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Translating Climate Change Adaptation to Local Context and Practice:The case of floods and landslides in Rwanda

The purpose of conducting this study was to analyze how forced expropriations and the demolitions of informal settlements could fall under the umbrella of “climate change adaptation” measures. Using an actor-network lens and translation theory, these translations are systematically broken down between three distinct levels: global discourse, national discourse, and implementation. As the idea of a

"Motherhood Means Business: a motivational factor behind entrepreneurship?” A qualitative study of what can motivate a mother to become an entrepreneur

Title: Motherhood Means Business: a motivational factor in entrepreneurship Seminar date: 1 June 2023 Course: FEKH99, Bachelor Degree Project in Entrepreneurship and Innovation Management, Business administration, 15 University Credit Points Authors: Molly Eklund, Isa Stinger & Stina Svensson Advisor: Ziad El-Awad Keywords: Mother entrepreneurship; motivational factors; Push and Pull theory; O

Influence of constructed wetlands on cyanobacterial growth with regards to the effect of nutrient concentrations and water colour

Can constructed wetlands be used to fight cyanobacterial blooms? Cyanobacterial blooms are more than just a nuisance that prevents swimmers from making the most of the warmest months. Cyanobacterial blooms can cause a wide array of problems such as polluting freshwater reservoirs and causing fish die offs, owing to their ability to grow rapidly and release toxins which are harmful to both humans

Early appearance of thyroid autoimmunity in children followed from birth for type 1 diabetes risk

PURPOSE: Autoantibodies to thyroid peroxidase (TPOAb) and thyroglobulin (TgAb) define pre-clinical autoimmune thyroid disease (AITD) which can progress to either clinical hypo- or hyperthyroidism. We determined the age at seroconversion in children genetically at risk for type 1 diabetes.METHODS: TPOAb and TgAb seropositivity were determined in 5066 healthy children with HLA DR3 or DR4 containing

Oleogels as controlled delivery systems for probiotics

A new encapsulation strategy for probiotics is highly needed to tackle the challenge of significant viability loss of bacteria during storage and passage through the gastrointestinal system. A new controlled delivery system for probiotics based on EC oleogels is proposed in this thesis. A relatively non-complicated in vitro lipolysis model was established to evaluate the relative conversion from t

Taxation in the context of high informality : Conceptual challenges and evidence from Sub-Saharan Africa

The terms ‘informal sector’ and ‘shadow economy’ are in vogue but remain conceptually fuzzy in what they measure or mean. They are used in tax research and policy but with many assumptions, leading to poorly designed policies that lead to further immiseration of those who derive their livelihoods informally. Focusing on Sub-Saharan Africa, I critically interrogate the current conceptualisation of

Unique features of β-cell metabolism are lost in type 2 diabetes

Pancreatic β cells play an essential role in the control of systemic glucose homeostasis as they sense blood glucose levels and respond by secreting insulin. Upon stimulating glucose uptake in insulin-sensitive tissues post-prandially, this anabolic hormone restores blood glucose levels to pre-prandial levels. Maintaining physiological glucose levels thus relies on proper β-cell function. To fulfi

Addressing the challenges of lignin oligomer analysis by liquid-based separation techniques : From universal quantification to multidimensional separations

Lignin is the second most abundant biopolymer on Earth after cellulose, found in virtually all plantswhere it is responsible for rigidity, hydrophobicity and mineral transport. For a long time, it has been considereda waste in the paper production process and incinerated for its energy content. However, with the depletion ofcrude oil reserves, it has been found to have a large potential to become

Urbanisation-associated shifts in the avian metabolome within the annual cycle

While organisms have evolved to cope with predictable changes in the environment, the rapid rate of current global change presents numerous novel and unpredictable stressors to which organisms have had less time to adapt. To persist in the urban environment, organisms must modify their physiology, morphology and behaviour accordingly. Metabolomics offers great potential for characterising organism

Mediators, Metabolites and Atypical Immune Cells in Cardiovascular Disease

Cardiovascular disease (CVD) remains, despite intense research, the most common cause of death world-wide. The main underlying cause of CVD is atherosclerosis, which is characterised by chronic inflammation. CVD and atherosclerosis have a complex aetiology, which necessitates research into multiple areas in order to gain insight into the pathogenesis and find novel markers that could aid in identi

Anti-oxidant effect of nitrite in the pancreatic islets of type 2 diabetic male rats

Objective(s): Nitrite, a nitric oxide (NO) donor, increases insulin secretion from pancreatic islets and has positive metabolic effects in type 2 diabetes (T2D). Here, we test the hypothesis of whether nitrite-induced insulin secretion is due to blunting of diabetes-induced oxidative stress in the islets. Materials and Methods: T2D was created in male rats using a combination of streptozotocin at

Factors assessed in the first year of a longitudinal study predict subsequent study visit compliance : the TEDDY study

Background: Compliance with a study protocol is central to meeting its research goals. In longitudinal research studies, data loss due to missed visits limit statistical power and introduce bias. The Environmental Determinants of Diabetes in the Young (TEDDY) study is a longitudinal multinational (US, Finland, Germany, and Sweden) investigation of children at risk for type 1 diabetes (T1D) that se

Genetic predictors of lifelong medication-use patterns in cardiometabolic diseases

Little is known about the genetic determinants of medication use in preventing cardiometabolic diseases. Using the Finnish nationwide drug purchase registry with follow-up since 1995, we performed genome-wide association analyses of longitudinal patterns of medication use in hyperlipidemia, hypertension and type 2 diabetes in up to 193,933 individuals (55% women) in the FinnGen study. In meta-anal

Metabolite Alterations and Cardiometabolic Disease: A Nutritional Perspective

Background Cardiovascular disease (CVD), type 2 diabetes (T2DM), and atrial fibrillation (AF) collectively impact millions globally, necessitating a comprehensive understanding of preceding metabolic alterations for early intervention. This thesis aims to explore metabolic shifts across populations-based cohorts and evaluate the metabolic impact of a dietary intervention. Method Utilizing liqui