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nutrients Article Daily Intake of Milk Powder and Risk of Celiac Disease in Early Childhood: A Nested Case-Control Study Elin M. Hård af Segerstad 1, Hye-Seung Lee 2, Carin Andrén Aronsson 1 ID , Jimin Yang 2, Ulla Uusitalo 2, Ingegerd Sjöholm 3, Marilyn Rayner 3 ID , Kalle Kurppa 4, Suvi M. Virtanen 5, Jill M. Norris 6, Daniel Agardh 1,* ID and on behalf of the TEDDY Study Group 1 The Diabetes an
Uronate isomerase (EC 5.3.1.12; URI) catalyzes uronate sugar interconversion, a key step in bacterial metabolism, yet its reaction mechanism remains poorly understood. This study delineates the detailed mechanism for the isomerization of d-glucuronate to d-fructuronate catalyzed by a Zn2+-dependent URI enzyme (from Bacillus halodurans). Using quantum mechanical (QM) cluster calculations, three mec
Both high-mountain rivers and wet-based mountain glaciers are considered effective erosion agents. They acted alternatively or simultaneously during the late Quaternary in the Tatra Mountains (West Carpathians) thus producing a vast amount of clastic material that was subject to deposition, reworking and transportation downstream. A small fraction of that amount of the material is still preserved
The genetic changes underlying the development and progression of male breast cancer are poorly understood. Germline BRCA2 mutations account for a significant part of male breast cancer, but the majority of patients lack a known inherited predisposition. We recently demonstrated that the progression of breast cancer in female carriers of a germline BRCA1 or BRCA2 mutation follows specific genetic
Optimization of hexyl-beta-glycoside synthesis from lactose in hexanol at low water activity and high temperature was investigated using beta-glycosidases from hyperthermophilic organisms: Sulfolobus solfataricus (LacS) and Pyrococcus furiosus (CelB). The method for water activity adjustment by equilibration with saturated salt solutions was adapted for use at high temperature. The influence of en
The aim was to determine whether outcome of unrelated donor transplantation for severe aplastic anemia has improved in recent years and whether this is due to patient selection or better transplant technology. We analyzed 498 patients transplanted during 1990-2005. By running univariate regression models dichotomizing year of transplantation we defined 1998 as the year of the most significant chan
Following the development of large-scale use of biomass energy in the EU, international biofuel trade is a plausible scenario and something that is already taking place in Northern Europe. This paper focuses on Swedish biofuel imports, both direct and indirect imports, the latter which derive from the fact that part of the imported pulpwood and timber end up as fuel. The objective is to describe t
We investigated the role of blood components in the adhesion of staphylococci to biological and artificial surfaces under well-defined flow conditions by using the Cone and Plate(let) Analyzer. An enzyme-linked immunosorbent assay-like binding assay with biotinylated bacteria determined the extent of bacterial adhesion to subendothelial extracellular matrix (ECM), polystyrene (PS) and adult bovine
Background-Leukocyte concentration in blood is a classical marker of systemic inflammation. Whether high leukocyte counts are associated with incidence of heart failure (HF) is unknown. This population-based study explored whether the leukocyte concentrations were associated with incidence of hospitalizations due to HF. Methods and results-Leukocyte counts were measured in 16 940 men from the gene
The thermoresponsive copolymer of N-isopropylacrylamide (NIPAM) with 1-vinylimidazole (VI), poly(NIPAM-VI), synthesized by radical polymerization has been used to purify the histidine-tagged green flourescent protein (His-tag GFP) from recombinant E. coli by metal-chelate affinity precipitation. The purified protein was immobilized on the BIAcore sensor chip by carbodiimide coupling. Affinity bind
The co-adsorption of Cd(II) and glyphosate (N-(phosphonomethyl)glycine, PMG) at the manganite (gamma-MnOOH) surface has been studied in the pH range 6-10 at 25 degrees C and with 0.1 M Na(Cl) as ionic medium. Batch adsorption experiments, Fourier transform infrared spectroscopy (FTIR), X-ray photoelectron spectroscopy (XPS) and extended X-ray absorption fine Structure (EXAFS) spectroscopy were use
The purpose of the present study is to assess QT-interval measurements from the EASI 12-lead electrocardiogram (ECG) as compared with the standard 12-lead ECG. The QT interval was automatically determined in simultaneously recorded standard and EASI 12-lead ECGs, using a validated wavelet-based delineator. The agreement between the 2 sets of measurements was quantified both on a lead-by-lead basis
The native bee fauna provides an important ecosystem function, but a large proportion of this fauna in Europe is threatened as a result of habitat loss and fragmentation. The solitary bee Andrena hattorfiana is specialised on collecting pollen from the plant-family Dipsacaceae. In northern Europe the major pollen resource is the insect-pollinated herb Knautia arvensis. We quantified the available
Postal address Lunds universitet, Box 117, 221 00 Lund Visiting address Scheeletorget 1, Medicon Village Telephone 046-222 00 00 Email sara.naurin@fs.lu.se, johanna.mellgren@fs.lu.se Website www.fs.lu.se Research Serv ices Johanna Mel lgren & Sara Naur in Research funding adv isors Lund University’s internal management rules for applications to the Knut and Alice Wallenberg Foundation – grants for
https://www.staff.lu.se/sites/staff.lu.se/files/2021-05/Management%20Rules%20KAW2022_finished.pdf - 2026-05-26
Aim: To investigate the therapeutic effects of fluorouracil (5-Fu) and octreotide (Oct) continuous regional arterial infusion (CRAI,) alone or in combination, was administered in a canine model of severe acute pancreatitis (SAP). Materials and Methods: The animals were divided into five groups; group A (Sham), group B (SAP), group C (SAP and 5-Fu), group D (SAP and Oct), and group E (SAP and 5-Fu
In this study we have investigated whether the carbon isotopic signature differs between different groups and species of marine phytoplankton depending on growth phase, nutrient conditions and salinity. The 15 investigated algal species, representing the Bacillariophyceae, Chlorophyceae, Cryptophyceae, Cyanophyceae, Dinophyceae and Haptophyceae classes were grown in batch monocultures and analysed
A cochlear implant (CI) is a device that provides individuals with severe to profound hearing impairment (SPHI) with auditory stimulation, which makes it possible for them to develop skills related to spoken communication. We have little knowledge about how hearing with a CI influences cognitive and communicative development and there is a need for development of methods for assessment. The genera
Most of the experiments related to quantum information applications, involving rare-earth doped inorganic crystals, are performed on yttrium orthosilicate single crystals. The work presented here is motivated by the search of new compounds which can be used in the field of quantum computing and/or quantum storage. Relaxation times and hyperfine structure of the H-3(4)(0)-> D-1(2)(0) transition in
OBJECTIVE - To elucidate whether family characteristics and stressful life events were associated with onset of autoimmune type 1 diabetes in young adults. RESEARCH DESIGN AND METHODS - This investigation was based on a nation-wide study (Diabetes Incidence Study in Sweden) of newly diagnosed patients aged 15-34 years. Patients clinically classified as type 1 diabetic with antibodies to islet cell
