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In archaeology, we face a unique situation where our primary research method is destructive; excavation as a recording method can only be conducted once. But with the introduction of modern 3D recording methods, much of the process of excavation can be saved and reused. But at the same time, we must overcome the difficulties of examining sites where the data recorded has been accumulated over vast
BackgroundA common genetic variant (rs10993994) in the 5' region of the gene encoding β-microseminoprotein (MSP) is associated with circulating levels of MSP and prostate cancer risk. Whether MSP levels are predictive of prostate cancer risk has not been evaluated.MethodsWe investigated the prospective relationship between circulating plasma levels of MSP and prostate cancer risk in a nested case-
2D resistivity modelling was done in order to examine the imaging resolution of 4 different configurations for mapping of fracture zones in bedrock. The studied arrays include Dipole-dipole, Gradient, Pole-dipole and Wenner. A variety of geological models were tested and the imaging possibilities and limitations of the different arrays were analysed. Apart from imaging fracture zones with various
We describe a simple method to detect significant changes of the total ozone column from global (diffuse and direct) zenith sky measurements taken at the Earth’s surface. The calculation of the total ozone column relies on measured irradiance at two wavelengths in the ultra violet part of the solar spectrum. One of these (i.e. 306 nm) are appreciable absorbed by ozone whereas the other (i.e. 360 n
The Bangladeshi Gen Zs and university students demonstrated a revolutionary example of civic engagement, participatory culture, subcultural identity formation, and reformation during the Student Quota Reform Movement in July, leading to the July massacre where thousands of protesting students were tortured and shot to death in public. The movement happened as an enraged response against the announ
Problem - Uncertainty greatly burdens innovation in tech-driven industries which has made decision-making an art-like navigation, especially within the Fuzzy Front End of operations. This has motivated previous researchers to study the effectual decision-making principles originated by Sarasvathy in regard to a wide variety of audiences such as entrepreneurs, start-ups and top management. Employee
To allow further device scalability within the data storage industry there needs to be continued research of new technologies. One promising technology is the Magnetic Random Access Memory (MRAM), based on magnetoresistive elements, which is non-volatile; consume low power and have fast read and write operations. To make the technology scalable, the bit (the smallest element in the MRAM) needs to
Selective TDP-43 overexpression in oxytocin neurons in the paraventricular nucleus of the hypothalamus causes a decrease in oxytocin-immunopositive cells compared to uninjected mice. AAV-mediated TDP-43 overexpression in oxytocin neurons does not appear to be a major driver of behavioural and metabolic phenotypes in mice.
The centenarian Tröger’s base (TB) was envisaged as scaffold for the construction of tubular-shaped cleft molecules due to its the remarkable structural properties. This endeavor started with the synthesis of the three possible diastereomers of a linear symmetrically fused tris-TB analogue, the anti-anti, the syn-syn, and the syn-anti. All three diastereomers showed unprecedented stability to acid
Given many recent advanced embedding models, selecting pre-trained word representation (ie, word embedding) models best fit for a specific downstream NLP task is non-trivial. In this paper, we propose a systematic approach to extracting, evaluating, and visualizing multiple sets of pre-trained word embed-dings to determine which embeddings should be used in a downstream task. First, for extraction
Out-of-pocket (OOP) expenditures for childbirth in Bangladesh have increased substantially, intensifying financial pressure on lower-income households. While wealthier groups historically bore higher delivery costs, recent trends indicate a narrowing gap in spending across socioeconomic strata. This study investigates the drivers of this convergence in delivery-related expenditures between 2014 an
The Colombian Peace Agreement signed in 2016 was saluted internationally by scholars, policy makers and practitioners for encompassing the concept of territorial peace as a means of ensuring local participation in the strengthening of state institutions. Based on engaged research conducted in the Department of Cauca and Bogotá between 2017 and 2020, we critically analyse territorial peace, explori
Intense agricultural activity in recent years has resulted in a greater use of pesticides in order to improve productivity. However, these pesticides may contain some pollutant component in their composition. Once present in the environment and/or in excess, they can cause damage to the local flora and fauna. The aim of this study was to evaluate the interference of pesticides in the reproductive
In the fourth century B.C., Athenians were often accused of avoiding their civic obligations and of concealing their wealth.1 These attested cases show that economic behaviour in classical Athens could be affected by taxation. The purpose of the present study is to systematically explore the economic incentives resulting from the taxation of wealth. The first issue is the effects of the property t
Deubiquitinating enzymes (DUBs) are specialized proteins that can recognize ubiquitinated proteins, and after direct interaction, deconjugate monomeric or polymeric ubiquitin chains, thus changing the fate of the substrates. This process is instrumental in mediating or changing downstream signaling pathways. Beside mutations and alterations in their expression levels, the activity and stability of
We present recent advances in the modelling and simulation of Internal Traverse Grinding, a high performance grinding process incorporating a high rate of material removal combined with a high surface quality. Due to a special grinding wheel geometry, the latter two goals are achieved in just one pass of the tool through the axisymmetric workpiece. The simulation framework we present generally con
Polyamines are essential polycations involved in a large variety of biological functions, including modulation of the nucleic acid conformation, RNA export and their degradation, protein synthesis, eIF-5A posttranslational modification, signal transduction, cell growth and differentiation, and tumor progression ( 1 –bi3. These various aspects in the biology of polyamines are addressed in other sec
