får anses vara skyddsvärd har lagstiftaren stadgat tre undantag från principen: hembud, förköp och samtycke. Undantagen – kallade överlåtelsebegränsningar – kan införas i bolagsordningen och utgör i praktiken kontrollprocesser genom vilka befintliga aktieägAn essential principle in the Swedish company law is the principle of free transferability of shares. The signification of the principle is to ensure the free transfer of shares between different legal entities. Despite the fundamental nature of the principle, the lawmaker has granted three exceptions to the principle: a post-sale purchase right clause, a right of first refusal clause and a conten

The transition to farming in the coastal environments of southern Scandinavia remains a key conundrum in European prehistory. This region was heavily exploited by Late Mesolithic communities of the Ertebølle culture, complex hunter-fisher-gatherers who flourished for some 1500 years prior to the arrival of farming at around 4000 BCE marking the start of the Neolithic period. Extensive genetic and

A great amount of financial statements of Swedish companies are registered with the Swedish companies registration office, Bolagsverket, as paper copies. These copies are then scanned and made available to the public as image-PDFs, meaning the financial information contained in them is not digitised and therefore not easily processed in an automated manner. Being able to do so, is valuable however

Buildings worldwide account for 30% of energy consumption and Heating, Ventilation and Air Conditioning (HVAC) represent roughly 38% of a building’s consumption. Therefore, energy savings are crucial for sustainability. The complexity of buildings, with diverse physical domains and large-scale components, presents challenges to achieving energy-efficient operation. Implementing high-performance co